Patents by Inventor Tomonori Akai
Tomonori Akai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10557111Abstract: The object of the present invention is to provide a cell culture vessel having a plurality of microwells, which allows to identify the position of a microwell by observing it under a microscope without moving a viewing position, which has identifiers to be easily disposed to the microwells. The present invention is directed to a cell culture vessel comprising a bottom and a sidewall, in which the bottom has a cell containing section in which a plurality of microwells for containing cells are disposed, identifiers are disposed in the vicinities of the plurality of microwells so as to make pairs in individual microwells, and the relative position of each of the identifiers to a partner microwell varies in every pair.Type: GrantFiled: August 21, 2014Date of Patent: February 11, 2020Assignee: DAI NIPPON PRINTING CO., LTD.Inventors: Tomonori Akai, Masanori Kagota, Takuma Baba
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Patent number: 9805468Abstract: Provided is a sample image management system that uses a cell culture vessel including a plurality of microwells and a plurality of first identifiers provided to the respective microwells in pairs. The sample image management system analyzes, in an enlarged sample image including a pair of the first identifier and the microwell, the microwell and the first identifier, and associates at least position information on the microwell with the enlarged sample image.Type: GrantFiled: August 21, 2014Date of Patent: October 31, 2017Assignee: DAI NIPPON PRINTING CO., LTD.Inventors: Tomonori Akai, Masanori Kagota, Takuma Baba
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Patent number: 9710909Abstract: An object of the present invention is to provide a method for efficiently obtaining mammalian embryos having high conception rates. A first aspect of the present invention is a method for selecting a mammalian embryo prepared by in vitro culture from a fertilized egg, comprising a step of selecting an embryo using two or more of the following indicators: the time from fertilization to the completion of first cleavage; the morphology at a stage after first cleavage and before second cleavage; the morphology at a stage after third cleavage and before fourth cleavage; and the amount of oxygen consumed at the early blastocyst stage, the blastocyst stage, or the expanded blastocyst stage.Type: GrantFiled: September 10, 2015Date of Patent: July 18, 2017Assignee: Dai Nippon Printing Co., Ltd.Inventors: Tomonori Akai, Kei Imai, Yoshio Aikawa, Masaki Ohtake, Satoshi Sugimura
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Publication number: 20160348049Abstract: An object is to provide a cell culture vessel capable of improving culture operability. The present invention relates to a cell culture vessel comprising a bottom and a side wall, wherein at least one microwell for containing a cell is disposed on the bottom, the microwell has a bottom surface, a side surface, and an opening, a convex-concave structure is formed on the side surface of the microwell, and the side surface of the microwell is subjected to hydrophilization treatment.Type: ApplicationFiled: September 10, 2014Publication date: December 1, 2016Inventors: Takuma BABA, Masanori KAGOTA, Tomonori AKAI, Koichiro OKUMURA, Atsumi KIMURA
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Publication number: 20160247280Abstract: An object of the present invention is to provide a means for efficiently obtaining mammalian embryos having high conception rates. A first aspect of the present invention is a method for selecting a mammalian embryo prepared by in vitro culture from a fertilized egg, comprising a step of selecting an embryo using two or more of the following indicators: the time from fertilization to the completion of first cleavage; the morphology at a stage after first cleavage and before second cleavage; the morphology at a stage after third cleavage and before fourth cleavage; and the amount of oxygen consumed at the early blastocyst stage, the blastocyst stage, or the expanded blastocyst stage.Type: ApplicationFiled: September 10, 2015Publication date: August 25, 2016Applicant: Dai Nippon Printing Co., Ltd.Inventors: Tomonori Akai, Kei Imai, Yoshio Aikawa, Masaki Ohtake, Satoshi Sugimura
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Publication number: 20160239957Abstract: Provided is a sample image management system that uses a cell culture vessel including a plurality of microwells and a plurality of first identifiers provided to the respective microwells in pairs.Type: ApplicationFiled: August 21, 2014Publication date: August 18, 2016Inventors: Tomonori AKAI, Masanori KAGOTA, Takuma BABA
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Publication number: 20160222335Abstract: The object of the present invention is to provide a cell culture vessel having a plurality of microwells, which allows to identify the position of a microwell by observing it under a microscope without moving a viewing position, which has identifiers to be easily disposed to the microwells. The present invention is directed to a cell culture vessel comprising a bottom and a sidewall, in which the bottom has a cell containing section in which a plurality of microwells for containing cells are disposed, identifiers are disposed in the vicinities of the plurality of microwells so as to make pairs in individual microwells, and the relative position of each of the identifiers to a partner microwell varies in every pair.Type: ApplicationFiled: August 21, 2014Publication date: August 4, 2016Applicant: Dai Nippon Printing Co., Ltd.Inventors: Tomonori AKAI, Masanori KAGOTA, Takuma BABA
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Patent number: 9163274Abstract: An object of the present invention is to provide a means for efficiently obtaining mammalian embryos having high conception rates. A first aspect of the present invention is a method for selecting a mammalian embryo prepared by in vitro culture from a fertilized egg, comprising a step of selecting an embryo using two or more of the following indicators: the time from fertilization to the completion of first cleavage; the morphology at a stage after first cleavage and before second cleavage; the morphology at a stage after third cleavage and before fourth cleavage; and the amount of oxygen consumed at the early blastocyst stage, the blastocyst stage, or the expanded blastocyst stage.Type: GrantFiled: June 30, 2011Date of Patent: October 20, 2015Assignee: Dai Nippon Printing Co., Ltd.Inventors: Tomonori Akai, Kei Imai, Yoshio Aikawa, Masaki Ohtake, Satoshi Sugimura
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Patent number: 9155159Abstract: A QD protecting material having high compatibility with a binder component in a luminescent layer. The luminescent layer contains, as a part of its chemical structure, a compound containing a moiety A having a sum atomic weight MA of 100 or more and quantum dots protected by a protecting material, the protecting material contains, as a part of its chemical structure, a linking group connected to a quantum dot surface and a moiety B that has a sum atomic weight MB of 100 or more, satisfies a relationship between MB and MA represented by |MA?MB|/MB (2, and satisfies the requirement that the sum atomic weight MB is larger than one-third of the molecular weight of the protecting material, and a solubility parameter SA of the moiety A and a solubility parameter SB of the moiety B satisfy a relationship represented by |SA (SB| (2.Type: GrantFiled: September 29, 2008Date of Patent: October 6, 2015Assignee: Dai Nippon Printing Co., Ltd.Inventors: Masato Okada, Shigehiro Ueno, Tomonori Akai, Masaya Shimogawara, Seiji Take
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Patent number: 9062341Abstract: This invention provides a means for cell migration assays by regulating the cells adhered to a substrate so that they migrate to a given region, which is a substrate used for cell culture comprising: a base material comprising a conductive region and an insulating region provided thereon and cell-adhesive regions and non-cell-adhesive regions provided in the conductive region and the insulating region, respectively, wherein a cell-adhesive region is positioned adjacent to a non-cell-adhesive region in the conductive region, and a cell-adhesive region is positioned adjacent to a non-cell-adhesive region in the insulating region.Type: GrantFiled: December 6, 2010Date of Patent: June 23, 2015Assignee: DAI NIPPON PRINTING CO., LTD.Inventors: Naoki Yokoyama, Tomonori Akai, Yuya Takasugi
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Patent number: 8860097Abstract: Provided is a biosensor that makes it possible to detect the electrical properties of a bio-related material contained in an analyte fluid such as an aqueous solution placed on a sensitive membrane and to observe the bio-related material at a high magnification with an observation device such as a microscope.Type: GrantFiled: June 14, 2011Date of Patent: October 14, 2014Assignee: Dai Nippon Printing Co., Ltd.Inventors: Takuya Higuchi, Tomonori Akai, Katsuyuki Motai
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Patent number: 8759100Abstract: This invention provides a means for modifying surface properties of a cell culture substrate under specific conditions, to thereby regulate regions to which cells are allowed to adhere or are not allowed to adhere, depending on cell type. This invention relates to a method of cell culture comprising steps of: applying a positive potential to a conductive region of a substrate comprising a base material having a conductive region and a non-cell-adhesive membrane coupled thereto with the aid of silane, so as to separate the non-cell-adhesive membrane from the substrate; and culturing cells in a region from which the non-cell-adhesive membrane has been separated.Type: GrantFiled: December 6, 2010Date of Patent: June 24, 2014Assignee: Dai Nippon Printing Co., Ltd.Inventors: Naoki Yokoyama, Tomonori Akai
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Patent number: 8685328Abstract: In order to remove a pathogenic effect of a microorganism in a room or a work space in a short period of time, an ion diffusing apparatus, which includes an ion generator (17, 18) for generating positive ions each including H+(H2O)m and negative ions each including O2?(H2O)n, where m and n are arbitrary integers, and a blower for delivering the positive ions and the negative ions, which are generated from the ion generator (17), from a blowout opening, is operated to widely distribute, with a high concentration, the positive ions and the negative ions in the room.Type: GrantFiled: May 21, 2009Date of Patent: April 1, 2014Assignee: Sharp Kabushiki KaishaInventors: Hiroaki Okano, Kazuo Nishikawa, Hisaharu Yagi, Norihiro Matsuoka, Tomonori Akai, Misaki Nakamura, Yoshihiro Shimizu
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Patent number: 8563968Abstract: The present invention provides an EL device that contains a quantum-dots-containing layer in which quantum dots hardly coagulate even under high-temperature conditions, e.g., at a temperature of 90° C. or more, that has a good performance even if heat treatment was carried at a high temperature in its production process, that can retain its emission characteristics for a prolonged period of time, and that has high durability. An electroluminescent device comprises a pair of electrodes, and an electroluminescent layer containing at least a luminescent layer, situated between the electrodes. The luminescent layer contains quantum dots whose surfaces are protected by one or more protective materials. At least one of the protective materials has a glass transition temperature and a melting point of 90° C. or more.Type: GrantFiled: September 26, 2008Date of Patent: October 22, 2013Assignee: Dai Nippon Printing Co., Ltd.Inventors: Tomonori Akai, Yasuhiro Iizumi
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Publication number: 20130244328Abstract: This invention provides a means for modifying surface properties of a cell culture substrate under specific conditions, to thereby regulate regions to which cells are allowed to adhere or are not allowed to adhere, depending on cell type. This invention relates to a method of cell culture comprising steps of: applying a positive potential to a conductive region of a substrate comprising a base material having a conductive region and a non-cell-adhesive membrane coupled thereto with the aid of silane, so as to separate the non-cell-adhesive membrane from the substrate; and culturing cells in a region from which the non-cell-adhesive membrane has been separated.Type: ApplicationFiled: December 6, 2010Publication date: September 19, 2013Applicant: DAI NIPPON PRINTING CO., LTD.Inventors: Naoki Yokoyama, Tomonori Akai
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Publication number: 20130210068Abstract: This invention provides a means for cell migration assays by regulating the cells adhered to a substrate so that they migrate to a given region, which is a substrate used for cell culture comprising: a base material comprising a conductive region and an insulating region provided thereon and cell-adhesive regions and non-cell-adhesive regions provided in the conductive region and the insulating region, respectively, wherein a cell-adhesive region is positioned adjacent to a non-cell-adhesive region in the conductive region, and a cell-adhesive region is positioned adjacent to a non-cell-adhesive region in the insulating region.Type: ApplicationFiled: December 6, 2010Publication date: August 15, 2013Applicant: DAI NIPPON PRINTING CO., LTD.Inventors: Naoki Yokoyama, Tomonori Akai, Yuya Takasugi
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Publication number: 20130116499Abstract: An object of the present invention is to provide a means for efficiently obtaining mammalian embryos having high conception rates. A first aspect of the present invention is a method for selecting a mammalian embryo prepared by in vitro culture from a fertilized egg, comprising a step of selecting an embryo using two or more of the following indicators: the time from fertilization to the completion of first cleavage; the morphology at a stage after first cleavage and before second cleavage; the morphology at a stage after third cleavage and before fourth cleavage; and the amount of oxygen consumed at the early blastocyst stage, the blastocyst stage, or the expanded blastocyst stage.Type: ApplicationFiled: June 30, 2011Publication date: May 9, 2013Applicant: Dai Nippon Printing Co., Ltd.Inventors: Tomonori Akai, Kei Imai, Yoshio Aikawa, Masaki Ohtake, Satoshi Sugimura
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Publication number: 20130075793Abstract: Provided is a biosensor that makes it possible to detect the electrical properties of a bio-related material contained in an analyte fluid such as an aqueous solution placed on a sensitive membrane and to observe the bio-related material at a high magnification with an observation device such as a microscope.Type: ApplicationFiled: June 14, 2011Publication date: March 28, 2013Applicant: DAI NIPPON PRINTING CO., LTD.Inventors: Takuya Higuchi, Tomonori Akai, Katsuyuki Motai
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Patent number: 8384064Abstract: An electroluminescent device comprising a pair of electrodes, and an electroluminescent layer containing at least a luminescent layer, situated between the electrodes. The luminescent layer has a matrix material containing at least one organic compound, and quantum dots whose surfaces are protected by a protective material and that are dispersed in the matrix material. The protective material contains a first protective material. The absolute value of the ionization potential Ip(h), the absolute value of the electron affinity Ea(h), and the band gap Eg(h) of the first protective material, the absolute value of the ionization potential Ip(m), the absolute value of the electron affinity Ea(m), and the band gap Eg(m) of the organic compound, and the band gap Eg(q) of the quantum dots fulfill all of the conditions (A) to (C): (A) Ip(h)<Ip(m)+0.1 eV, (B) Ea(h)>Ea(m)?0.1 eV, and (C) Eg(q)<Eg(h)<Eg(m).Type: GrantFiled: September 26, 2008Date of Patent: February 26, 2013Assignee: Dai Nippon Printing Co., Ltd.Inventors: Tomonori Akai, Yasuhiro Iizumi
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Patent number: 7939999Abstract: The present invention provides an electroluminescence device which can overcome a drawback that a light emitting layer deteriorates when a cathode layer is formed on the light emitting layer and has no decline in the original function; and a production method which is suitable for producing such an electroluminescence device. An electroluminescence device has a laminated structure wherein an anode layer, a light emitting layer, a charge transporting protection layer, and a cathode layer are successively formed on a substrate, in which the charge transporting protection layer comprises a transparent insulating material, or a transparent insulating material and a metal.Type: GrantFiled: August 24, 2006Date of Patent: May 10, 2011Assignee: Dai Nippon Printing Co., Ltd.Inventors: Tomonori Akai, Shigehiro Ueno