Patents by Inventor Tomoyuki Imai

Tomoyuki Imai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240002411
    Abstract: The present invention relates to a method for producing a radioactive zirconium-labeled complex that can realize a high labeling index in a reaction between a radioactive zirconium ion and a ligand compound. The production method of the present invention includes a step of reacting a radioactive zirconium ion with a ligand compound in a reaction solution containing water to coordinate the radioactive zirconium ion. This step is performed in a state where the pH of the reaction solution is in an acidic region. The reaction solution does not contain an organic solvent but contains a water-soluble organic compound having one or two sulfo groups or carboxy groups in its structure, separately from the ligand compound.
    Type: Application
    Filed: October 14, 2021
    Publication date: January 4, 2024
    Applicant: NIHON MEDI-PHYSICS CO., LTD.
    Inventors: Hideaki TAKEMORI, Hiroaki ICHIKAWA, Minoru KAWATANI, Akihiro IZAWA, Tomoyuki IMAI
  • Publication number: 20230390426
    Abstract: A method for producing a radioactive zirconium complex of the present invention includes a step of reacting a radioactive zirconium ion, a ligand compound containing DOTA or a DOTA derivative, and an additive such as hydroxybenzoic acid and a derivative thereof with one another in a reaction solution to form a radioactive zirconium complex. As the reaction solution, a reaction solution is used in which the amount of radioactivity of the radioactive zirconium ion is 60 MBq or more at the start of the reaction and the amount of radioactivity of the radioactive zirconium ion is 5 MBq or more per 1 nmol of the ligand compound at the start of the reaction.
    Type: Application
    Filed: October 14, 2021
    Publication date: December 7, 2023
    Applicant: NIHON MEDI-PHYSICS CO., LTD.
    Inventors: Tomoyuki IMAI, Hiroaki ICHIKAWA, Satoshi KISHIMOTO, Akihiro IZAWA
  • Publication number: 20230364275
    Abstract: A method for producing an 225Ac solution includes a step (I) of irradiating a 226Ra target with particles to generate two or more actinium radioisotopes (Ac) including at least 225Ac, a step (II) of dissolving the 226Ra target after the aforementioned step to obtain a solution (1), a step (III) of separating 226Ra and Ac contained in the solution (1) to obtain a solution (2), a step (IV) of allowing Ac contained in the solution (2) other than 225Ac to decay to obtain a solution (3), and a step (V) of separating Ra and Ac contained in the solution (3) to obtain a solution (4). The solution (4) is used to produce a medicine that contains, as an active ingredient, a conjugate between a chelating agent that has formed a complex with 225Ac, and a targeting agent.
    Type: Application
    Filed: July 10, 2023
    Publication date: November 16, 2023
    Applicants: NIHON MEDI-PHYSICS CO., LTD., NATIONAL INSTITUTES FOR QUANTUM SCIENCE AND TECHNOLOGY
    Inventors: Yoshio HONDA, Taku ITO, Jun ICHINOSE, Hiroaki ICHIKAWA, Tomoyuki IMAI, Kotaro NAGATSU, Hisashi SUZUKI
  • Patent number: 11752223
    Abstract: A method for producing an 225Ac solution includes a step (I) of irradiating a 226Ra target with particles to generate two or more actinium radioisotopes (Ac) including at least 225Ac, a step (II) of dissolving the 226Ra target after the aforementioned step to obtain a solution (1), a step (III) of separating 226Ra and Ac contained in the solution (1) to obtain a solution (2), a step (IV) of allowing Ac contained in the solution (2) other than 225Ac to decay to obtain a solution (3), and a step (V) of separating Ra and Ac contained in the solution (3) to obtain a solution (4). The solution (4) is used to produce a medicine that contains, as an active ingredient, a conjugate between a chelating agent that has formed a complex with 225Ac, and a targeting agent.
    Type: Grant
    Filed: July 20, 2022
    Date of Patent: September 12, 2023
    Assignees: NIHON MEDI-PHYSICS CO., LTD., NATIONAL INSTITUTES FOR QUANTUM SCIENCE AND TECHNOLOGY
    Inventors: Yoshio Honda, Taku Ito, Jun Ichinose, Hiroaki Ichikawa, Tomoyuki Imai, Kotaro Nagatsu, Hisashi Suzuki
  • Publication number: 20220370651
    Abstract: A method for producing an 225Ac solution includes a step (I) of irradiating a 226Ra target with particles to generate two or more actinium radioisotopes (Ac) including at least 225Ac, a step (II) of dissolving the 226Ra target after the aforementioned step to obtain a solution (1), a step (III) of separating 226Ra and Ac contained in the solution (1) to obtain a solution (2), a step (IV) of allowing Ac contained in the solution (2) other than 225Ac to decay to obtain a solution (3), and a step (V) of separating Ra and Ac contained in the solution (3) to obtain a solution (4). The solution (4) is used to produce a medicine that contains, as an active ingredient, a conjugate between a chelating agent that has formed a complex with 225Ac, and a targeting agent.
    Type: Application
    Filed: July 20, 2022
    Publication date: November 24, 2022
    Applicants: NIHON MEDI-PHYSICS CO., LTD., NATIONAL INSTITUTES FOR QUANTUM SCIENCE AND TECHNOLOGY
    Inventors: Yoshio HONDA, Taku ITO, Jun ICHINOSE, Hiroaki ICHIKAWA, Tomoyuki IMAI, Kotaro NAGATSU, Hisashi SUZUKI
  • Publication number: 20220259160
    Abstract: A method for producing a radioactive metal complex includes a step of allowing a radioactive metal to react with DOTA or a derivative thereof as a ligand in a reaction liquid to form a radioactive metal complex. The reaction liquid contains water, a buffer, and a water-soluble organic solvent. The radioactive metal is 89Zr or 225Ac. The ligand may have, in the structure thereof, a group to which a peptide is linked. The content of the water-soluble organic solvent in the reaction liquid is preferably 2% by volume or more and 50% by volume or less. The radioactive metal is preferably allowed to react with the ligand in the reaction liquid at 30° C. or higher and 80° C. or lower.
    Type: Application
    Filed: August 4, 2020
    Publication date: August 18, 2022
    Applicant: NIHON MEDI-PHYSICS CO., LTD.
    Inventors: Tomoyuki IMAI, Masato KIRIU, Akihiro IZAWA
  • Publication number: 20070021299
    Abstract: A catalyst for reacting hydrocarbon with steam according to the present invention, has a specific surface area of 40 to 300 m2/g, and comprises: a porous composite oxide carrier containing magnesium and aluminum; and nickel metal in the form of fine particles carried on the porous composite oxide carrier, and having a magnesium content of 5 to 55% by weight, calculated as Mg, based on the weight of the catalyst, an aluminum content of 5 to 35% by weight, calculated as Al, based on the weight of the catalyst, a nickel content of 1.2 to 60% by weight, calculated as Ni, based on the weight of the catalyst, and a total amount of magnesium, aluminum and nickel of 50 to 85% by weight, calculated as a sum of Mg, Al and Ni, based on the weight of the catalyst, the fine nickel metal particles having an average particle diameter of not more than 10 nm.
    Type: Application
    Filed: September 25, 2006
    Publication date: January 25, 2007
    Applicants: Hiroshima Industrial Promotion Organization, Toda Kogyo Corporation, Mitsubishi Heavy Industries, Ltd.
    Inventors: Katsuomi Takehira, Tetsuya Shishido, Hiroyuki Morioka, Naoya Kobayashi, Tsutomu Katamoto, Tomoyuki Imai, Kozo Iida, Toshinobu Yasutake
  • Publication number: 20060081811
    Abstract: Iron composite particles for purifying soil or ground water, comprise an iron component, at least one noble metal selected from the group consisting of ruthenium, rhodium and palladium, and carbon or aluminum, and having a noble metal content of 0.01 to 5.00% by weight and a particle diameter of 0.01 to 1.0 ?m. The iron composite particles and the purifying agent according to the present invention are capable of decomposing aliphatic organohalogen compounds such as dichloromethane, carbon tetrachloride, 1,2-dichloroethane, 1,1-dichloroethylene, cis-1,2-dichloroethylene, 1,1,1-trichloroethane, 1,1,2-trichloroethane, trichloroethylene, tetrachloroethylene, 1,3-dichloropropene or the like, and aromatic organohalogen compounds such as dioxins, PCB (polychlorinated biphenyl) or the like, which are contained in soil, ground water or waste water, at ordinary temperature in an efficient and economical manner.
    Type: Application
    Filed: March 7, 2005
    Publication date: April 20, 2006
    Applicant: TODA KOGYO CORPORATION
    Inventors: Toshiki Matsui, Tomoyuki Imai, Yasuhiko Fujii, Tomoko Okita, Kenji Okinaka, Masayuki Uegami, Osamu Okimoto, Junichi Kawano, Koji Kakuya
  • Publication number: 20040213720
    Abstract: The invention relates to a method for removing ammoniacal components of a flue gas that has been treated according to the SNCR method, wherein the method is characterized in that the flue gas is contacted at a temperature, that is at least 150° C. below that at which the SNCR method is carried out, with a ferro-oxidic catalyst having a specific surface area of at least 0.2 m2/g, measured according to the BET method. Preferably, the catalyst is added to the flue gas at a temperature of 700-400° C. of the gas in the flue channel.
    Type: Application
    Filed: June 4, 2004
    Publication date: October 28, 2004
    Inventors: Christian Wolf, Kai Keldenich, Thomas Marzi, Tetsuro Toda, Tomoyuki Imai
  • Patent number: 6800587
    Abstract: An iron compound catalyst for inhibiting the generation of dioxin contains iron oxide particles, iron oxide hydroxide particles or mixed particles having a catalytic activity capable of converting not less than 15% of carbon monoxide into carbon dioxide when 2.8×10−4 mol of iron oxide particles obtained by heat-treating the iron compound catalyst in air at a temperature of 800° C. for 15 minutes, are instantaneously contacted with 6.1×10−7 mol of carbon monoxide at a temperature of 250° C. at a space velocity (SV) of 42,400 h−1 in an inert gas atmosphere using a pulse catalytic reactor, the iron oxide particles or the iron oxide hydroxide particles have an average particle size of 0.01 to 2.0 &mgr;m, a BET specific surface area of 0.2 to 200 m2/g, a phosphorus content of not more than 0.02% by weight, a sulfur content of not more than 0.6% by weight and a sodium content of not more than 0.5% by weight.
    Type: Grant
    Filed: April 25, 2001
    Date of Patent: October 5, 2004
    Assignees: Toda Kogyo Corporation, Naikai Plant Kabushiki Kaisha
    Inventors: Tomoyuki Imai, Toshiki Matsui, Yasuhiko Fujii, Satoshi Hatakeyama, Kojiro Tsutsumi, Tomoko Okita, Hiroshi Inoue, Tatsuaki Baba, Masaki Ishihara, Takashi Okamura
  • Patent number: 6663840
    Abstract: The present invention relates to a process for treating a dioxin-containing exhaust gas which can inhibit the generation of dioxin occurring either in the course of cooling of the exhaust gas between a downstream portion subsequent to a combustion chamber and a dust collector or due to a memory effect upon low-temperature combustion in flues or dust collector at the start-up or shut-down of intermittent operation-type solid waste incinerators, without large-scale incineration facilities or plant renovation and equipment investment, and a composite catalyst composition for inhibiting the generation of dioxin, comprising an iron compound, an acid gas neutralizing agent and optionally an activated carbon.
    Type: Grant
    Filed: July 8, 2002
    Date of Patent: December 16, 2003
    Assignee: Toda Kogyo Corporation
    Inventors: Tomoyuki Imai, Satoshi Hatakeyama, Toshiki Matsui, Yasuhiko Fujii, Tomoko Okita, Hiroshi Inoue, Masaki Ishihara, Masayuki Ukita
  • Publication number: 20030047488
    Abstract: A catalyst for reacting hydrocarbon with steam according to the present invention, has a specific surface area of 40 to 300 m2/g, and comprises:
    Type: Application
    Filed: August 19, 2002
    Publication date: March 13, 2003
    Inventors: Katsuomi Takehira, Tetsuya Shishido, Hiroyuki Morioka, Naoya Kobayashi, Tsutomu Katamoto, Tomoyuki Imai, Kozo Iida, Toshinobu Yasutake
  • Publication number: 20020198102
    Abstract: The present invention relates to a process for treating a dioxin-containing exhaust gas which can inhibit the generation of dioxin occurring either in the course of cooling of the exhaust gas between a downstream portion subsequent to a combustion chamber and a dust collector or due to a memory effect upon low-temperature combustion in flues or dust collector at the start-up or shut-down of intermittent operation-type solid waste incinerators, without large-scale incineration facilities or plant renovation and equipment investment, and a composite catalyst composition for inhibiting the generation of dioxin, comprising an iron compound, an acid gas neutralizing agent and optionally an activated carbon.
    Type: Application
    Filed: July 8, 2002
    Publication date: December 26, 2002
    Applicant: Toda Kogyo Corporation
    Inventors: Tomoyuki Imai, Satoshi Hatakeyama, Toshiki Matsui, Yasuhiko Fujii, Tomoko Okita, Hiroshi Inoue, Masaki Ishihara, Masayuki Ukita
  • Patent number: 6476112
    Abstract: Calcium-iron oxide composite particles of the present invention have a BET specific surface area of 1 to 100 m2/g and containing iron atom in an amount of 1 to 50 moles based on 100 moles of calcium atom, the iron atom of not less than 50% based on the total amount of iron atom contained in said calcium-iron oxide composite particles being bonded with calcium atom for forming a calcium-iron ferrite phase. A hydrogen chloride-scavenger comprising the calcium-iron oxide composite particles, is capable of effectively capturing harmful hydrogen chloride generated by thermal decomposition or combustion of chorine-containing resin molded products upon fire or incineration thereof, and fixing the hydrogen chloride as stable calcium chloride or the like.
    Type: Grant
    Filed: January 12, 2001
    Date of Patent: November 5, 2002
    Assignee: Toda Kogyo Corporation
    Inventors: Toshiki Matsui, Masaru Isoai, Yasuhiko Fujii, Satoshi Hatakeyama, Tomoko Okita, Tomoyuki Imai
  • Patent number: 6459012
    Abstract: A process for treating an organohalogen compound-containing soil or ash of the present invention, comprises: mixing the organohalogen compound-containing soil or ash with an organohalogen compound-decomposition catalyst composed of a composite catalyst comprising an amine compound and iron compound particles, and having an average particle size of 0.01 to 2.0 &mgr;m, a phosphorus content of not more than 0.02% by weight, a sulfur content of not more than 0.3% by weight and a sodium content of not more than 0.3% by weight; and having an apparent density (&rgr;a) of not more than 0.8 g/ml and a catalytic activity capable of decomposing not less than 50% by weight of monochlorobenzene; and heat-treating the obtained mixture at a temperature of 150 to 600° C. The method for treating an organohalogen compound-containing soil or ash in order to effectively decompose dioxins and dioxin precursors such as aromatic organohalogen compounds or aliphatic organohalogen compounds, e.g.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: October 1, 2002
    Assignee: Toda Kogyo Corporation
    Inventors: Tomoyuki Imai, Satoshi Hatakeyama, Toshiki Matsui, Yasuhiko Fujii, Tomoko Okita, Toshiyuki Hakata
  • Patent number: 6436868
    Abstract: The present invention relates to a process for treating a dioxin-containing exhaust gas which can inhibit the generation of dioxin occurring either in the course of cooling of the exhaust gas between a downstream portion subsequent to a combustion chamber and a dust collector or due to a memory effect upon low-temperature combustion in flues or dust collector at the start-up or shut-down of intermittent operation-type solid waste incinerators, without large-scale incineration facilities or plant renovation and equipment investment, and a composite catalyst composition for inhibiting the generation of dioxin, comprising an iron compound, an acid gas neutralizing agent and optionally an activated carbon.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: August 20, 2002
    Assignee: Toda Kogyo Corporation
    Inventors: Tomoyuki Imai, Satoshi Hatakeyama, Toshiki Matsui, Yasuhiko Fujii, Tomoko Okita, Hiroshi Inoue, Masaki Ishihara, Masayuki Ukita
  • Publication number: 20020103284
    Abstract: A resin composition comprising (a) 100 parts by weight of a thermoplastic resin containing nitrogen atom(s) in structural units thereof; and (b) 0.1 to 20 parts by weight of an iron compound catalyst comprising at least one iron oxide-based compound selected from the group consisting of iron oxide hydroxide particles or iron oxide particles, which has an average particle size of 0.05 to 2.0 &mgr;m; and has a specific oxidation activity.
    Type: Application
    Filed: February 5, 2002
    Publication date: August 1, 2002
    Inventors: Suminori Tanaka, Toshiaki Shimuzu, Toshiki Matsui, Tomoyuki Imai
  • Publication number: 20020059818
    Abstract: A process for treating an organohalogen compound-containing soil or ash of the present invention, comprises:
    Type: Application
    Filed: September 17, 2001
    Publication date: May 23, 2002
    Inventors: Tomoyuki Imai, Satoshi Hatakeyama, Toshiki Matsui, Yasuhiko Fujii, Tomoko Okita, Toshiyuki Hakata
  • Patent number: 6365282
    Abstract: A resin composition comprising (a) 100 parts by weight of a thermoplastic resin containing nitrogen atom(s) in structural units thereof; and (b) 0.1 to 20 parts by weight of an iron compound catalyst comprising at least one iron oxide-based compound selected from the group consisting of iron oxide hydroxide particles or iron oxide particles, which has an average particle size of 0.05 to 2.0 &mgr;m; and has a specific oxidation activity. Such a resin composition is inhibited from generating hydrocyanic acid upon the combustion, though the composition contains nitrogen atom(s) in structural units thereof.
    Type: Grant
    Filed: September 21, 2000
    Date of Patent: April 2, 2002
    Assignee: Toda Kogyo Corporation
    Inventors: Suminori Tanaka, Toshiaki Shimuzu, Toshiki Matsui, Tomoyuki Imai
  • Publication number: 20010031235
    Abstract: An iron compound catalyst for inhibiting the generation of dioxin of the present invention, comprise iron oxide particles, iron oxide hydroxide particles or mixed particles thereof having a catalytic activity capable of converting not less than 15% of carbon monoxide into carbon dioxide when 2.8×10−4 mol of iron oxide particles obtained by heat-treating said iron compound catalyst in air at a temperature of 800° C. for 15 minutes, are instantaneously contacted with 6.1×10−7 mol of carbon monoxide at a temperature of 250° C. at a space velocity (SV) of 42,400 h−1 in an inert gas atmosphere using a pulse catalytic reactor, said iron oxide particles or said iron oxide hydroxide particles having an average particle size of 0.01 to 2.0 &mgr;m, a BET specific surface area of 0.2 to 200 m2/g, a phosphorus content of not more than 0.02% by weight, a sulfur content of not more than 0.6% by weight and a sodium content of not more than 0.5% by weight.
    Type: Application
    Filed: April 25, 2001
    Publication date: October 18, 2001
    Applicant: Toda Kogyo Corporation
    Inventors: Tomoyuki Imai, Toshiki Matsui, Yasuhiko Fujii, Satoshi Hatakeyama, Kojiro Tsutsumi, Tomoko Okita, Hiroshi Inoue, Tatsuaki Baba, Masaki Ishihara, Takashi Okamura