Abstract: Provided are antibodies that specifically bind to T-cell immunoglobulin domain and mucin domain 3 (Tim-3). The anti-Tim-3 antibodies can be used to treat, prevent or diagnose immune, cancerous, infectious diseases or other pathological disorders that may be modulated by Tim-3-mediated functions.

Abstract: A voice coil motor held immobile by magnetic attraction when not in use for photography purposes includes a base, a magnet fixed thereto, a carrier, a magnetic member, and a coil. The magnetic member is fixed to the carrier and is attracted by a permanent magnetic field (first MF) of the magnet on the base. The coil is fixed to the carrier and the magnetic member. When the voice coil motor is powered on, the coil generates a second magnetic field (second MF) opposing the first MF. The second MF reduces or eliminates the attractive force of the first MF of the magnet, to separate the carrier and its fittings and allow them to work freely. A lens module and an electronic device are further provided.

Abstract: Provided is a GII.4 norovirus virus-like particle or active fragment thereof, and use thereof, the virus-like particle comprising or being composed of an amino acid sequence shown as SEQ ID NO: 4. Further, provided is a composition or a kit comprising the GII.4 norovirus virus-like particle, and use thereof. The objective of covering multiple genotypes is achieved by using a single antigen of the invention, the process difficulty of the preparation for a pharmaceutical composition or a vaccine can be reduced, and the production cost is decreased. Also, provided is a norovirus immune composition or a kit comprising GII.2, GII.4, GII.6, and GII.17 norovirus virus-like particles or active fragments thereof, and use thereof.

Abstract: A decoder includes circuitry which, in operation, parses a first flag indicating whether a CCALF (cross component adaptive loop filtering) process is enabled for a first block located adjacent to a left side of a current block; parses a second flag indicating whether the CCALF process is enabled for a second block located adjacent to an upper side of the current block; determines a first index associated with a color component of the current block; and derives a second index indicating a context model, using the first flag, the second flag, and the first index. The circuitry, in operation, performs entropy decoding of a third flag indicating whether the CCALF process is enabled for the current block, using the context model indicated by the second index; and performs the CCALF process on the current block in response to the third flag indicating the CCALF process is enabled for the current block.

Abstract: A transparent light source system for a display device comprises a light source, and a light guide plate which includes an incident surface opposite to the light source, an upper surface, a lower surface parallel to the upper surface, and a lateral surface opposite to the incident surface. An outer light guide film is disposed outside the upper surface, first optical micro-structures allowing light transmitted in the light guide plate to be emitted from the upper surface are disposed on the upper surface, second optical micro-structures opposite to the first optical micro-structures are disposed on an inner surface of the outer light guide film, and the second optical micro-structures allow light emitted out of the first optical micro-structures to be emitted from an outer surface of the outer light guide film.

Abstract: In one embodiment, an ultrasound imaging system is configured to receive a set of ultrasound images of a target anatomical region. The set of ultrasound images is combined to create a composite tissue frame. The ultrasound imaging system determines whether an interventional instrument is present within the ultrasound images based on a set of trained classification algorithms based on the set of ultrasound images and the composite tissue frame. If an interventional instrument is detected, the ultrasound imaging system further determines whether an additional ultrasound frame should be captured to image the interventional instrument, and the steer angle to be used for the additional ultrasound image. The ultrasound imaging system determines a linear structure corresponding to the interventional instrument, and creates a blended image showing the interventional instrument and the composite tissue frame.

Abstract: The use of a mitoxantrone hydrochloride liposome and cyclophosphamide, vincristine and prednisone in the preparation of a drug for treating peripheral T-cell lymphoma (PTCL). The PTCL is preferably treatment-naïve PTCL. Other first-line and second-line drugs for treating PTCL may also be further used on the basis of the foregoing. A method for treating PTCL, the method comprising administering, to a patient, a therapeutically effective amount of a mitoxantrone hydrochloride liposome and cyclophosphamide, vincristine and prednisone. The combined administration of the drugs is safe and tolerable, has a small toxicity and few side effects, and can obtain a higher total objective remission rate (ORR) in treatment-naïve PTCL patients.

Abstract: A vibration isolation/damping satellite mount of a chopped carbon fiber reinforced thermoplastic composite material mainly includes two parts, and the two parts are connected through bolts. Considering the limitation of the molding process, the mount configuration is further optimized, and the mount structure is prepared by using the injection molding process. Furthermore, the vibration isolation/damping satellite mount of the chopped carbon fiber reinforced thermoplastic composite material prepared in the present invention can be used for large loads and complex working conditions, and the connectivity, overall strength stability, vibration isolation performance and service life of the mount all meet the design requirements.

Abstract: A portable blowing device configured for being worn around a neck of a human body, includes two arms each defining an airflow channel therein; and fans received in the arms respectively. The arm includes an inner side wall close to the neck and an outer side wall connected to the inner side wall. The arm includes an air inlet and an air outlet in communication with the airflow channel respectively. The air inlet is arranged at the inner side wall and/or the outer side wall. The fan is configured to generate an airflow passing through the air inlet, the airflow channel and the air outlet in sequence.

Abstract: The present invention belongs to the technical field of 3D reconstruction in the field of computer vision, and provides a dataset generation method for self-supervised learning scene point cloud completion based on panoramas. Pairs of incomplete point cloud and target point cloud with RGB information and normal information can be generated by taking RGB panoramas, depth panoramas and normal panoramas in the same view as input for constructing a self-supervised learning dataset for training of the scene point cloud completion network. The key points of the present invention are occlusion prediction and equirectangular projection based on view conversion, and processing of the stripe problem and point-to-point occlusion problem during conversion. The method of the present invention includes simplification of the collection mode of the point cloud data in a real scene; occlusion prediction idea of view conversion; and design of view selection strategy.

Abstract: An anti-peeping backlight module is formed by stacking an upper backlight module, a lower backlight module and a reflecting film disposed below the lower backlight module, wherein the upper backlight module is a transparent module, the lower backlight module is a transparent module or a non-transparent module, the upper backlight module is a collimating backlight module or a diffusion backlight module, the lower backlight module is a collimating backlight module or a diffusion backlight module, and the upper backlight module and the lower backlight module have different properties. The anti-peeping backlight module realizes beam splitting and collimation and can be used as various backlight modules, the beam splitting angle is adjustable, the efficiency is high, and can be controlled independently.

Abstract: The disclosure is directed to systems and techniques for executing a documentation application displaying a graphical user interface having a content-creation field configured to receive textual input. A link-creation window may be generated, which facilitates browsing third-party content without leaving a current application. Using the disclosed interface, a user can generate a selectable graphical object that links to third-party content from within the context of the content-creation field interface.

Abstract: A drag knife apparatus for cutting stencil patterns in sheet material comprises a drag knife holder biased downwardly into cutting position by a variable tension spring and lifted out of cutting position by a relay-controlled solenoid. The knife holder is counterweighted through a lever arm. The apparatus can be used to form a sandblasting stencil from material adhesively held in position on the face of a monument during the stencil cutting process. The stencil is removed after the sandblasting step.

Abstract: A chemical mechanical polishing composition comprises, consists of, or consists essentially of a liquid carrier, abrasive particles in the liquid carrier, a pyrophosphate compound, and a sulfonate compound or a compound including a quaternary ammonium group.

Abstract: System analysis by receiving a model of a complex system design. The model includes at least one layer. The analysis includes performing a plurality of simulations of the performance of the layer. The number of simulations is determined according to a number of system components associated with the layer. The analysis further includes determining a worst-case result for a set of simulations from the plurality of simulations and assigning the worst-case result to an overall system simulation.

Abstract: A laser engraving machine with a three-point suspension system and an inverted X-Y axis support system wherein the X-axis beam is to and mounted below the Y-axis beams and the Y-axis beams are mounted inwardly of the outer ends of the X-axis beam and are structurally integrated with the machine housing. In addition, a counterweight in the form of a second, independently activatable laser is added to the drive belt to reduce or eliminate vibration during rapid reciprocal movement of the tool during an engraving process.

Abstract: A wearable air conditioner includes a shell for being worn around a wearing portion of a user, a fan and a temperature regulating member disposed in the shell. The shell includes a first air passage, a first accommodating chamber, at least one air outlet in communication with the first air passage, and vent holes in communication with the first accommodating chamber. The temperature regulating member is configured for generating heat energy or cold energy. The temperature regulating member is in thermal connection with a sidewall of the first accommodating chamber. An airflow generated by the fan is capable of entering the first air passage and then exiting the shell via the at least air outlet.

Abstract: The present disclosure belongs to the technical field of sewage treatment, and discloses a method and system for enhanced culture of aerobic granular sludge. The system includes a reaction tank, a water inlet and outlet unit, an aeration unit, and a sludge discharge unit. The water inlet and outlet unit includes a water inlet pump, a water inlet electric valve, a liquid flowmeter, a sewage uniform distribution treatment device, buffers, a water drainage pipe, and a water drainage electric valve. The aeration unit includes a blower, microporous aerators, and a gas flowmeter. The sludge discharge unit includes sludge discharge pumps, a sludge discharge pipe, a sludge discharge electric valve, and a sludge concentration meter. In the present disclosure, a multi-point uniform water distribution method is used.

Abstract: Exemplary embodiments relate to a protein engineering pipeline configured to optimize or improve proteins for specified functions. The problem space of such a task can grow quickly based on the sequence of the protein being optimized and the functions for which the protein is being designed. The solutions described herein allow the problem space to be efficiently searched by applying a combination of a protein design pipeline and an evaluation procedure performed on a quantum computer. As a result, single or multiple amino acid substitutions at a site of interest may be predicted in order to generate optimized protein variants.

Abstract: A morphing part to be morphed and a morphing effect are acquired. Human body contour point information is acquired by detecting a human contour point of a human sideway image. A morphing region is determined according to the human contour point information and the morphing part. The morphing region is an image region to be morphed in the human sideway image. A human orientation is determined according to the human contour point information. A morphing direction of the morphing region is determined according to the human orientation and the morphing effect. Morphing is performed along the morphing direction in the morphing region.