Abstract: Crystals comprising (2R)-2-propyloctoic acid and an amine which retain the pharmacological effect of (2R)-2-propyloctoic acid and can be safely used as a medicinal raw drug for peroral solid preparations. Of these crystals, the crystals especially with dibenzylamine are advantageous because not only the crystals themselves are useful as a medicinal raw drug but also use of the crystals as an intermediate can yield (2R)-2-propyloctoic acid having an optical purity exceeding 99.5% e.e., which has not been obtained hitherto.

Abstract: The present invention provides a dielectric porcelain composition comprising 100 parts by weight of a barium titanate-based dielectric material and 4 to 10 parts by weight in total of Bi2O3 and at least one compound selected from the group of consisting of CuO, ZnO and MgO.

Abstract: It is provided a ceramic multilayer substrate obtained by co-sintering a low dielectric constant layer made of an insulating material of a low dielectric constant and a high dielectric constant layer of a dielectric material of a high dielectric constant. The low dielectric constant layer includes a ceramic component of xBaO-yTiO2-zZnO (“x”, “y” and “z” represent molar ratios, respectively, and satisfy the relationship: x+y+z=1; 0.09?x?0.20; 0.49?y?0.61; 0.19?z?0.42) and 1.0 to 5.0 weight parts of a glass component comprising boron oxide with respect to 100 weight parts of the ceramic component. The high dielectric layer is made of a barium titanate based dielectric material with CuO and Bi2O3 added thereto.

Abstract: While one video reel is being scrolled and the remaining video reels stop scrolling, a map of Japan or a map of America is displayed on a liquid crystal panel. A territory corresponding to a player is distinguished by color on the map. There is a correlation in terms of probability between the territory corresponding to the player distinguished by color and a payout amount corresponding to a symbol combination to be realized upon stop of scroll of all the video reels.

Abstract: A gaming machine of the present invention performs an effect of rotating an image displayed in each display block having a second specific symbol rearranged therein in a direction so as to turn a display screen of a display over to the other side after scroll-displaying a specific character image to the display in a direction from one side of a symbol display region toward the opposite side, and also changing the second specific symbol rearranged in the each display block into a first specific symbol, when the first specific symbol and the second specific symbol have been rearranged in the symbol display region and also when it has been determined to display the specific character image; and offers an award in accordance with the number of first specific symbols arranged in the symbol display region as a result thereof.

Abstract: The present invention relates to a process for producing (2R)-2-propyloctanoic acid, which comprises subjecting (2R)-2-hexyloxirane to a two-carbon adding reaction with ring-opening reaction, followed by a protecting reaction of a hydroxyl group to convert it to a compound represented by formula (I): (wherein X represents an optionally protected hydroxyl group) and then subjecting the compound to a one-carbon adding reaction to convert it to (2R)-2-propyloctanamide, followed by recrystallization and hydrolysis. According to the process of the present invention, (2R)-2-propyloctanoic acid can be produced by less steps as compared with the conventional method without a dangerous reaction.

Abstract: The present invention relates to a compound represented by formula (I) wherein R1 represents optionally protected hydroxy or oxo, indicates ?-configuration, ?-configuration or a mixture of these in an arbitrary proportion, n represents an integer of 1 to 3, and m represents 0 or an integer of 1 to 10; and wherein two or more R1's are not bound to the same carbon atom other than the terminal carbon atom, a salt thereof or a prodrug thereof. The compounds represented by formula (I) have an ability to improve astrocyte function, and they are useful as a preventive and/or therapeutic agent for a brain infarction, neuronal dysfunction by brain infarction, Parkinson's disease, Parkinson's syndrome, amyotrophic lateral sclerosis or Alzheimer's disease.

Abstract: The present invention provides an IC tag which has a structure comprising a first adhesive layer formed on a surface of a substrate sheet, an electronic circuit and an IC chip connecting both ends of the electronic circuit, both formed on the surface of the first adhesive layer, and a second adhesive layer covering the electronic circuit and the IC chip. The IC tag further includes a release agent layer formed at positions corresponding to the both ends of the electronic circuit and located at the interface between the substrate sheet and the first adhesive layer. When the IC tag attached to an article is peeled off, the built-in electronic circuit is surely broken.

Abstract: The present invention provides a dielectric porcelain composition comprising 100 parts by weight of a barium titanate-based dielectric material and 4 to 10 parts by weight in total of Bi2O3 and at least one compound selected from the group of consisting of CuO, ZnO and MgO.

Abstract: Crystals comprising (2R)-2-propyloctoic acid and an amine which retain the pharmacological effect of (2R)-2-propyloctoic acid and can be safely used as a medicinal raw drug for peroral solid preparations. Of these crystals, the crystals especially with dibenzylamine are advantageous because not only the crystals themselves are useful as a medicinal raw drug but also use of the crystals as an intermediate can yield (2R)-2-propyloctoic acid having an optical purity exceeding 99.5% e.e., which has not been obtained hitherto.

Abstract: The present invention relates to a compound represented by formula (I) wherein R1 represents optionally protected hydroxy or oxo, indicates ?-configuration, ?-configuration or a mixture of these in an arbitary proportion, n represents an integer of 1 to 3, and m represents 0 or an integer of 1 to 10; and wherein two or more R1's are not bound to the same carbon atom other than the terminal carbon atom, a salt thereof or a prodrug thereof. The compounds represented by formula (I) have an ability to improve astrocyte function, and they are useful as a preventive and/or therapeutic agent for a brain infarction, neuronal dysfunction by brain infarction, Parkinson's disease, Parkinson's syndrome, amyotrophic lateral sclerosis or Alzheimer's disease.

Abstract: Indole derivatives represented by formula (I) wherein all symbols represent the same as that in specification), production methods thereof, and DP receptor antagonist comprising them as active ingredients. Since the compounds of formula (I) binds and antagonizes to DP receptor, they are useful for the prevention and/or treatment against allergic diseases, diseases accompanied with itching, secondary diseases generated by behaviors caused by itching, inflammation, chronic obstructive pulmonary disease, ischemic reperfusion disorder, cerebrovascular disorder, pleuritis complicated by rheumatoid arthritis, ulcerative colitis.

Abstract: The present invention provides an IC tag which has a structure comprising a first adhesive layer formed on a surface of a substrate sheet, an electronic circuit and an IC chip connecting both ends of the electronic circuit, both formed on the surface of the first adhesive layer, and a second adhesive layer covering the electronic circuit and the IC chip. The IC tag further includes a release agent layer formed at positions corresponding to the both ends of the electronic circuit and located at the interface between the substrate sheet and the first adhesive layer. When the IC tag attached to an article is peeled off, the built-in electronic circuit is surely broken.

Abstract: The present invention relates to a process for producing (2R)-2-propyloctanoic acid, which comprises subjecting (2R)-2-hexyloxirane to a two-carbon adding reaction with ring-opening reaction, followed by a protecting reaction of a hydroxyl group to convert it to a compound represented by formula (I): (wherein X represents an optionally protected hydroxyl group) and then subjecting the compound to a one-carbon adding reaction to convert it to (2R)-2-propyloctanamide, followed by recrystallization and hydrolysis. According to the process of the present invention, (2R)-2-propyloctanoic acid can be produced by less steps as compared with the conventional method without a dangerous reaction.

Abstract: Indole derivatives represented by formula (I) wherein all symbols represent the same as that in specification), production methods thereof, and DP receptor antagonist comprising them as active ingredients. Since the compounds of formula (I) binds and antagonizes to DP receptor, they are useful for the prevention and/or treatment against allergic diseases, diseases accompanied with itching, secondary diseases generated by behaviors caused by itching, inflammation, chronic obstructive pulmonary disease, ischemic reperfusion disorder, cerebrovascular disorder, pleuritis complicated by rheumatoid arthritis, ulcerative colitis.

Abstract: 2-Methylindole-4-acetic acid, which is represented by the formula (I) and is an intermediate for an important indole derivative as medicines; and a process for producing the compound and the synthetic intermediates.

Abstract: The consultant server and the consultation method are provided for fixing a user's fee and a rating for each service, notifying the user of the information, and allocating the user's fee among service providers based on the rating when a user obtains a service via the Internet. The consultant server includes a sending/receiving device by which evaluation information input by a user who has obtained a service, a information-processing device which fixes a user's fee and a rating for each service based on the evaluation information, a sending/receiving device which sends information about the above described user's fee and rating for each service to a user's personal computer and the like, an information-processing device which allocates user's fees for services among service providers based on the rating.