Patents by Inventor Tomoyuki Sako
Tomoyuki Sako has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8889120Abstract: A method for producing bacteria belonging to the genus Bifidobacterium having excellent viability even under various conditions with different environmental factors, novel bacteria belonging to the genus Bifidobacterium obtained by the method, and a method for detecting the bacteria are provided. By subculturing and storing bacteria belonging to the genus Bifidobacterium alternately in systems under conditions with different environmental factors, the bacteria belonging to the genus Bifidobacterium exhibiting excellent viability under all the conditions used for the alternate subculturing and storing can be produced.Type: GrantFiled: February 21, 2011Date of Patent: November 18, 2014Assignee: Kabushiki Kaisha Yakult HonshaInventors: Tomoyuki Sako, Mika Miura, Yasuhisa Shimakawa, Koji Miyazaki, Junji Fujimoto, Koichi Watanabe
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Patent number: 8404823Abstract: The invention provides a gene encoding a protein selected from among the following proteins (a) to (c): (a) a protein having any of the amino acid sequences of SEQ ID NOs: 2, 4, 6, 8, 10, 12, 14, 16, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, and 108; (b) a protein which has an amino acid sequence equivalent to any of the amino acid sequences of (a), except that one to several amino acid residues are deleted, substituted, or added, and which exhibits cytokine production regulatory activity; and (c) a protein which has an amino acid sequence having 90% or higher identity to any of the amino acid sequences of (a), and which exhibits cytokine production regulatory activity, as well as a gene useful for regulating cytokine production and use of the gene.Type: GrantFiled: October 26, 2007Date of Patent: March 26, 2013Assignee: Kabushiki Kaisha Yakult HonshaInventors: Tomoyuki Sako, Emi Yasuda, Masaki Serata, Satoshi Matsumoto, Kan Shida
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Patent number: 8379640Abstract: An internetwork device comprises a receiving module, an inter-device packet transfer interface, an inter-device packet transfer controller, an address translation module, and a transmission module. The receiving module receives a packet from a first network. The inter-device packet transfer interface carries out inter-device packet transfer involving transfer of a packet to or from another internetwork device. The inter-device packet transfer controller controls the inter-device packet transfers such that multiple fragmented packets created from a same original packet are collected by the same internetwork device, the fragmented packets being packets created by dividing a single original packet into multiple parts. The address translation module translates between a local address used within a specific network and a global address used across multiple networks, for at least one of a source address and a destination address of a packet.Type: GrantFiled: June 16, 2010Date of Patent: February 19, 2013Assignee: ALAXALA Networks CorporationInventors: Masataka Ichihashi, Shinji Katsume, Tomoyuki Sako
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Publication number: 20120329059Abstract: A method for producing bacteria belonging to the genus Bifidobacterium having excellent viability even under various conditions with different environmental factors, novel bacteria belonging to the genus Bifidobacterium obtained by the method, and a method for detecting the bacteria are provided. By subculturing and storing bacteria belonging to the genus Bifidobacterium alternately in systems under conditions with different environmental factors, the bacteria belonging to the genus Bifidobacterium exhibiting excellent viability under all the conditions used for the alternate subculturing and storing can be produced.Type: ApplicationFiled: February 21, 2011Publication date: December 27, 2012Applicant: KABUSHIKI KAISHA YAKULT HONSHAInventors: Tomoyuki Sako, Mika Miura, Yasuhisa Shimakawa, Koji Miyazaki, Junji Fujimoto, Koichi Watanabe
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Publication number: 20120021418Abstract: To provide a gene useful for imparting oxygen resistance to a microorganism and use of the gene. The oxygen-resistance-imparting gene encoding a protein selected from among the following proteins (a) to (c): (a) a protein having the amino acid sequence of SEQ ID NO: 2 or 6; (b) a protein which has an amino acid sequence equivalent to the amino acid sequence of (a), except that one to several amino acid residues are deleted, substituted, or added, and which exhibits oxygen-resistance-imparting activity; and (c) a protein which has an amino acid sequence having an identity of 85% or higher to the amino acid sequence of (a), and which exhibits oxygen-resistance-imparting activity.Type: ApplicationFiled: June 12, 2009Publication date: January 26, 2012Applicant: Kabushiki Kaisha Yakult HonshaInventors: Masaki Serata, Tomoyuki Sako
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Publication number: 20100322247Abstract: An internetwork device comprises a receiving module, an inter-device packet transfer interface, an inter-device packet transfer controller, an address translation module, and a transmission module. The receiving module receives a packet from a first network. The inter-device packet transfer interface carries out inter-device packet transfer involving transfer of a packet to or from another internetwork device. The inter-device packet transfer controller controls the inter-device packet transfers such that multiple fragmented packets created from a same original packet are collected by the same internetwork device, the fragmented packets being packets created by dividing a single original packet into multiple parts. The address translation module translates between a local address used within a specific network and a global address used across multiple networks, for at least one of a source address and a destination address of a packet.Type: ApplicationFiled: June 16, 2010Publication date: December 23, 2010Inventors: Masataka ICHIHASHI, Shinji Katsume, Tomoyuki Sako
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Publication number: 20100144551Abstract: The invention provides a gene encoding a protein selected from among the following proteins (a) to (c): (a) a protein having any of the amino acid sequences of SEQ ID NOs: 2, 4, 6, 8, 10, 12, 14, 16, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, and 108; (b) a protein which has an amino acid sequence equivalent to any of the amino acid sequences of (a), except that one to several amino acid residues are deleted, substituted, or added, and which exhibits cytokine production regulatory activity; and (c) a protein which has an amino acid sequence having 90% or higher identity to any of the amino acid sequences of (a), and which exhibits cytokine production regulatory activity, as well as a gene useful for regulating cytokine production and use of the gene.Type: ApplicationFiled: October 26, 2007Publication date: June 10, 2010Applicant: Kabushiki Kaisha Yakult HonshaInventors: Tomoyuki Sako, Emi Yasuda, Masaki Serata, Satoshi Matsumoto, Kan Shida
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Patent number: 6319692Abstract: Methods for transferring a foreign gene into a host chromosome by integrating the foreign gene into a vector by utilizing a lysogenic phage, for the purpose of deleting unnecessary genes derived from the vector, except for the foreign gene.Type: GrantFiled: December 22, 1998Date of Patent: November 20, 2001Assignee: Kabushiki Kaisha Yakult HonshaInventors: Mariko Kadota, Mayumi Kiwaki, Saeko Sawaki, Yukio Shirasawa, Harue Sone, Tomoyuki Sako
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Patent number: 5475089Abstract: A thrombolytic peptide composed of 136 amino acids residues, which has little problems of antigenicity and is efficacious in only small doses as compared with staphylokinase (SAK). This peptide is obtained by cleaving amino acids or peptides which do not affect the activity of SAK by using a trypsin protease. In particular, SAK-11, which is obtained by cleaving a peptide composed of ten amino acid residues at the N-terminal of SAK, is superior to SAK in the fibrinolysis, plasminogen activation, and fibrin specificity.Type: GrantFiled: June 14, 1993Date of Patent: December 12, 1995Assignee: Kabushiki Kaisha Yakult HonshaInventors: Osamu Matsuo, Masashi Sakai, Kisaku Shimura, Hiroshi Sansawa, Tsunekazu Watanabe, Tsuneo Matsumoto, Yoshiyuki Shishido, Shusuke Hashimoto, Teruo Yokokura, Masaharu Onoue, Tomoyuki Sako
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Patent number: 4532211Abstract: Novel coliform bacillus useful for industrial production of staphylokinase, a fibrinolytic enzyme, and process for the production of staphylokinase using said microbe are provided. The novel microbe comprises a recombinant DNA, carrying genetic information for the production of staphylokinase, said genetic information being DNA derived from a temperate phage DNA of Staphylococcus aureus.Type: GrantFiled: October 15, 1982Date of Patent: July 30, 1985Assignee: Kabushiki Kaisha Yakult HonshaInventors: Tomoyuki Sako, Saeko Sawaki, Toshizo Sakurai, Masahiko Mutai, Isamu Kondo