Patents by Inventor Tong Zhu

Tong Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210124819
    Abstract: A method includes: training a prediction model with sample data; obtaining user information of a user as an input feature to the prediction model; predicting, using the prediction model according to a set of determination conditions, whether the user has forgotten a payment password associated with a payment application; and in response to predicting that the user has forgotten the payment password and detecting the user logging in the payment application with a login password different from the payment password, displaying a user interface for directing the user to a payment password resetting interface for resetting the payment password.
    Type: Application
    Filed: January 4, 2021
    Publication date: April 29, 2021
    Inventors: Yipeng YANG, Kangbei JIANG, Ning WANG, Hua ZHAO, Tong ZHU
  • Patent number: 10992685
    Abstract: This disclosure relates to identity verification. In one aspect, a method includes obtaining verification information during a user application session of a user with an application component subsequent to a verification triggering request to perform identity verification on the user. A determination is made whether the verification information satisfies a first identity verification-free condition. When the verification information satisfies the first identity verification-free condition, an identity verification-free operation that does not include identity verification of the user is performed. When the verification information fails to satisfy the first identity verification-free condition, an identity verification process is performed to verify an identity of the user.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: April 27, 2021
    Assignee: Advanced New Technologies Co., Ltd.
    Inventors: Jue Mei, Xin Chen, Tong Zhu, Yiteng Tian
  • Patent number: 10967071
    Abstract: In one aspect, an active agent-conjugate, methods of preparing the active agent-conjugate, and uses thereof is provided.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: April 6, 2021
    Assignee: Concortis Biosystems, Corp.
    Inventors: Zhenwei Miao, Yufeng Hong, Tong Zhu, Alexander Wilhelm Chucholowski
  • Publication number: 20210052738
    Abstract: Provided are bispecific conjugates having the general formula: pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and their use in the treatment of cancer.
    Type: Application
    Filed: August 31, 2020
    Publication date: February 25, 2021
    Applicant: Sorrento Therapeutics, Inc.
    Inventors: James T. Patterson, Gunnar F. Kaufmann, Yanwen Fu, Tong Zhu
  • Patent number: 10925968
    Abstract: Provided herein are cell penetrating compounds having the Formula I: where, generally, each T is a thiol reactive group (e.g., a phosphorothioate), each L is a linker (e.g., a linear alkyl), and Y is a biologic (e.g., an antibody). Also provided are pharmaceutical compositions including the cell penetrating compounds, and methods of delivering the compound into a cell.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: February 23, 2021
    Assignee: Sorrento Therapeutics, Inc.
    Inventors: Yanwen Fu, Gunnar F. Kaufmann, Heehyoung Lee, Tong Zhu, Henry Hongjun Ji
  • Patent number: 10909233
    Abstract: A method includes: training a prediction model with sample data; obtaining user information of a user as an input feature to the prediction model; predicting, using the prediction model according to a set of determination conditions, whether the user has forgotten a payment password associated with a payment application; and in response to predicting that the user has forgotten the payment password and detecting the user logging in the payment application with a login password different from the payment password, displaying a user interface for directing the user to a payment password resetting interface for resetting the payment password.
    Type: Grant
    Filed: June 1, 2020
    Date of Patent: February 2, 2021
    Assignee: ADVANCED NEW TECHNOLOGIES CO., LTD.
    Inventors: Yipeng Yang, Kangbei Jiang, Ning Wang, Hua Zhao, Tong Zhu
  • Publication number: 20210017274
    Abstract: There is disclosed an improved ADC (antibody drug conjugate) type composition having at least two different drug payloads conjugated to a single targeting protein. More specifically, the present disclosure attaches a first drug conjugate to a dual Cysteine residue on a targeting protein and a second drug conjugate with a different drug to a Lys residue on the targeting protein.
    Type: Application
    Filed: September 29, 2020
    Publication date: January 21, 2021
    Applicant: Sorrento Therapeutics, Inc.
    Inventors: Zhenwei Miao, Gang Chen, Tong Zhu, Alisher B. Khasanov, Yufeng Hong, Hong D. Zhang, Alexander Chucholowski
  • Publication number: 20200382522
    Abstract: This disclosure relates to identity verification. In one aspect, a method includes obtaining verification information during a user application session of a user with an application component subsequent to a verification triggering request to perform identity verification on the user. A determination is made whether the verification information satisfies a first identity verification-free condition. When the verification information satisfies the first identity verification-free condition, an identity verification-free operation that does not include identity verification of the user is performed. When the verification information fails to satisfy the first identity verification-free condition, an identity verification process is performed to verify an identity of the user.
    Type: Application
    Filed: March 6, 2020
    Publication date: December 3, 2020
    Applicant: Alibaba Group Holding Limited
    Inventors: Jue Mei, Xin Chen, Tong Zhu, Yiteng Tian
  • Patent number: 10836821
    Abstract: There is disclosed an improved ADC (antibody drug conjugate) type composition having at least two different drug payloads conjugated to a single targeting protein. More specifically, the present disclosure attaches a first drug conjugate to a dual Cysteine residue on a targeting protein and a second drug conjugate with a different drug to a Lys residue on the targeting protein.
    Type: Grant
    Filed: October 15, 2014
    Date of Patent: November 17, 2020
    Assignee: Sorrento Therapeutics, Inc.
    Inventors: Zhenwei Miao, Gang Chen, Tong Zhu, Alisher B. Khasanov, Yufeng Hong, Hong D. Zhang, Alexander Chucholowski
  • Patent number: 10799598
    Abstract: Provided are bispecific conjugates having the general formula: pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and their use in the treatment of cancer.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: October 13, 2020
    Assignee: Sorrento Therapeutics, Inc.
    Inventors: James T. Patterson, Gunnar F. Kaufmann, Yanwen Fu, Tong Zhu
  • Publication number: 20200293647
    Abstract: A method includes: training a prediction model with sample data; obtaining user information of a user as an input feature to the prediction model; predicting, using the prediction model according to a set of determination conditions, whether the user has forgotten a payment password associated with a payment application; and in response to predicting that the user has forgotten the payment password and detecting the user logging in the payment application with a login password different from the payment password, displaying a user interface for directing the user to a payment password resetting interface for resetting the payment password.
    Type: Application
    Filed: June 1, 2020
    Publication date: September 17, 2020
    Inventors: Yipeng YANG, Kangbei JIANG, Ning WANG, Hua ZHAO, Tong ZHU
  • Patent number: 10590165
    Abstract: There is disclosed a Dolastatin derivative, conjugated to an antibody, comprising a Dolastatin derivative moiety of Formula IV.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: March 17, 2020
    Assignee: Sorrento Therapeutics, Inc.
    Inventors: Zhenwei Miao, Gang Chen, Tong Zhu, Alisher B. Khasanov, Dylan Deng, Hong Zhang
  • Publication number: 20190374651
    Abstract: Provided in the present invention are an anti-5T4 antibody-drug conjugate and the use thereof. In particular, provided in the present invention is an anti-5T4 antibody-drug conjugate. Also provided in the present invention are the pharmaceutical use of the anti-5T4 antibody-drug conjugate and the effect thereof in inhibiting or preventing tumors.
    Type: Application
    Filed: January 8, 2018
    Publication date: December 12, 2019
    Inventors: Zhenwei MIAO, Tong ZHU, Alisher B. KHASANOV, Sheldon CAO, Zhaohui LI, Min WU
  • Publication number: 20190358336
    Abstract: Provided herein are cell penetrating compounds having the Formula I: where, generally, each T is a thiol reactive group (e.g., a phosphorothioate), each L is a linker (e.g., a linear alkyl), and Y is a biologic (e.g., an antibody). Also provided are pharmaceutical compositions including the cell penetrating compounds, and methods of delivering the compound into a cell.
    Type: Application
    Filed: June 27, 2019
    Publication date: November 28, 2019
    Applicant: Sorrento Therapeutics, Inc.
    Inventors: Yanwen Fu, Gunnar F. Kaufmann, Heehyoung Lee, Tong Zhu, Henry Hongjun Ji
  • Publication number: 20190314321
    Abstract: The use of a genetic method to down-regulate RBO/EFR3/EFR3A/EFR3B proteins, TTC7 protein or PI4KIII? enzyme protein which interacts with RBO/EFR3/EFR3A/EFR3B proteins and TTC7 protein, or the use of a drug to inhibit PI4KIII? protein kinase activity reduces the accumulation of A?42 within neurons and age-dependent synaptic transmission failure and other obstacles in a fruit fly AD model, and obtains an effect of improving the learning and memory abilities of AD model mice. Provided is a method for using an RBO/EFR3/EFR3A/EFR3B inhibitor, a TTC7 inhibitor and a PI4KIII? inhibitor to treat Alzheimer's disease. Also provided is a method for screening a drug treating Alzheimer's disease by whether A? secretion by nerve cells is promoted or not.
    Type: Application
    Filed: May 3, 2016
    Publication date: October 17, 2019
    Inventors: Fude Huang, Xiao Zhang, Wenan Wang, Le Zhang, Lixiang Jiang, Tong Zhu, Haiyan Liu, Yudong Zhou, Yang He, Wanguo Wei
  • Publication number: 20190211093
    Abstract: The invention provides a liquid aqueous pharmaceutical formulation comprising a human anti-TNFa antibody, or antigen-binding portion thereof, which reduces pain associated with injection in a subject by at least about 50% when compared to injecting an otherwise identical formulation comprising at least one salt and/or at least one buffer. The invention also provides a liquid aqueous pharmaceutical formulation comprising a human anti-TNFa antibody, or antigen-binding portion thereof, having increased bioavailability upon subcutaneous administration into a subject. The formulation may comprise a therapeutic protein, such as a human anti-TNF-alpha antibody, or an antigen-binding portion thereof, or a biosimilar thereof.
    Type: Application
    Filed: August 10, 2018
    Publication date: July 11, 2019
    Inventors: Michael Neu, Markus Tschoepe, Carsten Weber, Wolfgang Fraunhofer, Laura Redden, Martin Gastens, Alexander Feick, Susan K. Paulson, Tong Zhu
  • Patent number: 10248980
    Abstract: A service processing device and method include receiving a service processing request including data interaction processing mode information and account information, and determining, based on the service processing request, one or more data interaction processing mode candidates for executing the service processing request. The data interaction processing mode candidates are determined from a plurality of data interaction processing modes. Each of the data interaction processing modes includes processing parameters, and at least one of the processing parameters is different between different data interaction processing modes. Each of the one or more data interaction processing mode candidates has an associated processing success rate based on a historical processing record of the data interaction processing modes.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: April 2, 2019
    Assignee: ALIBABA GROUP HOLDING LIMITED
    Inventors: Weijie Yan, Shuangfeng Li, Tong Zhu, Zidong He, Kai Xu
  • Publication number: 20190091345
    Abstract: An anti-HER2 antibody-drug conjugate or a pharmaceutically acceptable salt thereof, and an application of the anti-HER2 antibody-drug conjugate for preparing an antitumor pharmaceutical product.
    Type: Application
    Filed: February 4, 2017
    Publication date: March 28, 2019
    Inventors: Zhenwei MIAO, Tong ZHU, B. Khasanov ALISHER, Gang CHEN, Zhaohui LI, Sheldon CAO
  • Publication number: 20190096939
    Abstract: The present disclosure provides an image sensor, a color filter array, and a preparation method thereof. The method includes: etching a photosensitive array substrate to form a plurality of strip-shaped first color filters, arranged at intervals in a first direction, a width direction thereof being parallel to the first direction; and etching the photosensitive array substrate to form block-shaped second and third color filters, the second and third color filters being disposed within the intervals of the first color filters and distributed in a second direction alternately, wherein the first direction is perpendicular to the second direction. An RGB arrangement manner different from a traditional manner is proposed from the perspective of layout design, thereby breaking a single RGB layout arrangement manner and providing more space for RGB design.
    Type: Application
    Filed: August 21, 2018
    Publication date: March 28, 2019
    Inventors: Ming WU, Hsiao-Che WU, Tsung-Hsien LIN, Long Chiang WU, Chao XUE, Xiao-Tong ZHU
  • Publication number: 20190076438
    Abstract: The present invention provides an anti-ErbB2 antibody-drug conjugate, a composition comprising the conjugate, a method for preparing the conjugate, use of the conjugate.
    Type: Application
    Filed: November 22, 2016
    Publication date: March 14, 2019
    Applicant: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: Tongtong XUE, Zhenwei MIAO, Jing WANG, Gang CHEN, Yan QING, Tong ZHU, Liang XIAO, Hong ZHANG, Qiuyan YANG, Dylan Dalun DENG, Liping LIU, Hong ZENG, Li YIN, Qifeng SHI, Hongmei SONG, Xi ZHAO, Lichun WANG, Jingyi WANG