Patents by Inventor Ton Vries

Ton Vries has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chiral salt resolution
    Patent number: 7432370
    Abstract: The present application discloses compounds of the formula wherein R2 and R3 are as defined herein. The present application further discloses certain pyrrolol[2,3-d]pyrimidine compounds having the 3R,4R stereochemical configuration shown above. Corresponding pharmaceutical compositions and methods for the treatment or prevention of a disorder or condition selected from organ transplant rejection, xeno transplantation, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, Crohn's disease, Alzheimer's disease, leukemia and other autoimmune diseases are also disclosed.
    Type: Grant
    Filed: June 15, 2004
    Date of Patent: October 7, 2008
    Assignee: Pfizer Inc.
    Inventors: Glenn E. Wilcox, Mark E. Flanagan, Michael J. Munchhof, Ton Vries, Christian Koecher
  • Process for the production of 3-phenylisoserine
    Patent number: 7034178
    Abstract: This invention is drawn to a process for the production of (R,R)-phenylisoserine or a 1–4C-alkyl ester thereof.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: April 25, 2006
    Assignee: Altana Pharma AG
    Inventors: Wijnand Faber, Jan Koek, Jörg Senn-Bilfinger, Ton Vries
  • Process for the production of optically active 3-phenylisoserine
    Publication number: 20060041163
    Abstract: The invention relates to a process for preparation of (R, R)-3-phenylisoserine and its derivates.
    Type: Application
    Filed: October 14, 2005
    Publication date: February 23, 2006
    Inventors: Wijnand Faber, Jan Koek, Jorg Senn-Bilfinger, Ton Vries
  • Silyl ethers
    Publication number: 20060041134
    Abstract: Compounds of the formula 1, in which the substituents have the meanings mentioned in the description are valuable intermediates for preparing active compounds for the prevention and treatment of gastro-intestinal diseases.
    Type: Application
    Filed: December 18, 2003
    Publication date: February 23, 2006
    Applicant: Altana Pharma AG
    Inventors: Jan Koek, Bernhard Kohl, Jorg Senn-Bilfinger, Ton Vries
  • Chiral salt resolution
    Publication number: 20040229923
    Abstract: A method for resolving enantiomers of a compound containing the structure of the formula: 1
    Type: Application
    Filed: June 16, 2004
    Publication date: November 18, 2004
    Inventors: Glenn E. Wilcox, Mark E. Flanagan, Michael J. Munchhof, Ton Vries, Christian Koecher
  • Process for the production of 3-phenylisoserine
    Publication number: 20040176460
    Abstract: The invention relates to a process for the preparation of (R, R)-3-phenylisoserine and its derivatives.
    Type: Application
    Filed: December 31, 2003
    Publication date: September 9, 2004
    Inventors: Wijnand Faber, Jan Koek, Jorg Senn-Bilfinger, Ton Vries
  • Chiral salt resolution
    Publication number: 20030073719
    Abstract: A method for resolving enantiomers of a compound containing the structure of the formula: 1
    Type: Application
    Filed: May 23, 2002
    Publication date: April 17, 2003
    Inventors: Glenn E. Wilcox, Mark E. Flanagan, Michael J. Munchhof, Ton Vries, Christian Koecher
  • Method for making hydroxy-25-ene-vitamin D compounds
    Publication number: 20030009042
    Abstract: The present invention provides a method for preparing a novel class of vitamin D compounds in which the C-25 or equivalent position has a double bond. In addition, the side chain is optionally extended by one or two methylene or methyne groups. The compounds prepared by the method of the present invention are of value as prodrugs for active 1&agr;, 24-dihydroxylated vitamin D compounds.
    Type: Application
    Filed: August 26, 2002
    Publication date: January 9, 2003
    Applicant: Bone Care International, Inc.
    Inventors: Hans Wynberg, Ton Vries, Kees Pouwer
  • Method for making hydroxy-25-ene-vitamin D compounds
    Patent number: 6441207
    Abstract: The present invention provides a method for preparing a novel class of vitamin D compounds in which the C-25 or equivalent position has a double bond. In addition, the side chain is optionally extended by one or two methylene or methyne groups. The compounds prepared by the method of the present invention are of value as prodrugs for active 1&agr;, 24-dihydroxylated vitamin D compounds.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: August 27, 2002
    Assignee: Bone Care International, Inc.
    Inventors: Hans Wynberg, Ton Vries, Kees Pouwer