Abstract: A liquid crystal compound, a liquid crystal composition, and a liquid crystal electric optical device having a low rotational viscosity (?1) and appropriate elastic constants. A fluorine-containing liquid crystal compound represented by formula (1). R1-(A1-Z1)a-(A2-Z2)b-(A3-Z3)c-A4-(CH2)n-CF?CF—R2 (1), R1 is a hydrogen atom, a halogen atom, or an alkyl group, R2 is a halogen atom or an alkyl group that may be halogen-substituted or which may include a (thio)ether group, A1 to A4 may be a phenylene group or a cyclohexylene group that may be halogen-substituted or which may include a (thio)ether group, Z1 to Z3 are a single bond, —O—, —S—, or a divalent aliphatic hydrocarbon group that may be halogen-substituted or which may include a (thio)ether group. n is an integer from 0 to 3, and a, b, and c are 0 or 1, provided that a+b+c is 1 or greater.

Abstract: Disclosed is a liquid crystal composition suitable for producing a liquid crystal electrooptical element which can be driven at a low voltage in a wide temperature range and has high display quality. Also disclosed is a liquid crystal electrooptical element produced by using the liquid crystal composition. Further disclosed is a liquid crystal compound useful in preparing this composition.

Abstract: Disclosed is a liquid crystal composition suitable for producing a liquid crystal electrooptical element which can be driven at a low voltage in a wide temperature range and has high display quality. Also disclosed is a liquid crystal electrooptical element produced by using the liquid crystal composition. Further disclosed is a liquid crystal compound represented by the formula [R1-(A1)a-Z1-(A2)b-Z2-(A7)e-Z5-A3-CF?CFCF2O-A4-Z3-(A5)c-Z4-(A6)d-R2].

Abstract: Disclosed is a liquid crystal composition suitable for producing a liquid crystal electrooptical element which can be driven at a low voltage in a wide temperature range and has high display quality. Also disclosed is a liquid crystal electrooptical element produced by using the liquid crystal composition. Further disclosed is a liquid crystal compound represented by the formula [R1-(A1)a-Z1-(A2)b-Z2-(A7)e-Z5-A3—CF?CFCF2O-A4-Z3-(A5)c-Z4-(A6)d-R2].

Abstract: Disclosed is a liquid crystal composition suitable for producing a liquid crystal electrooptical element which can be driven at a low voltage in a wide temperature range and has high display quality. Also disclosed is a liquid crystal electrooptical element produced by using the liquid crystal composition. Further disclosed is a liquid crystal compound useful in preparing this composition.

Abstract: A liquid crystal compound, a liquid crystal composition, and a liquid crystal electric optical device having a low rotational viscosity (?1) and appropriate elastic constants. A fluorine-containing liquid crystal compound represented by formula (1). R1-(A1-Z1)a-(A2-Z2)b-(A3-Z3)c-A4-(CH2)n-CF?CF—R2 (1), R1 is a hydrogen atom, a halogen atom, or an alkyl group, R2 is a halogen atom or an alkyl group that may be halogen-substituted or which may include a (thio)ether group, A1 to A4 may be a phenylene group or a cyclohexylene group that may be halogen-substituted or which may include a (thio)ether group, Z1 to Z3 are a single bond, —O—, —S—, or a divalent aliphatic hydrocarbon group that may be halogen-substituted or which may include a (thio)ether group. n is an integer from 0 to 3, and a, b, and c are 0 or 1, provided that a+b+c is 1 or greater.

Abstract: The present invention is concerned with a novel process for the preparation of 1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-one (CAS 30071-93-3). This compound is useful as an intermediate in the synthesis of therapeutic agents.

Abstract: The present invention is concerned with a novel process for the preparation of 1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-one (CAS 30071-93-3). This compound is useful as an intermediate in the synthesis of therapeutic agents.

Abstract: A method for producing an optically active 1-substituted 2-propanol of the following formula 1, which comprises reacting a hydroxy aromatic compound of the following formula 2 with an optically active propylene oxide in the presence of a catalyst: AOH  Formula 2 CH3C*H(OH)CH2OA  Formula 1 wherein A is a univalent aromatic group, and C* is an asymmetric carbon atom.

Abstract: A novel prostaglandin I.sub.2 derivative selected from a prostaglandin I.sub.2 having a halogen atom on the carbon atom corresponding to the 7-position of natural prostaglandin I.sub.2 and having a cycloalkylene group in the .alpha.-chain, and its esters and salts.

Abstract: A 6-fluoroprostaglandin having the formula: ##STR1## wherein A is a carbonyl group or a hydroxymethylene group, R.sup.1 is a substituted or unsubstituted C.sub.1 -C.sub.10 alkyl group or a substituted or unsubstituted 5- or 6-membered cycloalkyl group, R.sup.2 is a hydrogen atom or a C.sub.1 -C.sub.10 alkyl group, each of R.sup.3 and R.sup.4 which may be the same or different is a hydrogen atom or a protecting group, R.sup.5 is a hydrogen atom or a hydroxyl group, and is a single bond or a double bond, and its salt when R.sup.2 is a hydrogen atom.