Patents by Inventor Tong Zhu
Tong Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230096410Abstract: The present disclosure provides an innate immunity cell such as a gamma delta T (gdT) cell, Natural Killer (NK) cell, or macrophage having 2-[3-(1,3-dicarboxypropyl)ureido] pentanedioic acid (DUPA) chemically conjugated to the cell surface. The DUPA-conjugated cells provided herein demonstrate increased cytotoxicity toward cancer cells expressing PSMA. DUPA-conjugated cells can be primary cells or cells of a cell line. Also provided are methods of conjugating DUPA to the surface of NK cells, gamma delta T (gdT) cells, or macrophages and methods of treating cancer using DUPA-conjugated NK cells, gamma delta T (gdT) cells, or macrophages.Type: ApplicationFiled: March 5, 2021Publication date: March 30, 2023Applicant: Sorrento Therapeutics, Inc.Inventors: Yanwen Fu, Reyna Lim, Daniel Lee, Matthew Buschman, Tong Zhu, Alisher B. Khasanov
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Publication number: 20230073710Abstract: An intelligent test system for traffic load engineering detection of road construction comprises a support part; a sample box part used for containing samples and carrying out a load test in a vertical direction and a direct-shear test in a horizontal direction; a simulated road load applying part used for applying multiple simulated road loads to the samples; a vertical load applying part used for providing multiple loads in the vertical direction for the samples; a horizontal load applying part used for providing loads in the horizontal direction for the sample box part; an automatic sand-compaction part used for quantitatively compacting the samples layer by layer; a water-level fluctuation part used for simulating rising and falling of a tide level; a dry-wet cycle part used for simulating a rain and a sunlight; and an acquisition part used for acquiring data generated during the test.Type: ApplicationFiled: November 10, 2022Publication date: March 9, 2023Inventors: Shuai WANG, Tong Lu, Aixun Wang, Wenxiang Li, Yunjie Dong, Mingzhao Wang, Te Liu, Xianyong Kong, Jing Zhu
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Publication number: 20230050445Abstract: A bridge structure dynamic response of a bridge structure under the action of heavy duty vehicle load is obtained through sensors arranged on the bridge structure; according to vertical vibration acceleration ao and vertical deflection yo of the bridge at a center of gravity o of the heavy duty vehicle and speed of the heavy duty vehicle Uvehicle, a response of a table top of a vibration table is reconstructed, and interaction force of the vehicle-bridge coupling model is obtained; a nonlinear finite element model of the bridge structure is established, and the vehicle-bridge interaction force is taken as external force, and the dynamic response of the bridge structure is taken as a structural response, and modification of the finite element model of the bridge structure is completed through a nonlinear parameter identification method. The invention is mainly used for updating a bridge model.Type: ApplicationFiled: September 30, 2022Publication date: February 16, 2023Applicants: Harbin Institute of Technology, Zhong Dian Jian Ji Jiao Expresswayinvestment Development Co., Ltd., Harbin Institute of Technology (Beijing) Industrial Technology Innovation Research Institute Co.,LtdInventors: Yong DING, Zhiqiang ZHANG, Jian LIU, Tong ZHOU, Xianzhuo JIA, Ying CHANG, Bin ZHU, Guang CHEN, Cong ZENG
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Publication number: 20230033267Abstract: A method for video processing is provided. The method comprises obtaining an image of a scene, obtaining a video that records an area included in the scene, determining one or more frames from the plurality of frames of the video, determining pairs of matched features, generating a plurality of composite frames by combining each of the selected one or more frames with the image of the scene based on the pairs of matched features, and generating a composite video based on the plurality of composite frames. Each of the pairs of matched features is related to an object that is in both the image and the one or more frames. Each of the pairs of matched features is associated with one or more pixels of the image of the scene and one or more pixels of a selected frame of the one or more frames.Type: ApplicationFiled: June 16, 2022Publication date: February 2, 2023Inventors: Tong RAO, Yi ZHU, Chengfeng HUANG
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Patent number: 11551114Abstract: Embodiments of the present disclosure provide a method and apparatus for recommending a test question, and an intelligent device. The method includes: acquiring a plurality of skill entities of a post; calculating, according to the data of the post, a weight value of each of the plurality of skill entities; and acquiring, according to the weight value of each skill entity, a recommended test question of the post from a question bank.Type: GrantFiled: December 12, 2019Date of Patent: January 10, 2023Assignee: Baidu Online Network Technology (Beijing) Co., Ltd.Inventors: Chuan Qin, Hengshu Zhu, Chen Zhu, Chao Ma, Jingshuai Zhang, Peng Wang, Tong Xu
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Publication number: 20220409648Abstract: Among the various aspects of the present disclosure is the provision is the provision of a SARM1 activating agent or prodrug thereof and methods of using same.Type: ApplicationFiled: June 28, 2022Publication date: December 29, 2022Inventors: Jeffrey Milbrandt, Aaron DiAntonio, Tong Wu, Amy Strickland, Adam Bloom, Yo Sasaki, Jian Zhu, Yurie Yamada
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Patent number: 11527592Abstract: The present disclosure relates to terminals and display screens. In an embodiment, a terminal includes a display area, the display area includes at least two display regions, the at least two display regions include a first display region and a second display region, a pixel density of the first display region is less than a pixel density of the second display region, and the pixel density of the first display region is less than or equal to a maximum pixel density of the first display region in a transparent state when the first display region is unlit.Type: GrantFiled: May 18, 2018Date of Patent: December 13, 2022Assignee: YUNGU (GU'AN) TECHNOLOGY CO., LTD.Inventors: Qi Shan, Tong Xu, Xuejing Zhu
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Patent number: 11519890Abstract: Disclosed is a detection method for N-nitrosodimethylamine (NDMA) impurities, comprising: (1) obtaining a test solution containing a sample to be tested; and (2) detecting the test solution by means of gas chromatography-mass spectrometry to determine the content of an N-nitrosodimethylamine impurity in the sample. The method provided in the present invention has a good separating effect, a wide linear range, a high sensitivity and a good method durability, and can detect the content of N-nitrosodimethylamine (NDMA) in the sample rapidly and effectively.Type: GrantFiled: July 10, 2018Date of Patent: December 6, 2022Assignee: ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTDInventors: Tan Xiao, Tianpei Huang, Jinsheng Lin, Qiang Zhou, Tong Wu, Danfeng Ye, Hong Cai, Wenquan Zhu, Wenbin Chen, Min Li
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Patent number: 11519663Abstract: A refrigerator having a thawing device. The thawing device includes: a cavity, a device door, a radio frequency generator module, an upper electrode plate and a lower electrode plate, and a detection module, configured to detect an incident wave signal and a reflected wave signal of an electrical connection wire connecting the radio frequency generation module to the upper electrode plate, and calculate a load impedance of the radio frequency generation module according to a voltage and a current of the incident wave signal and a voltage and a current of the reflected wave signal to determine the thawing progress of the object to be processed.Type: GrantFiled: December 6, 2019Date of Patent: December 6, 2022Assignee: HAIER SMART HOME CO., LTD.Inventors: Tong Xu, Xiaobing Zhu, Peng Li, Ming Wang, Jianbin Dai
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Patent number: 11473829Abstract: A thawing method for a thawing device includes: generating, by a radio frequency generation module, a radio frequency signal in a frequency range of 40 to 42 MHz; obtaining the radio frequency signal; and generating, by an upper electrode plate and a lower electrode plate, radio frequency waves of corresponding frequency in a thawing chamber according to the radio frequency signal, and thawing an object to be processed in the thawing chamber. Radio frequency waves using the above frequency range have shorter thawing time, higher temperature-uniformity and lower juice loss rate than radio frequency waves of other frequencies.Type: GrantFiled: December 6, 2019Date of Patent: October 18, 2022Assignee: HAIER SMART HOME CO., LTD.Inventors: Kui Zhang, Xiaobing Zhu, Peng Li, Ming Wang, Jianbin Dai, Tong Xu
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Publication number: 20220290687Abstract: A portable blowing device includes a body and fans arranged in the body. Air channels are arranged in the body and extend in the length direction of the body to allow airflow to pass through. Wind shields are arranged in the air channels, and a periphery of the wind shield is closely connected with a side wall of the air channel so that a sub-air channel is formed between the wind shield and the side wall of the air channel. Air outlets are formed in the side wall for communicating with outside and the sub-air channel, and airflow generated by the fan can enter the sub-air channel and then exits the air outlets. Because of the reduced volume of the sub-air channel, the airflow is concentrated after entering the sub-air channel, and airflow exiting the air outlets is strengthened, so that the cooling effect and the user experience are improved.Type: ApplicationFiled: May 8, 2021Publication date: September 15, 2022Applicant: Shenzhen Lanhe Technologies Co., Ltd.Inventors: Kai LIU, Xunhuan WU, Guang YANG, Weiping LI, Jun ZHU, Quan LV, You LAI, Tong LI
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Patent number: 11442418Abstract: The present disclosure provides a fire test system and method for tunnel structure based on real-time fusion of numerical and physical spaces. The fire test system includes: a physical test unit, to perform a holographic fire test on the typical segment components of tunnel structure system in a physical space, to obtain holographic characteristic parameter data of the typical components; a numerical analysis unit, to establish a full-scale numerical model of the tunnel-stratum composite system in a numerical space, to obtain multi-field coupling boundary data of the typical components; and a fusion control unit, to control and adjust a multi-field coupling boundary of the physical space according to the multi-field coupling boundary data, and to update and adjust an input parameter of the numerical space according to the holographic characteristic parameter data.Type: GrantFiled: December 21, 2020Date of Patent: September 13, 2022Assignee: TONGJI UNIVERSITYInventors: Zhiguo Yan, Hehua Zhu, Tong Zhang, Wenqi Ding, Yi Shen
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Publication number: 20220252440Abstract: A calibration and verification system for a directional sensor, comprising an industrial control computer and a directional sensor, wherein the industrial control computer is connected to a sensor signal acquisition system, a first triaxial Helmholtz coil and a second triaxial Helmholtz coil, respectively, wherein a heating calibration turntable is disposed in the first triaxial Helmholtz coil and configured to heat and calibrate the directional sensor, and wherein a high-precision inclination and azimuth test turntable is disposed in the second triaxial Helmholtz coil and configured to verify the directional sensor.Type: ApplicationFiled: September 29, 2020Publication date: August 11, 2022Inventors: Zhuoran Meng, Jun Zhu, Fei Wang, Shuyun Cheng, Yao Wu, Sang Jia, Ying Guo, Hongsheng Cui, Yong Die, Ye Lu, Peng Chen, Tong Li, Jun Wang
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Publication number: 20220235786Abstract: A portable blowing device configured for being worn around a neck of a human body, includes two arms each defining an airflow channel therein; and fans received in the arms respectively. The arm includes an inner side wall close to the neck and an outer side wall connected to the inner side wall. The arm includes an air inlet and an air outlet in communication with the airflow channel respectively. The air inlet is arranged at the inner side wall and/or the outer side wall. The fan is configured to generate an airflow passing through the air inlet, the airflow channel and the air outlet in sequence.Type: ApplicationFiled: April 11, 2022Publication date: July 28, 2022Applicant: Shenzhen Lanhe Technologies Co., Ltd.Inventors: Kai LIU, Xunhuan WU, Guang YANG, Weiping LI, Quan LV, You LAI, Jun ZHU, Tong LI
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Publication number: 20220226334Abstract: An application of an antibody conjugate in the preparation of a drug for treating CD30 positive tumors, which is characterized in that: the antibody conjugate is F0002-ADC; the general formula of the structural thereof is Ab-Lm-Yn; and the CD30-positive tumors are CD30-positive tumors that express a multidrug resistance gene 1. In addition, a pharmaceutical combination and a pharmaceutical composition containing the antibody conjugate, which may be applied to the preparation of a drug used for treating CD30-positive tumors.Type: ApplicationFiled: May 21, 2019Publication date: July 21, 2022Inventors: Yijun SHEN, Tong YANG, Yanjun LIU, Qingsong GUO, Xuemei CAO, Hua LI, Bei GAO, Guanghao WU, Likai MENG, Yanbo GAO, Yang ZHU
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Patent number: 11386246Abstract: A method for designing a hybrid surface optical system comprises establishing a first initial system; keeping the first initial system unchanged and calculating a plurality of first feature data points, and fitting the first feature data points to obtain a spherical surface; repeating such steps until all spherical surfaces are obtained; calculating a plurality of second feature data points, and fitting the plurality of second feature data points to obtain an aspheric surface; repeating such steps until all aspheric surfaces are obtained; calculating a plurality of third feature data points, and fitting the plurality of third feature data points to obtain a freeform surface; repeating such steps until all freeform surfaces are obtained.Type: GrantFiled: December 14, 2017Date of Patent: July 12, 2022Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.Inventors: Jun Zhu, Tong-Tong Gong, Guo-Fan Jin, Shou-Shan Fan
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Publication number: 20220209995Abstract: A packet transmission method, device, and system are disclosed, and pertain to the field of network technologies. The system includes a first network device in a VPLS network and a second network device in a VPWS network. The first network device determines, based on a destination address carried in a received first packet, a virtual port corresponding to the destination address in a VPLS instance of the first network device, and sends the first packet to a second VPWS instance in the second network device based on the virtual port, where the virtual port is used to indicate a first VPWS instance in the first network device, and the second VPWS instance and the first VPWS instance are VPWS instances used to bear a same service.Type: ApplicationFiled: December 23, 2021Publication date: June 30, 2022Inventors: Haibo Wang, Xun Hu, Rongrong Hua, Tong Zhu
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Publication number: 20220210049Abstract: A packet processing method and a network device are provided. The method is applied to a network system, and the network system includes a first network device and a plurality of network devices separately connected to the first network device. The method includes: The first network device groups the plurality of network devices into a plurality of groups based on a service, where each of the plurality of groups includes at least one network device. The first network device determines one or more groups in the plurality of groups, and forwards packets of the service to one or more of the plurality of network devices in the one or more groups. In present application, a mode for forwarding the packets of the service can be flexibly selected according to a service requirement, to better meet the service requirement.Type: ApplicationFiled: December 21, 2021Publication date: June 30, 2022Inventors: Haibo WANG, Yi ZENG, Rongrong HUA, Tong ZHU
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Publication number: 20220210060Abstract: A packet transmission method, device, and system for network technologies are disclosed. A first network device receives, by using a first VPLS instance a packet to be sent to a user-side device connected to the second network device. The first network device forwards, based on an association relationship between the first VPLS instance and the first VPWS instance, the packet to a second VPWS instance in the second network device by using the first VPWS instance. A VPLS instance is associated with a VPWS instance in the first network device. A packet that is received by using the VPLS instance and that is to be sent to a user-side device can be forwarded by using the associated VPWS instance, so that pressure to learn a MAC address for packet transmission is reduced, and forwarding performance of the system is ensured.Type: ApplicationFiled: December 16, 2021Publication date: June 30, 2022Inventors: Haibo WANG, Xun Hu, Rongrong Hua, Tong Zhu
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Publication number: 20220159369Abstract: An electronic device includes a main body, a display disposed on the main body, and a sound-making assembly. The sound-making assembly includes a speaker box and a driving diaphragm located in the speaker box, the speaker box is disposed inside the main body or is formed using the main body and the display, where the main body includes a speaker grille corresponding to the speaker box, the driving diaphragm is fastened inside the speaker box and divides the speaker box into two sub-chambers, the speaker grille is coupled to one of the two sub-chambers, the driving diaphragm vibrates after receiving an audio signal, the driving diaphragm drives, through vibration of the driving diaphragm, air in the two sub-chambers to vibrate to make a sound, and the sound is propagated through the speaker grille.Type: ApplicationFiled: February 24, 2020Publication date: May 19, 2022Inventors: Jie Su, Tong Zhu, Ligang Yu, Chunjian Li