Patents by Inventor Tomoya Akutagawa
Tomoya Akutagawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10300021Abstract: The present invention provides an intraorally rapidly disintegrating tablet that can be formed using an ordinary apparatus, that has hardness with no practical problem and that disintegrates rapidly with good feeling in the oral cavity. The present invention is intraorally rapidly disintegrating tablet produced by compression molding of a granule coated with a disintegrant, in which the granule contains a disintegrant also inside thereof and a drug except ambroxol hydrochloride inside and/or outside thereof.Type: GrantFiled: November 14, 2006Date of Patent: May 28, 2019Assignee: Teijin Pharma LimitedInventors: Tomoya Akutagawa, Masahiko Narasaki
-
Patent number: 9511029Abstract: The present invention provides an intraorally rapidly disintegrating tablet that can be formed using an ordinary apparatus, that has hardness with no practical problem and that disintegrates rapidly with good feeling in the oral cavity. The present invention is intraorally rapidly disintegrating tablet produced by compression molding of a granule coated with a disintegrant, in which the granule contains a disintegrant also inside thereof and a drug except ambroxol hydrochloride inside and/or outside thereof.Type: GrantFiled: September 18, 2009Date of Patent: December 6, 2016Assignee: Teijin Pharma LimitedInventors: Tomoya Akutagawa, Masahiko Narasaki
-
Patent number: 9078807Abstract: A tablet compression machine which can manufacture a tablet having a plurality of layers by applying secondary compression molding to a columnar primary compression molded product formed by a plurality of layers and whose two bottom faces may be bulged, comprising at least a mortar, an upper pestle, and a lower pestle, in which the mortar is substantially in a shape in which a part of a flat plate is punched by a closed curve in a direction perpendicular to a plane of the flat plate, the upper and lower pestles are in a shape fitted with an inner face of the mortar, a space formed by an inner face of the mortar, a lower face of the upper pestle, and an upper face of the lower pestle is in a shape of an intended tablet in the secondary compression molding, a dent formed by the inner face of the mortar and the upper face of the lower pestle can constitute a shape suitable for receiving the primary compression molded product, and a direction of the secondary compression molding is different from the compressionType: GrantFiled: February 15, 2008Date of Patent: July 14, 2015Assignee: Teijin Pharma LimitedInventors: Masahiko Narasaki, Tomoya Akutagawa, Takamasa Maki, Minoru Uemura
-
Patent number: 9028867Abstract: The present invention provides a tablet comprising a plurality of drug-containing parts and at least one connecting part adhered to the drug-containing parts, and having a scored line capable of dividing the whole tablet on the connecting part; particularly, a coated tablet in which a connecting part and a coating layer have the same or different drug release controlling functions; a tablet having an insoluble coating on a drug-containing part having a scored line, wherein the drug-containing part has a structure or composition such that the drug is substantially released after the tablet is divided along the scored line and then ingested; and a tablet comprising a plurality of drug-containing parts and at least one connecting part adhered to the drug-containing parts, wherein at least two drug-containing parts have different compositions.Type: GrantFiled: August 17, 2006Date of Patent: May 12, 2015Assignee: Teijin Pharma LimitedInventors: Masahiko Narasaki, Tomoya Akutagawa, Reiko Oku
-
Publication number: 20130101670Abstract: [OBJECT] To provide an intraorally rapidly disintegrating tablet comprising 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid as an active ingredient, which is a formulation that causes virtually no irritating sensation in the oral cavity or pharynx, and retains good dissolution and oral disintegration properties even when it is stored under high temperature/high humidity conditions. [MEANS OF REALIZING THE OBJECT] An intraorally rapidly disintegrating tablet comprising a particle containing a 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid-containing core particle coated with a layer comprising a methacrylic acid copolymer and further overcoated with a layer containing a water-soluble saccharide.Type: ApplicationFiled: July 8, 2011Publication date: April 25, 2013Applicant: TEIJIN PHARMA LIMITEDInventors: Kazuhiro Nakamura, Teppei Ogawa, Tomoya Akutagawa
-
Patent number: 8029261Abstract: A transfer board for transferring a columnar primary compression molded product which is supplied continuously one by one vertically in a shooter into a mortar of a secondary tablet compression machine, having at least an inclined portion having a plane-state inclined face, an input portion adjacent thereto, a portion for limiting drop of primary compression molded product, and a bottom plate provided at a lower part of the input portion, the inclined face being inclined so as to become lower toward the input portion, the inclined portion and the adjacent input portion performing a linear motion or rotary motion at a constant speed horizontally in a direction opposite to the input portion, and the input portion and the bottom plate being able to supply the primary compression molded product into the mortar of the secondary tablet compression machine while the columnar direction is kept substantially in a state of the horizontal direction.Type: GrantFiled: February 19, 2008Date of Patent: October 4, 2011Assignee: Teijin Pharma LimitedInventors: Masahiko Narasaki, Tomoya Akutagawa, Takamasa Maki, Minoru Uemura
-
Publication number: 20100092596Abstract: A tablet compression machine which can manufacture a tablet having a plurality of layers by applying secondary compression molding to a columnar primary compression molded product formed by a plurality of layers and whose two bottom faces may be bulged, comprising at least a mortar, an upper pestle, and a lower pestle, in which the mortar is substantially in a shape in which a part of a flat plate is punched by a closed curve in a direction perpendicular to a plane of the flat plate, the upper and lower pestles are in a shape fitted with an inner face of the mortar, a space formed by an inner face of the mortar, a lower face of the upper pestle, and an upper face of the lower pestle is in a shape of an intended tablet in the secondary compression molding, a dent formed by the inner face of the mortar and the upper face of the lower pestle can constitute a shape suitable for receiving the primary compression molded product, and a direction of the secondary compression molding is different from the compressionType: ApplicationFiled: February 15, 2008Publication date: April 15, 2010Applicant: TEIJIN PHARMA LIMITEDInventors: Masahiko Narasaki, Tomoya Akutagawa, Takamasa Maki, Minoru Uemura
-
Publication number: 20100092592Abstract: A transfer board for transferring a columnar primary compression molded product whose two bottom faces may be bulged and which is supplied continuously one by one due to its own weight since the products continue vertically in a shooter into a mortar of a secondary tablet compression machine, for example, rotary tablet compression machine, in a state where the columnar direction is substantially horizontal, having at least an inclined portion having a plane-state inclined face, an input portion adjacent thereto, a portion for limiting drop of primary compression molded product, and a bottom plate provided at a lower part of the input portion, the inclined face being inclined so as to become lower toward the input portion, the inclined portion and the adjacent input portion performing a linear motion or rotary motion at a constant speed horizontally in a direction opposite to the input portion, and the input portion and the bottom plate being able to supply the primary compression molded product into the mortaType: ApplicationFiled: February 19, 2008Publication date: April 15, 2010Applicant: TEIJIN PHARMA LIMITRDInventors: Masahiko Narasaki, Tomoya Akutagawa, Takamasa Maki, Minoru Uemura
-
Publication number: 20100009004Abstract: The present invention provides an intraorally rapidly disintegrating tablet that can be formed using an ordinary apparatus, that has hardness with no practical problem and that disintegrates rapidly with good feeling in the oral cavity. The present invention is intraorally rapidly disintegrating tablet produced by compression molding of a granule coated with a disintegrant, in which the granule contains a disintegrant also inside thereof and a drug except ambroxol hydrochloride inside and/or outside thereof.Type: ApplicationFiled: September 18, 2009Publication date: January 14, 2010Applicant: TEIJIN PHARMA LIMITEDInventors: Tomoya AKUTAGAWA, Masahiko Narasaki
-
Publication number: 20090155361Abstract: A tablet which is either a two-layer tablet comprising a layer A and a layer B or a three-layer tablet comprising a layer A, a layer B and a layer C in that order, wherein the layer B is a medicinal additive layer, the layer A and the layer C are drug layers that are segmented on the layer B, and the sections of the layer A and the layer C are held on the layer B and contain either the same or different drugs. Also, a scored tablet wherein splitting at one of the score lines produces two fragments with equal drug contents and splitting at the other score line produces two fragments with unequal drug contents. In addition, a scored tablet wherein splitting at the score lines exposes cross-sections with different drug release-controlling functions.Type: ApplicationFiled: August 18, 2006Publication date: June 18, 2009Inventors: Masahiko Narasaki, Tomoya Akutagawa, Reiko Oku
-
Publication number: 20090117182Abstract: The present invention provides an intraorally rapidly disintegrating tablet that can be formed using an ordinary apparatus, that has hardness with no practical problem and that disintegrates rapidly with good feeling in the oral cavity. The present invention is intraorally rapidly disintegrating tablet produced by compression molding of a granule coated with a disintegrant, in which the granule contains a disintegrant also inside thereof and a drug except ambroxol hydrochloride inside and/or outside thereof.Type: ApplicationFiled: November 14, 2006Publication date: May 7, 2009Applicant: Teijin Pharma LimitedInventors: Tomoya Akutagawa, Masahiko Narasaki
-
Publication number: 20090110726Abstract: The present invention provides a tablet comprising a plurality of drug-containing parts and at least one connecting part adhered to the drug-containing parts, and having a scored line capable of dividing the whole tablet on the connecting part; particularly, a coated tablet in which a connecting part and a coating layer have the same or different drug release controlling functions; a tablet having an insoluble coating on a drug-containing part having a scored line, wherein the drug-containing part has a structure or composition such that the drug is substantially released after the tablet is divided along the scored line and then ingested; and a tablet comprising a plurality of drug-containing parts and at least one connecting part adhered to the drug-containing parts, wherein at least two drug-containing parts have different compositions.Type: ApplicationFiled: August 17, 2006Publication date: April 30, 2009Applicant: TEIJIN PHARMA LIMITEDInventors: Masahiko Narasaki, Tomoya Akutagawa, Reiko Oku