Patents by Inventor Tomoya Kotake

Tomoya Kotake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS
    Publication number: 20250051394
    Abstract: Cyclic compounds that selectively inhibit KRAS were found. Moreover, cyclic compounds were found to interact with an amino acid residue specific to KRAS.
    Type: Application
    Filed: September 10, 2024
    Publication date: February 13, 2025
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Hatsuo KAWADA, Koji TAKANO, Tomoya KOTAKE, Mirai KAGE, Satoshi HASHIMOTO, Minoru TAMIYA, Yuma WAKAMIYA, Ryuji HAYASHI, Yuya MORITA
  • CYCLIC COMPOUND HAVING SELECTIVE INHIBITORY ACTION ON KRAS OVER HRAS AND NRAS
    Publication number: 20240158446
    Abstract: Cyclic compounds and oligopeptide compounds that selectively inhibit KRAS were found. Oligopeptide compounds and non-natural amino acids useful for producing a cyclic compound were also found. Moreover, cyclic compounds and oligopeptide compounds were found to interact with an amino acid residue specific to KRAS.
    Type: Application
    Filed: May 6, 2022
    Publication date: May 16, 2024
    Inventors: Hatsuo KAWADA, Koji TAKANO, Tomoya KOTAKE, Mirai KAGE, Satoshi HASHIMOTO, Minoru TAMIYA, Yuma WAKAMIYA, Ryuji HAYASHI, Yuya MORITA
  • Reactor
    Patent number: 10738137
    Abstract: A polymerization device that includes: a reaction vessel that houses a polymerization solution and in which a polymerization reaction is performed; a stirring blade that stirs the polymerization solution housed in the reaction vessel; a plurality of heat transfer pipes that transfer heat to the polymerization solution in order to start the polymerization reaction and cause the polymerization reaction to proceed, and that remove, from the polymerization solution, heat generated by the polymerization reaction; and a baffle arranged between a vessel wall of the reaction vessel and the heat transfer pipes.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: August 11, 2020
    Assignee: KUREHA CORPORATION
    Inventors: Tomoya Kotake, Noriyuki Yoshio, Shuhei Nishiyama, Misato Matsuoka
  • REACTOR
    Publication number: 20200040111
    Abstract: A polymerization device that includes: a reaction vessel that houses a polymerization solution and in which a polymerization reaction is performed; a stirring blade that stirs the polymerization solution housed in the reaction vessel; a plurality of heat transfer pipes that transfer heat to the polymerization solution in order to start the polymerization reaction and cause the polymerization reaction to proceed, and that remove, from the polymerization solution, heat generated by the polymerization reaction; and a baffle arranged between a vessel wall of the reaction vessel and the heat transfer pipes.
    Type: Application
    Filed: October 15, 2019
    Publication date: February 6, 2020
    Inventors: Tomoya KOTAKE, Noriyuki YOSHIO, Shuhei NISHIYAMA, Misato MATSUOKA
  • REACTOR
    Publication number: 20200024371
    Abstract: A polymerization device that includes: a reaction vessel that houses a polymerization solution and in which a polymerization reaction is performed; a stirring blade that stirs the polymerization solution housed in the reaction vessel; a plurality of heat transfer pipes that transfer heat to the polymerization solution in order to start the polymerization reaction and cause the polymerization reaction to proceed, and that remove, from the polymerization solution, heat generated by the polymerization reaction; and a baffle arranged between a vessel wall of the reaction vessel and the heat transfer pipes.
    Type: Application
    Filed: April 24, 2019
    Publication date: January 23, 2020
    Inventors: Tomoya KOTAKE, Noriyuki YOSHIO, Shuhei NISHIYAMA, Misato MATSUOKA
  • Spiroimidazolone derivative
    Patent number: 9487517
    Abstract: The present invention relates to a compound represented by the following formula (1): wherein W, X, Y, R1, R2, R33, R34, m and n are as defined in the claims, or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: November 8, 2016
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Toru Esaki, Yoshikazu Nishimura, Yoshiaki Isshiki, Naoki Okamoto, Yoshiyuki Furuta, Akemi Mizutani, Masateru Ohta, Wayne Wen Lai, Tomoya Kotake
  • SPIROIMIDAZOLONE DERIVATIVE
    Publication number: 20160016956
    Abstract: The present invention relates to a compound represented by the following formula (1): wherein W, X, Y, R1, R2, R33, R34, m and n are as defined in the claims, or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: September 17, 2015
    Publication date: January 21, 2016
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Toru Esaki, Yoshikazu NISHIMURA, Yoshiaki ISSHIKI, Naoki OKAMOTO, Yoshiyuki FURUTA, Akemi MIZUTANI, Masateru OHTA, Wayne Wen LAI, Tomoya KOTAKE
  • Spiroimidazolone derivative
    Patent number: 9169254
    Abstract: The present invention relates to a compound represented by the following formula (1): wherein W, X, Y, R1, R2, R33, R34, m and n are as defined in the claims, or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: October 27, 2015
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Toru Esaki, Yoshikazu Nishimura, Yoshiaki Isshiki, Naoki Okamoto, Yoshiyuki Furuta, Akemi Mizutani, Masateru Ohta, Wayne Wen Lai, Tomoya Kotake
  • SPIROIMIDAZOLONE DERIVATIVE
    Publication number: 20120270838
    Abstract: The present invention relates to a compound represented by the following formula (1): wherein W, X, Y, R1, R2, R33, R34, m and n are as defined in the claims, or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: April 27, 2010
    Publication date: October 25, 2012
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Toru Esaki, Yoshikazu Nishimura, Yoshiaki Isshiki, Naoki Okamoto, Yoshiyuki Furuta, Akemi Mizutani, Masateru Ohta, Wayne Wen Lai, Tomoya Kotake