Patents by Inventor Tomoyuki NOSE
Tomoyuki NOSE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11927599Abstract: Included are: a main body including an installation part in which a cartridge housing a liquid for treating a test substance contained in a specimen is installed and a detector configured to detect the test substance treated with the liquid within the cartridge installed in the installation part; a lid part arranged rotatably on the main body about a shaft so as to open and close the installation part; a biasing part biasing the lid part in an opening direction; and a plurality of regulators each generating resistance against a biasing force in the opening direction at different timing during an opening motion of the lid part.Type: GrantFiled: January 25, 2021Date of Patent: March 12, 2024Assignees: JVCKENWOOD Corporation, SYSMEX CORPORATIONInventors: Masahiro Yamamoto, Shigeru Yokota, Hideki Samata, Tomoyuki Nose, Sayuri Tomoda
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Patent number: 11656223Abstract: In a method of detecting a test substance, a test substance is detected using a sample analysis cartridge supplied with a sample. The sample analysis cartridge includes: a passage part having a gas-phase space; and liquid containers communicating with the passage part through openings. The liquid containers include: a first liquid container containing a first liquid containing magnetic particles; and a second liquid container containing a second liquid containing a labeled substance. The magnetic particles are sequentially transported to the liquid containers through the gas-phase space in the passage part. Thus, the magnetic particles carry a complex of the test substance and the labeled substance. The test substance is detected based on the labeled substance in the complex.Type: GrantFiled: June 24, 2021Date of Patent: May 23, 2023Assignee: SYSMEX CORPORATIONInventors: Kazuyoshi Horii, Tomoyuki Nose, Takao Fujiwara, Tatsuya Kosako
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Patent number: 11511246Abstract: The present invention provides a cartridge, a detection method, and a detection device capable of stabilizing the liquid level of a sample accommodated in a chamber in a predetermined state. A cartridge 20, that is rotated around a rotating shaft 42 for detecting a target substance, is provided with a chamber 100 in which a sample containing a target substance is stored. The chamber 100 includes a first region 110 in which a sample is stored, a second region 120 disposed at a position closer to the rotating shaft 42 than the first region 110, and a protrusion 130 protruding from a position between the first region 110 and the second region 120 to the inner side of the chamber 100.Type: GrantFiled: September 27, 2018Date of Patent: November 29, 2022Assignee: SYSMEX CORPORATIONInventors: Yongjian Yang, Tomoyuki Nose, Sayuri Tomoda, Kazuyoshi Horii
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Patent number: 11480525Abstract: Disclosed is a chemiluminescence measurement apparatus that includes: a support member configured to support a cartridge for measuring a test substance contained in a specimen by chemiluminescence measurement; a motor configured to rotate the support member so as to rotate the cartridge such that a process required for the chemiluminescence measurement proceeds in the cartridge; and a light receiver configured to receive light generated by chemiluminescence in the cartridge that is supported by the support member rotated by the motor. The cartridge supported by the support member and a light receiving surface of the light receiver are disposed inside a dark space surrounded by a light-shielding portion, and the motor is disposed outside the dark space.Type: GrantFiled: June 29, 2017Date of Patent: October 25, 2022Assignee: SYSMEX CORPORATIONInventors: Sayuri Tomoda, Tomoyuki Nose, Noriaki Sasaki, Kazuyoshi Horii
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Patent number: 11327086Abstract: A sample measuring method of optically measuring a sample housed in a container in a sample measurement device, the method including: loading the container such that the container is shielded from light; starting to read information regarding a measurement to be performed on the sample in response to the loading the container; and measuring the sample based on the read information.Type: GrantFiled: November 30, 2018Date of Patent: May 10, 2022Assignee: SYSMEX CORPORATIONInventors: Tomoyuki Nose, Sayuri Tomoda, Yusuke Miida, Kazuyoshi Horii, Kenichiro Suzuki
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Patent number: 11266985Abstract: Disclosed is a liquid sealed cartridge in which a liquid injected through an inlet is previously sealed, and the liquid is transferred by a centrifugal force being applied by rotation, and the liquid sealed cartridge includes: a liquid storage portion configured to store the liquid; a bypass flow path having one end and the other end connected to the liquid storage portion, the bypass flow path having the inlet; and a transfer flow path into which the liquid is transferred from the liquid storage portion when the centrifugal force is applied.Type: GrantFiled: November 2, 2017Date of Patent: March 8, 2022Assignee: SYSMEX CORPORATIONInventors: Kazuyoshi Horii, Takao Fujiwara, Tomoyuki Nose
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Patent number: 11231373Abstract: A method according to one or more aspects may be a method of measuring a detection material contained in a sample by using a cartridge including: chambers each capable of housing at least one of the detection material and a reagent; and a path through which the detection material is transferred between the chambers. The method may include: moving at least one of the chambers and the path to a measurement position and an image capturing range by rotating the cartridge about a rotational shaft; measuring the detection material in the measurement position; and capturing an image of a monitoring target comprising at least one of the chambers and the path in the image capturing range.Type: GrantFiled: November 28, 2018Date of Patent: January 25, 2022Assignee: SYSMEX CORPORATIONInventors: Tomoyuki Nose, Yusuke Muda, Kanako Nagaoka, Noriyuki Narisada, Varun Nambigari
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Publication number: 20210318297Abstract: In a method of detecting a test substance, a test substance is detected using a sample analysis cartridge supplied with a sample. The sample analysis cartridge includes: a passage part having a gas-phase space; and liquid containers communicating with the passage part through openings. The liquid containers include: a first liquid container containing a first liquid containing magnetic particles; and a second liquid container containing a second liquid containing a labeled substance. The magnetic particles are sequentially transported to the liquid containers through the gas-phase space in the passage part. Thus, the magnetic particles carry a complex of the test substance and the labeled substance. The test substance is detected based on the labeled substance in the complex.Type: ApplicationFiled: June 24, 2021Publication date: October 14, 2021Applicant: SYSMEX CORPORATIONInventors: Kazuyoshi HORII, Tomoyuki NOSE, Takao FUJIWARA, Tatsuya KOSAKO
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Patent number: 11117135Abstract: Disclosed is a liquid-sealed cartridge in which a liquid is transferred by a centrifugal force generated when the liquid-sealed cartridge is rotated around a rotation shaft, including: a liquid storage portion configured to store the liquid therein; a seal having an outer peripheral portion connected to the liquid storage portion, the seal being configured to seal the liquid storage portion; a flow path connected to the liquid storage portion via the seal, through which the liquid in the liquid storage portion is transferred by the centrifugal force in a direction away from the rotation shaft, wherein, when the seal receives a pressing force, the seal is inclined in a pressing direction, with one portion of the outer peripheral portion thereof remaining connected with the liquid storage portion, and the other portion of the outer peripheral portion being separated from the liquid storage portion.Type: GrantFiled: October 27, 2017Date of Patent: September 14, 2021Assignees: Sysmex Corporation, ASTI CorporationInventors: Kazuyoshi Horii, Takao Fujiwara, Tomoyuki Nose, Yasunori Maekawa, Noriyuki Ogai, Yasuhiro Toda
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Patent number: 11099182Abstract: Disclosed is a detection apparatus that transfers magnetic particles through a plurality of chambers in a cartridge which includes the plurality of chambers and a channel connecting between the plurality of chambers, and that causes the magnetic particles to carry a complex of a test substance and a labelling substance, to detect the test substance on the basis of the labelling substance in the complex. The detection apparatus includes: a rotation mechanism configured to rotate the cartridge about a rotation shaft; a magnet configured to collect the magnetic particles in the chambers; a movement mechanism configured to move the magnet in a direction different from a circumferential direction of a circle in which the rotation shaft is centered; a detector configured to detect the test substance; and a controller programmed to control the rotation mechanism and the movement mechanism so as to transfer the magnetic particles from one of the chambers to another one of the chambers.Type: GrantFiled: June 29, 2017Date of Patent: August 24, 2021Assignee: Sysmex CorporationInventors: Kazuyoshi Horii, Tomoyuki Nose, Takao Fujiwara, Sayuri Tomoda, Yusuke Miida, Yasunori Maekawa, Noriaki Sasaki
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Publication number: 20210231696Abstract: Included are: a main body including an installation part in which a cartridge housing a liquid for treating a test substance contained in a specimen is installed and a detector configured to detect the test substance treated with the liquid within the cartridge installed in the installation part; a lid part arranged rotatably on the main body about a shaft so as to open and close the installation part; a biasing part biasing the lid part in an opening direction; and a plurality of regulators each generating resistance against a biasing force in the opening direction at different timing during an opening motion of the lid part.Type: ApplicationFiled: January 25, 2021Publication date: July 29, 2021Inventors: Masahiro Yamamoto, Shigeru Yokota, Hideki Samata, Tomoyuki Nose, Sayuri Tomoda
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Patent number: 11073514Abstract: In a method of detecting a test substance, a test substance is detected using a sample analysis cartridge supplied with a sample. The sample analysis cartridge includes: a passage part having a gas-phase space; and liquid containers communicating with the passage part through openings. The liquid containers include: a first liquid container containing a first liquid containing magnetic particles; and a second liquid container containing a second liquid containing a labeled substance. The magnetic particles are sequentially transported to the liquid containers through the gas-phase space in the passage part. Thus, the magnetic particles carry a complex of the test substance and the labeled substance. The test substance is detected based on the labeled substance in the complex.Type: GrantFiled: September 19, 2019Date of Patent: July 27, 2021Assignee: SYSMEX CORPORATIONInventors: Kazuyoshi Horii, Tomoyuki Nose, Takao Fujiwara, Tatsuya Kosako
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Publication number: 20210148905Abstract: Disclosed is a detection apparatus that transfers magnetic particles through a plurality of chambers in a cartridge which includes the plurality of chambers and a channel connecting between the plurality of chambers, and that causes the magnetic particles to carry a complex of a test substance and a labelling substance, to detect the test substance on the basis of the labelling substance in the complex. The detection apparatus includes: a rotation mechanism configured to rotate the cartridge about a rotation shaft; a magnet configured to collect the magnetic particles in the chambers; a movement mechanism configured to move the magnet in a direction different from a circumferential direction of a circle in which the rotation shaft is centered; a detector configured to detect the test substance; and a controller programmed to control the rotation mechanism and the movement mechanism so as to transfer the magnetic particles from one of the chambers to another one of the chambers.Type: ApplicationFiled: January 29, 2021Publication date: May 20, 2021Inventors: Kazuyoshi HORII, Tomoyuki Nose, Takao Fujiwara, Sayuri Tomoda, Yusuke Miida, Yasunori Maekawa, Noriaki Sasaki
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Publication number: 20200011861Abstract: In a method of detecting a test substance, a test substance is detected using a sample analysis cartridge supplied with a sample. The sample analysis cartridge includes: a passage part having a gas-phase space; and liquid containers communicating with the passage part through openings. The liquid containers include: a first liquid container containing a first liquid containing magnetic particles; and a second liquid container containing a second liquid containing a labeled substance. The magnetic particles are sequentially transported to the liquid containers through the gas-phase space in the passage part. Thus, the magnetic particles carry a complex of the test substance and the labeled substance. The test substance is detected based on the labeled substance in the complex.Type: ApplicationFiled: September 19, 2019Publication date: January 9, 2020Applicant: SYSMEX CORPORATIONInventors: Kazuyoshi HORII, Tomoyuki NOSE, Takao FUJIWARA, Tatsuya KOSAKO
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Patent number: 10473652Abstract: In a method of detecting a test substance, a test substance is detected using a sample analysis cartridge supplied with a sample. The sample analysis cartridge includes: a passage part having a gas-phase space; and liquid containers communicating with the passage part through openings. The liquid containers include: a first liquid container containing a first liquid containing magnetic particles; and a second liquid container containing a second liquid containing a labeled substance. The magnetic particles are sequentially transported to the liquid containers through the gas-phase space in the passage part. Thus, the magnetic particles carry a complex of the test substance and the labeled substance. The test substance is detected based on the labeled substance in the complex.Type: GrantFiled: March 25, 2016Date of Patent: November 12, 2019Assignee: SYSMEX CORPORATIONInventors: Kazuyoshi Horii, Tomoyuki Nose, Takao Fujiwara, Tatsuya Kosako
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Patent number: 10393765Abstract: Disclosed is a measurement apparatus including: a support mechanism configured to support a cartridge in which a chamber is formed, the chamber being configured to store a measurement sample that generates light an intensity of which varies depending on an amount of a test substance; a photodetector configured to detect the light generated from the measurement sample stored in the chamber; and a reflection member provided between the photodetector and the cartridge supported by the support mechanism, the reflection member having an inner face, the reflection member being configured to reflect, at the inner face, the light generated from the measurement sample stored in the chamber, and guide the light to the photodetector, wherein the reflection member is configured to have an area surrounded by the inner face, the area decreasing from a side where the cartridge supported by the support mechanism is provided toward a side where the photodetector is provided.Type: GrantFiled: June 29, 2017Date of Patent: August 27, 2019Assignee: SYSMEX CORPORATIONInventors: Takao Fujiwara, Kazuyoshi Horii, Tatsuya Kosako, Tomoyuki Nose, Sayuri Tomoda
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Publication number: 20190162670Abstract: A method according to one or more aspects may be a method of measuring a detection material contained in a sample by using a cartridge including: chambers each capable of housing at least one of the detection material and a reagent; and a path through which the detection material is transferred between the chambers. The method may include: moving at least one of the chambers and the path to a measurement position and an image capturing range by rotating the cartridge about a rotational shaft; measuring the detection material in the measurement position; and capturing an image of a monitoring target comprising at least one of the chambers and the path in the image capturing range.Type: ApplicationFiled: November 28, 2018Publication date: May 30, 2019Applicant: SYSMEX CORPORATIONInventors: Tomoyuki NOSE, Yusuke MIIDA, Kanako NAGAOKA, Noriyuki NARISADA, Varun NAMBIGARI
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Publication number: 20190162740Abstract: A sample measuring method of optically measuring a sample housed in a container in a sample measurement device, the method including: loading the container such that the container is shielded from light; starting to read information regarding a measurement to be performed on the sample in response to the loading the container; and measuring the sample based on the read information.Type: ApplicationFiled: November 30, 2018Publication date: May 30, 2019Applicant: SYSMEX CORPORATIONInventors: Tomoyuki NOSE, Sayuri TOMODA, Yusuke MIIDA, Kazuyoshi HORII, Kenichiro SUZUKI
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Publication number: 20190099728Abstract: The present invention provides a cartridge, a detection method, and a detection device capable of stabilizing the liquid level of a sample accommodated in a chamber in a predetermined state. A cartridge 20, that is rotated around a rotating shaft 42 for detecting a target substance, is provided with a chamber 100 in which a sample containing a target substance is stored. The chamber 100 includes a first region 110 in which a sample is stored, a second region 120 disposed at a position closer to the rotating shaft 42 than the first region 110, and a protrusion 130 protruding from a position between the first region 110 and the second region 120 to the inner side of the chamber 100.Type: ApplicationFiled: September 27, 2018Publication date: April 4, 2019Inventors: Yongjian Yang, Tomoyuki Nose, Sayuri Tomoda, Kazuyoshi Horii
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Publication number: 20180126377Abstract: Disclosed is a liquid sealed cartridge in which a liquid injected through an inlet is previously sealed, and the liquid is transferred by a centrifugal force being applied by rotation, and the liquid sealed cartridge includes: a liquid storage portion configured to store the liquid; a bypass flow path having one end and the other end connected to the liquid storage portion, the bypass flow path having the inlet; and a transfer flow path into which the liquid is transferred from the liquid storage portion when the centrifugal force is applied.Type: ApplicationFiled: November 2, 2017Publication date: May 10, 2018Inventors: Kazuyoshi HORII, Takao FUJIWARA, Tomoyuki NOSE