Abstract: An array substrate includes a base substrate, including a display area and a peripheral area; a driving circuit layer, located at one side of the base substrate and including a plurality of data lines and a plurality of scanning lines, where the plurality of data lines extend along a first direction and are arranged at intervals along a second direction, the plurality of scanning lines extend along the second direction and are arranged at intervals along the first direction, and the data line and the scanning line intersect with each other to define a plurality of sub-pixel areas; and a metal layer, located at one side of the driving circuit layer away from the base substrate, where the metal layer includes a plurality of metal blocks arranged at intervals, and the metal block is located at an intersection of the data line and the scanning line.

Abstract: Disclosed are an anti-DLL3 antibody and a preparation method therefor, a drug conjugate and application thereof. The anti-DLL3 antibody in the present invention has good internalization activity, has better binding activity with human DLL3 protein, and has strong affinity at the protein level. The antibody conjugated drug targeting DLL3 in the present invention has good druggability, biological activity, and anti-tumor activity in vitro and vivo, and can achieve an application of cytotoxic drugs in treating tumor patients comprising SCLC and having neuroendocrine characteristics.

Abstract: A joint imaging system based on unmanned aerial vehicle platform and an image enhancement fusion method are provided. The system includes a flying unit as a load platform, a shutter control system for controlling the operation of a load camera, a posture control system for recording the movement track and POS data of the flying unit, an airborne image transmission system for communicating with ground equipment, and an onboard computing unit with an image processing module for receiving the output images and performing image processing and fusion.

Abstract: The provided are sealing components, a focused ultrasound treatment system and an operation method thereof, and a semi-dry acoustic coupling apparatus. The focused ultrasound treatment system includes a medium container with two ends opened, a waterproof adhesive ring, an ultrasound emission device, a gas pressure increase/decrease component, a coupling fluid increase/decrease component, and a pressure control module, where a first connecting surface of the waterproof adhesive ring is configured to attach to the skin of a patient; a second connecting surface of the waterproof adhesive ring is bonded with a first end of the medium container, and a second end of the medium container is tightly connected with a shell of the ultrasound emission device. The provided has advantages of simple device, reduced attenuation, thorough coupling, improved efficacy, reduced risk, and no damage to an ultrasonic imaging probe.

Abstract: Provided in the embodiments are a transfer structure and a method thereof, and a transfer device and a manufacturing method thereof. The transfer structure includes: a first electrode, a piezoelectric layer, a second electrode and an adhesive layer stacked on a substrate in sequence, wherein the first electrode and the second electrode are insulated from each other. The transfer structure further includes: a position-limiting layer, wherein the position-limiting layer includes a cavity; the piezoelectric layer and at least part of the adhesive layer are located in the cavity of the position-limiting layer; and in the direction perpendicular to the substrate, the distance between the surface, away from the substrate, of the position-limiting layer and the substrate is greater than the distance between the surface, away from the substrate, of the adhesive layer and the substrate.

Abstract: A TROP2 targeting antibody-drug conjugate, and a preparation method and use therefor. The antibody-drug conjugate is shown in formula I. Said type of compound has a good targeting property, a good inhibitory effect on tumor cells positively expressing TROP2, and good druggability and high safety. The present antibody drug conjugate has an inhibitory effect on TROP2, and also a good inhibitory effect on at least one of NCI-N87, MDA-MB-468 and BXPC3 cells.

Abstract: An electronic device displays an application window in a floating window state, where the application window includes a first control. Following a first sliding operation starting from the first control, the electronic device may move the application window along a sliding track of the first sliding operation, where the first sliding operation is a first movement in a first direction. The electronic device may display the application window in a full-screen state in response to a first lifting operation after the first movement, where before displaying the application window in the full-screen state, the electronic device further continues to move the application window in the first direction in response to the first lifting operation after the first movement, where a window size of the application window gradually increases in a moving process until the application window is in the full-screen state.

Abstract: A shift-register unit, a grid driving circuit and a displaying device, which relates to the technical field of displaying. In the present disclosure, the oxide-semiconductor layers of the oxide thin-film transistors may be delimited into regions according to the total channel widths and the channel lengths required by the oxide thin-film transistors in the shift-register unit, wherein the sum of the widths of the independent semiconductor branches obtained by the delimitation is equal to the required total channel width. Accordingly, one oxide thin-film transistor can realize the required total channel width by using the one or more semiconductor branches, to ensure the normal operation of the oxide thin-film transistor, whereby the oxide-semiconductor layers of the different oxide thin-film transistors can be configured differently, to realize the purpose of reducing the border frame of the displaying device.

Abstract: A controller (600) for a radiotherapy device (320) is provided; the radiotherapy device (320) being configured to provide therapeutic radiation to a patient (308) via a source (300) of therapeutic radiation, wherein the radiotherapy device (320) comprises a first rotatable member (304), the rotation of which can alter a physical attribute of the therapeutic radiation provided, and a patient support member (310), which is linearly moveable in at least one of a longitudinal direction and a lateral direction. The controller (600) comprises a first rotatable actuator (608) for controlling a movement of the first rotatable member (304) and a second actuator (620) for controlling a movement of the patient support member (310).

Abstract: An antibody-drug conjugate, and an intermediate thereof, a preparation method therefor, and an application thereof. Provided is an antibody-drug conjugate as represented by formula I. The compound has good targetability, has a good inhibitory effect on HER3-positive tumor cells, and has good druggability and high safety. The antibody-drug conjugate has an inhibitory effect on HER3, has an inhibitory effect on SK-BR-3 and SW620 cells, and also has a good inhibitory effect on at least one of 22Rv1, LNCaP, NCI-H820, OVCAR-8, and HCC827 cells.

Abstract: Disclosed is a joint imaging system based on unmanned aerial vehicle platform and an image enhancement fusion method, which are used for realizing thermal infrared oblique photogrammetry and real-time fusion of thermal infrared images and visible light images. The system includes a flying unit as a load platform, a shutter control system for controlling the operation of a load camera, a posture control system for recording the movement track and POS data of the flying unit, an airborne image transmission system for communicating with ground equipment, and an onboard computing unit with an image processing module for receiving the output images and performing image processing and fusion, so as to quickly collect thermal infrared images and visible light images, and improve the recognition capability of feature points in the process of thermal infrared oblique photogrammetry, and ensure the success rate and accuracy of building the three-dimensional temperature field model.

Abstract: A shift-register unit, a grid driving circuit and a displaying device, which relates to the technical field of displaying. In the present disclosure, the oxide-semiconductor layers of the oxide thin-film transistors may be delimited into regions according to the total channel widths and the channel lengths required by the oxide thin-film transistors in the shift-register unit, wherein the sum of the widths of the independent semiconductor branches obtained by the delimitation is equal to the required total channel width. Accordingly, one oxide thin-film transistor can realize the required total channel width by using the one or more semiconductor branches, to ensure the normal operation of the oxide thin-film transistor, whereby the oxide-semiconductor layers of the different oxide thin-film transistors can be configured differently, to realize the purpose of reducing the border frame of the displaying device.

Abstract: A B7-H3 targeting antibody-drug conjugate, and a preparation method therefor and use thereof. Provided is the antibody-drug conjugate as shown in formula I. The compound has a good targeting property, good inhibitory effect on tumor cells positively expressing B7-H3, and good druggability and safety. The present antibody-drug conjugate has an inhibitory effect against B7-H3, and also a good inhibitory effect against at least one of NCI-N87, A375, LN-229, PA-1, MDA-MB-468, Calu-6 and HS-700T cells.

Abstract: The embodiment of the present disclosure provides a display substrate including a plurality of gate lines and a plurality of data lines. The plurality of gate lines each extend along a first direction, and the plurality of data lines each extend along a second direction. The plurality of data lines are spatially crossed with the plurality of gate lines to define a plurality of pixel regions, and at least one sub-pixel is provided in each of the plurality of pixel regions. At least three sub-pixels adjacent to each other along the second direction form one of a plurality of pixels. All the sub-pixels within one of the plurality of pixels are coupled to a same data line of the plurality of data lines.

Abstract: An array substrate includes a base substrate, including a display area and a peripheral area; a driving circuit layer, located at one side of the base substrate and including a plurality of data lines and a plurality of scanning lines, where the plurality of data lines extend along a first direction and are arranged at intervals along a second direction, the plurality of scanning lines extend along the second direction and are arranged at intervals along the first direction, and the data line and the scanning line intersect with each other to define a plurality of sub-pixel areas; and a metal layer, located at one side of the driving circuit layer away from the base substrate, where the metal layer includes a plurality of metal blocks arranged at intervals, and the metal block is located at an intersection of the data line and the scanning line.

Abstract: A shift-register unit, a grid driving circuit and a displaying device, which relates to the technical field of displaying. In the present disclosure, the oxide-semiconductor layers of the oxide thin-film transistors may be delimited into regions according to the total channel widths and the channel lengths required by the oxide thin-film transistors in the shift-register unit, wherein the sum of the widths of the independent semiconductor branches obtained by the delimitation is equal to the required total channel width. Accordingly, one oxide thin-film transistor can realize the required total channel width by using the one or more semiconductor branches, to ensure the normal operation of the oxide thin-film transistor, whereby the oxide-semiconductor layers of the different oxide thin-film transistors can be configured differently, to realize the purpose of reducing the border frame of the displaying device.

Abstract: A method for interaction between devices based on a pointing operation and an electronic device. The electronic device may be a mobile phone or the like. In the method, a pointing operation performed by a user from a handheld device to a target device is detected via an acceleration sensor, a gyroscope, an IMU, a camera, or the like of the handheld device, and a wireless positioning function of the handheld device is triggered. When it is identified that an axis of the handheld device intersects or approximately intersects with the target device, at least one type of feedback such as visual feedback, sound feedback, and vibration may be provided on the handheld device and/or the target device, login account information and device information of the target device are transmitted to the handheld device, and a target device control window is displayed on the handheld device.

Abstract: A B7-H3 targeting antibody-drug conjugate, and a preparation method therefor and use thereof. Provided is the antibody-drug conjugate as shown in formula I. The compound has a good targeting property, good inhibitory effect on tumor cells positively expressing B7-H3, and good druggability and safety. The present antibody-drug conjugate has an inhibitory effect against B7-H3, and also a good inhibitory effect against at least one of NCI-N87, A375, LN-229, PA-1, MDA-MB-468, Calu-6 and HS-700T cells.

Abstract: A TROP2 targeting antibody-drug conjugate, and a preparation method and use therefor. The antibody-drug conjugate is shown in formula I. Said type of compound has a good targeting property, a good inhibitory effect on tumor cells positively expressing TROP2, and good druggability and high safety. The present antibody drug conjugate has an inhibitory effect on TROP2, and also a good inhibitory effect on at least one of NCI-N87, MDA-MB-468 and BXPC3 cells.

Abstract: The present disclosure provides a method for performing a non-revisiting coverage task by a manipulator with a least number of lift-offs, and relates to the technical field of manipulator path planning. By explicitly considering lift-offs of an end-effector from a surface of an object due to kinematic constraints when the manipulator performs a task of covering the surface of the object, this method transforms a problem of coverage path design into a problem of sub-cell decomposition and solves the problem to obtain an approach for the manipulator to cover a sub-cell. The method of the present disclosure minimizes the number of lift-offs of the end-effector from the surface of the object when the manipulator performs the coverage task.