Abstract: A heterogeneous dynamic random access memory (DRAM) module, including: a first set of DRAM chips; a second set of DRAM chips, wherein the DRAM chips in the second set of DRAM chips have a lower storage reliability than the DRAM chips in the first set of DRAM chips; and a controller coupled to the first and second sets of DRAM chips, wherein the controller includes a DRAM access engine for accessing the second set of DRAM chips and for ensuring a data storage integrity of the second set of DRAM chips.

Abstract: An enhanced FTL system and method are provided for eliminating redundant write operations. A method is disclosed, including: processing a data write operation from a host that deploys a journaling scheme, wherein the data write operation includes a specified LBA that maps to a PBA in a SSD memory; calculating a signature of a data block during a write operation; detecting whether the data write should be handled as journal or non-journal write operation without assistance from the host; in response to a detected journal write operation, allocating a new PBA, writing the data block to the new PBA, updating a mapping table with a new LBA-PBA mapping, and inserting the signature into a signature table for the new LBA-PBA mapping; and in response to a detected non-journal write operation, mapping the specified LBA to an existing PBA if the signature matches a stored signature in the mapping table.

Abstract: Methods for enhancing the speed performance of solid-state storage devices using stream-aware garbage collection. A garbage collection method in according to an embodiment includes: searching, in each of a plurality of super-block groups G, for a super-block set C that satisfies: all of the super-blocks m within the super-block set C in the super-block group G contain a lesser amount of valid data than the other super-blocks within the super-block group G; and a total amount of valid data within the super-block set C are just enough to complete an entire super-block; selecting the super-block group G that includes the super-block set C with the maximum number of super-blocks m; and performing garbage collection on the super-block set C in the selected super-block group G.

Abstract: The invention provides antibody heavy chain constant regions with a hinge region modified to reduce binding to Fc? receptors. The modification occurs within positions 233-236 by replacement of natural residues by glycine(s) and/or deletion(s). Such modifications can reduce binding of an antibody bearing such a constant region to Fc? receptors to background levels. The constant regions can be incorporated into any format of antibody or Fc fusion protein. Such antibodies or fusion proteins can be used in methods of treatment, particularly those in which the mechanisms of action of the antibody or Fc fusion protein is not primarily or at all dependent on effector functions, as is the case when an antibody inhibits a receptor-ligand interaction or agonizes a receptor.

Abstract: Disclosed herein are methods for a multiple degree-of-freedom (DOF) motor system with reduced number of electromagnet control phases. The motor system includes a first body that is able to move relative to a second body along multiple DOFs. The first body has at least one magnetic positioner attached. The second body has a plurality of controlled electromagnets. Control signals, the total number of phases of which is less than half the total number of electromagnets, energize at least one of the controlled electromagnets to create magnetic interaction with at least one magnetic positioner on the first body, and to control the movement of the first body relative to the second body along designated dimension(s).

Abstract: An aerial system includes a body, a lift mechanism coupled to the body, a processing system, and at least one camera. The aerial system also includes a first motor configured to rotate the at least one camera about a first axis and a second motor configured to rotate the at least one camera about a second axis. The processing system is configured to determine a direction of travel of the aerial system and to cause the first motor and the second motor to automatically orient the at least one camera about the first axis and the second axis such that the at least one camera automatically faces the direction of travel of the aerial system.

Abstract: A translation model based training method is provided for a computer device. The method includes inputting a source sentence to a translation model, to obtain a target sentence outputted by the translation model; determining a fidelity of the target sentence to the source sentence; using the target sentence and a reference sentence as input of a discriminator model, using the fidelity as output of the discriminator model, and training the discriminator model on a performance of calculating a similarity between the target sentence and the reference sentence; outputting the similarity by using the discriminator model; and using the source sentence as input of the translation model, using the target sentence as output of the translation model, and using the similarity as a weight coefficient, and training the translation model on a performance of outputting the corresponding target sentence according to the input source sentence.

Abstract: An aerial system and method of operating an aerial system is provided. The aerial system includes a body, a lift mechanism, a processing system, a camera, and a sensor module. The lift mechanism is coupled to the body and configured to controllably provide lift and/or thrust. The processing system is configured to control the lift mechanism to provide flight to the aerial system. The camera is coupled to the body and is configured to obtain images of an environment proximate the aerial system. The sensor module is coupled to the body and includes an emitter and a receiver. The receiver is configured to sense data related to an ambient environment associated with the aerial system. The processing system controls a controllable parameter of the lift mechanism or the emitter as a function of the sensed data.

Abstract: A method for controlling an aerial system with a rotor enclosed by a housing, including: operating the rotor in a flight mode, detecting a grab event indicative of the aerial system being grabbed, and automatically operating the rotor in a standby mode. A method for controlling an aerial system including a central axis extending normal to a lateral plane of the aerial system, including: generating a first aerodynamic force with a set of rotors enclosed by a housing, detecting that an acute angle between the central axis and a gravity vector is greater than a threshold angle, and operating each rotor of the set of rotors to cooperatively generate a second aerodynamic force less than the first aerodynamic force with the set of rotors.

Abstract: Disclosed herein is a pharmaceutical combination for use in the prevention, delay of progression or treatment of cancer, wherein the pharmaceutical combination exhibits a synergistic efficacy. The pharmaceutical combination comprises a humanized antagonist monoclonal antibody against PD- and a RAF inhibitor. Also disclosed herein is a combination for use in the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject a therapeutically effective amount of a humanized antagonist monoclonal antibody against PD-1 and a therapeutically effective amount of a RAF inhibitor.

Abstract: A system, method and program product for exploiting in-storage transparent compression. A storage infrastructure is disclosed that includes: a storage device having physical block address (PBA) storage of a defined capacity, a transparent compression system that compresses data written to the PBA storage, and a logical block address-to-physical block address mapping table; and a host having a memory management system that includes: an initialization system that allocates an amount of logical block address (LBA) storage for the host having a capacity greater than the defined capacity of the PBA storage, and that creates a dummy file that consumes LBA storage without consuming any PBA storage; a system that gathers current PBA and LBA usage information.

Abstract: The invention provides antibody heavy chain constant regions with a hinge region modified to reduce binding to Fc? receptors. The modification occurs within positions 233-236 by replacement of natural residues by glycine(s) and/or deletion(s). Such modifications can reduce binding of an antibody bearing such a constant region to Fc? receptors to background levels. The constant regions can be incorporated into any format of antibody or Fc fusion protein. Such antibodies or fusion proteins can be used in methods of treatment, particularly those in which the mechanisms of action of the antibody or Fc fusion protein is not primarily or at all dependent on effector functions, as is the case when an antibody inhibits a receptor-ligand interaction or agonizes a receptor.

Abstract: The present invention provides a sound generator. A magnetic circuit system of the sound generator forms a mortise-and-tenon structure between a magnet and a lower plate, and the magnet and a pole plate, through tenons and mortises, which enlarges the mutual contact areas, and is more convenient for processing positioning, preventing assembling dislocation, enlarging the gluing area and improving the drop reliability and therefore improving the structural stability of the magnetic circuit system.

Abstract: The present disclosure provides a speaker, comprising a basin frame with a receiving space, a vibration system disposed at the basin frame, and a magnetic circuit system configured for driving the vibration system to generate sounds by vibration, the vibration system comprises a diaphragm with an outer edge fixedly held by the basin frame and a voice coil configured for driving the diaphragm to vibrate, the voice coil includes a first voice and a second voice coil fixedly connected to the first voice coil, the first and second voice coils are disposed in parallel and symmetrically, the first and second voice coils are integrally wound molded and the winding direction of the first voice coil is opposite to that of the second voice coil. The speaker provided by the present disclosure could improve utilization of magnetic field, provide better vibration effect and reduce resonance frequency.

Abstract: The present invention provides a sound generator, including a magnetic circuit system having a magnet and a lower plate for carrying the magnet. The magnet includes a first surface opposite to the lower plate and a second surface opposite to the first surface. The first surface of the magnet protrudes to form a first bolt, the lower plate is provided with a lower plate jack matching with the first bolt, and the first bolt is inserted into the lower plate jack. The sound generator of the present disclosure improves the structural stability of the magnetic circuit system and is convenient for positioning.

Abstract: A method according to embodiments includes: storing an entire hash table of a table R in memory of a computational storage device; storing a second table S in storage media of the computational storage device, the table R being smaller than the table S, wherein the hash JOIN operation is directed to combining a cs-th column in the table S and a cr-th column in the table R; wherein, for each row of the table S, the computational storage device configured to perform a method, including: applying a hash function to a value of the cs-th column to provide a hash result; looking up the hash result in the hash table stored in the memory of the computational storage device; and if the hash result is found, sending the row of the table S and a corresponding row index of the table R to the host computing system.

Abstract: The present disclosure relates to the field of energy storage, and provides a rapid-response energy storage system and a using method thereof.

Abstract: The present disclosure relates to the field of energy storage, and provides a regenerative compressed air energy storage system and a using method thereof. The system comprises a compressor unit, a high-temperature heat exchanger, a medium-temperature heat exchanger, an air storage chamber, a regulating valve, a medium-temperature regenerator, a high-temperature regenerator and an expander unit which are connected in sequence. The low-temperature side of the high-temperature heat exchanger, a high-temperature heat reservoir, a first valve, the high-temperature side of the high-temperature regenerator, a high-temperature cold reservoir and a second valve are connected in sequence. The low-temperature side of the medium-temperature heat exchanger, a medium-temperature heat reservoir, a third valve, the high-temperature side of the medium-temperature regenerator, a medium-temperature cold reservoir and a fourth valve are connected in sequence.

Abstract: Disclosed herein is a method for the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject in need thereof a PARP inhibitor, particularly, (R)-2-fluoro-10a-methyl-7,8,9,10,10a,11-hexahydro-5,6,7a,11-tetraazacyclohepta[def]cyclopenta[a]fluoren-4(5H)-one, a sesqui-hydrate thereof, or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor or a chemotherapeutic agent. Also, disclosed a pharmaceutical combination comprising a PARP inhibitor, particularly, (R)-2-fluoro-10a-methyl-7,8,9,10,10a,11-hexahydro-5,6,7a,11-tetraazacyclohepta[def]cyclopenta[a]fluoren-4(5H)-one, a sesqui-hydrate thereof, or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor, or a chemotherapeutic agent and the use thereof.

Abstract: Provided are antibodies that specifically bind to Programmed Death-1 (PD1, Pdcd-1, or CD279) ligand (PD-L1) and inhibit PD-L1-mediated cellular signaling and activities in immune cells, antibodies binding to a set of amino acid residues required for its ligand binding, and uses of these antibodies to treat or diagnose cancer, infectious diseases or other pathological disorders modulated by PD-L1-mediated functions.