Abstract: To provide a technique capable of handling quantitative data in a spectrum type microparticle measurement device without causing deterioration of the SNR. The present technology provides a microparticle measurement spectrometer including: a spectroscopic element that disperses light emitted from microparticles flowing through a flow path; and a photoelectric conversion array that has a plurality of light receiving elements having different detection wavelength ranges and converts optical information obtained by the light receiving elements into electrical information, in which the photoelectric conversion array has a uniform output of all channels when light with which the amount of light per unit wavelength becomes same is incident.

Abstract: To provide a technique capable of handling quantitative data in a spectrum type microparticle measurement device without causing deterioration of the SNR. The present technology provides a microparticle measurement spectrometer including a spectroscopic element that disperses light emitted from microparticles flowing through a flow path, and a photoelectric conversion array that has a plurality of light receiving elements having different detection wavelength ranges and converts optical information obtained by the light receiving elements into electrical information, in which the photoelectric conversion array has a uniform output of all channels when light with which the amount of light per unit wavelength becomes same is incident.

Abstract: An object of the present technology is to provide an information processing system that automatically executes panel design. The present technology provides an information processing system including: a fluorochrome database that holds fluorescence signal data of a fluorochrome associated with measuring instrument information; a reagent database that holds correspondence information regarding a correspondence between a reagent and the fluorochrome; and an information processing device that acquires the fluorescence signal data of the fluorochrome corresponding to the reagent from the fluorochrome database using the correspondence information regarding the reagent in the reagent database identified on the basis of input measurement target information and performs information processing using the fluorescence signal data of the fluorochrome.

Abstract: A main object of the present technology is to provide a technique for automatically proposing a better combination of fluorochrome-labeled antibodies. The present technology provides an information processing apparatus including a processing unit that generates a combination list of fluorophores for a biomolecule on the basis of an expression level category obtained by classifying a plurality of biomolecules used for analysis of a sample on the basis of an expression level in the sample, a brightness category obtained by classifying a plurality of fluorophores usable for analysis of the sample on the basis of brightness, correlation information between the plurality of fluorophores, and expression relationship information of the plurality of biomolecules, in which the processing unit selects a fluorophore to be assigned to the biomolecule in the combination list from fluorophores belonging to a brightness category associated with an expression level category to which the biomolecule belongs.

Abstract: A main object of the present technology is to provide a technique for automatically proposing a better combination of fluorochrome-labeled antibodies. The present technology provides an information processing apparatus including a processing unit that generates a combination list of phosphors with respect to biomolecules on the basis of expression level categories in which a plurality of biomolecules to be used for analysis of a sample is classified on the basis of expression levels in the sample, brightness categories in which a plurality of phosphors usable for the analysis of the sample is classified on the basis of brightness, and correlation information between the plurality of phosphors, in which the processing unit selects the phosphors to be allocated to the biomolecules in the combination list from phosphors belonging to a brightness category associated with an expression level category to which the biomolecules belong.

Abstract: A suitable fluorescence separation method is set according to an object to be measured. An information processing device according to an embodiment includes a separation unit (14) that calculates, from a fluorescence signal measured from a biological sample labeled with one or more fluorescent dyes, fluorescence intensities of one or more fluorescent beams and an autofluorescent beam emitted from the one or more fluorescent dyes and the biological sample, respectively, by an arithmetic operation using a least squares method using a fluorescence spectrum reference of each of the fluorescent dyes and an autofluorescence spectrum of the biological sample. In the arithmetic operation using the least squares method, an upper limit value and a lower limit value of the fluorescence intensity are set for each of the one or more fluorescent beams and the autofluorescent beam.

Abstract: A main object of the present technology is to provide a technology for automatically presenting a better combination of fluorescent markers. The present technology provides an information processing system including an information processing device that includes a calculation processing unit that calculates an objective function regarding a combination of a biomolecule, the biomolecule being a labeling target in a sample, with a labeling phosphor, on the basis of first data listing information on the biomolecule, and second data listing information on the labeling phosphor, and an assignment information output unit that outputs information on assignment of the labeling phosphors to respective biomolecules, the information being generated on the basis of combination information acquired from a combinatorial optimization processing unit on the basis of a coefficient of the objective function.

Abstract: The fine particle measurement apparatus according to the present technology includes a detection section, a multiplication factor setting section, a correction factor calculation section, and a spectrum generation section. The detection section has a plurality of detectors for detecting light from fine particles. The multiplication factor setting section sets a multiplication factor for each of the plurality of detectors. The correction factor calculation section calculates a correction factor on the basis of the set multiplication factor. The spectrum generation section generates spectral data by correcting a value detected by the detector, with the calculated correction factor.

Abstract: A microparticle analysis device (1) is provided with a light source (16), a two-dimensional photoelectric conversion sensor (28), and a calculation unit (10C). The light source (16) irradiates a microparticle (M) flowing in a flow path (14C) with excitation light (L1). The two-dimensional photoelectric conversion sensor (28) receives fluorescence emitted from the microparticle (M) by a light receiving surface (30) including a plurality of light reception units (32) arranged two-dimensionally, and acquires data of a fluorescence signal including stored charge values of the plurality of light reception units (32), respectively. The calculation unit (10C) calculates an evaluation value including an area that is a total value of a plurality of stored charge values included in the data of the fluorescence signal.

Abstract: To provide a technique capable of handling quantitative data in a spectrum type microparticle measurement device without causing deterioration of the SNR. The present technology provides a microparticle measurement spectrometer including: a spectroscopic element that disperses light emitted from microparticles flowing through a flow path; and a photoelectric conversion array that has a plurality of light receiving elements having different detection wavelength ranges and converts optical information obtained by the light receiving elements into electrical information, in which the photoelectric conversion array has a uniform output of all channels when light with which the amount of light per unit wavelength becomes same is incident.

Abstract: An information processing device includes a statistical processing unit that performs statistical processing for a group of spectra obtained by applying light to a group of microparticles that exhibit one response property with respect to light, and on a basis of a result of the statistical processing, exclude a spectrum indicating an outlier from the group of spectra, and a reference spectrum calculation unit that calculates a reference spectrum using the group of spectra from which the spectrum indicating the outlier has been excluded.

Abstract: To provide a cell evaluation device capable of evaluating cells and a secretory substance emitted from the cells accurately and precisely. Provided is a cell evaluation device including a first capturing unit that captures a secretory substance secreted by cells, and an image acquisition unit that acquires an image obtained by imaging observation light of the cells and light emitted from a luminescent substance bonded to the secretory substance, in which the image acquisition unit and the first capturing unit are disposed in this order, and the image acquisition unit acquires position information for the cells and the secretory substance.

Abstract: Provided is a fine particle measurement apparatus that offers improved spectral separation capability with reduced noise. The fine particle measurement apparatus according to the present technology includes a detection section, a multiplication factor setting section, a correction factor calculation section, and a spectrum generation section. The detection section has a plurality of detectors for detecting light from fine particles. The multiplication factor setting section sets a multiplication factor for each of the plurality of detectors. The correction factor calculation section calculates a correction factor on the basis of the set multiplication factor. The spectrum generation section generates spectral data by correcting a value detected by the detector, with the calculated correction factor.

Abstract: [Object] To increase the accuracy of a reference spectrum. [Solution] An information processing device includes: a statistical processing unit configured to perform statistical processing for a group of spectra obtained by applying light to a group of microparticles that exhibit one response property with respect to light, and on a basis of a result of the statistical processing, exclude a spectrum indicating an outlier from the group of spectra; and a reference spectrum calculation unit configured to calculate a reference spectrum using the group of spectra from which the spectrum indicating the outlier has been excluded.

Abstract: Provided is a cell determination device including a classification unit configured to classify individual cells based on one of a relaxation strength, a relaxation frequency, and low-frequency conductance obtained from a complex dielectric constant spectrum of the cells.

Abstract: Provided is a blood condition analysis device, a blood condition analysis system, a blood condition analysis method, and a program, according to which the coagulation system or fibrinolysis system of blood can be accurately evaluated from electrical characteristics. In a blood condition analysis device, an analysis unit is provided for evaluating, with respect to two or more blood samples adjusted from one blood specimen and having different drug types or concentrations, the influence of the drug or a factor in the blood on the coagulation system or fibrinolysis system of the blood on the basis of data of time-dependent changes in electrical characteristics measured at a specific frequency or frequency band.

Abstract: Provided is a cell determination device including a classification unit configured to classify individual cells based on one of a relaxation strength, a relaxation frequency, and low-frequency conductance obtained from a complex dielectric constant spectrum of the cells.

Abstract: Disclosed herein is a dielectric cytometric apparatus capable of analyzing cells and sorting the cells without adopting an optical analysis method and provides a dielectric cytometric cell sorting method for the apparatus. A stenosis channel allowing a single cell to flow is created on a cell injection section of a micro flow channel device used as a portion of the dielectric cytometric apparatus. A pair of measurement electrodes is created on the stenosis channel and an analyzer connected to the measurement electrodes measures the complex dielectric constant of for every cell passing through the stenosis channel. A electric-field application section provided on the downstream side of the stenosis channel applies an electric field for changing the flow of the cells inside a flow channel on the basis of information on the measured complex dielectric constants so that the cells can be sorted by making use of branch channels.

Abstract: Disclosed herein is a dielectric cytometric apparatus capable of analyzing cells and sorting the cells without adopting an optical analysis method and provides a dielectric cytometric cell sorting method for the apparatus. A stenosis channel allowing a single cell to flow is created on a cell injection section of a micro flow channel device used as a portion of the dielectric cytometric apparatus. A pair of measurement electrodes is created on the stenosis channel and an analyzer connected to the measurement electrodes measures the complex dielectric constant of for every cell passing through the stenosis channel. A electric-field application section provided on the downstream side of the stenosis channel applies an electric field for changing the flow of the cells inside a flow channel on the basis of information on the measured complex dielectric constants so that the cells can be sorted by making use of branch channels.

Abstract: A terahertz spectrometer includes: a terahertz-wave generating element; an elliptical mirror; an optical lens configured to apply a terahertz wave generated by the terahertz-wave generating element, obliquely to a focusing plane of a first focus of the elliptical mirror; and a terahertz-wave detecting element arranged at a second focus of the elliptical mirror.