Abstract: The present disclosure provides an ?-olefin extractant and a method for separating an alkane and an ?-olefin, wherein the ?-olefin extractant comprises an alcohol-amine, a saturated monoketone having a carbon chain length of 7-10 and a monovalent salt of a Group IB metal, wherein the alcohol-amine, the saturated monoketone having a carbon chain length of 7-10 and the monovalent salt of a Group IB metal are in a mass ratio of (0.9-2.0):(0.8-1.5):(0.1-0.6). In the present disclosure, the technical principle of complexing extractive rectification is utilized and achieves the purpose of separating an olefin from an alkane by adding a complexing extractant to form a relatively stable complex between a metals and the olefin. The present disclosure has advantages of good separation effect and high product yield.

Abstract: Provided are antibodies that specifically bind to TIGIT (T cell immunoreceptor with Ig and ITIM domains, WUCAM or Vstm3) and inhibit Tigit-mediated cellular signaling and activities in immune cells. The anti-TIGIT antibodies can be used to treat or diagnose cancer, infectious diseases or other pathological disorders that may be modulated by Tigit-mediated functions.

Abstract: The present invention belongs to the field of bioengineering technologies, and in particular, to a production method of recombinant Escherichia coli (E. coli) and high-purity ursodeoxycholic acid (UDCA). The present invention constructs novel double-enzyme co-expression gene engineered bacteria, that is, recombinant E. coli. The bacteria simultaneously expresses 7?-hydroxysteroid dehydrogenase (7?-HSDH) and glucose dehydrogenase (GDH). The bacteria is applicable to the production of high-purity UDCA. The yield of a target product is increased through the joint expression and application of 7?-HSDH and GDH. The production method of high-purity UDCA in the present invention is simple, generates a small amount of impurities in a production process, is a green process that satisfies environmental protection requirements, and has significant industrial application value.