Abstract: The present invention provides a method for determining hydrogen sulfide (H2S) by headspace single-drop liquid phase microextraction and intelligent device colorimetry, which comprises: taking a silver-gold core-shell triangular nanosheet (Ag@Au TNS) as a nanodetection probe, in combination with an analysis method of headspace single-drop microextraction (HS-SDME), specifically extracting H2S volatilized from a sample to be detected by the nanodetection probe, and detecting H2S in the extracted sample with the help of the photographing function of an intelligent device and a color picking software. Compared with the prior art, the present invention adopts intelligent device colorimetry, with the limit of detection of about 65 nM and the linear range of 0.1-100 ?M, and the established method can be applied to the determination of H2S in actual samples such as egg white, milk and other opaque samples, and has the advantages of few procedures, simple operation, high detection efficiency and the like.

Abstract: A surgical instrument (10) includes a housing (20) defining a longitudinal axis and a first assembly (200) and a second assembly (300) operably coupled to the housing (20). The first assembly (200) includes a first function button (200b) pivotably coupled to the housing (20) about a first pivot (200p) and a first circuit (210) supported by the housing (20) and aligned with the first pivot (200p). The first function button (200b) includes a first arm (201) on a first side of the first pivot (200p) and a second arm (202) on a second side of the first pivot (200p). The first circuit (210) is aligned with the cutting picot between the first arm (201) and the second arm (202) and includes a first actuator (211) on the first side of the first pivot (200p) and a second actuator (212) on the second side of the first pivot (200p).

Abstract: A packet transmission method, device, and system are disclosed, and pertain to the field of network technologies. The system includes a first network device in a VPLS network and a second network device in a VPWS network. The first network device determines, based on a destination address carried in a received first packet, a virtual port corresponding to the destination address in a VPLS instance of the first network device, and sends the first packet to a second VPWS instance in the second network device based on the virtual port, where the virtual port is used to indicate a first VPWS instance in the first network device, and the second VPWS instance and the first VPWS instance are VPWS instances used to bear a same service.

Abstract: A photosensitive assembly includes a circuit board. The circuit board has a first surface, a second surface opposite to the first surface, and a first through hole extending through the first surface and the second surface. A photosensitive chip is disposed on the second surface. The photosensitive chip has a photosensitive area and a non-photosensitive area connected to the photosensitive area, the non-photosensitive area is electrically connected to one side of the second surface, and the photosensitive area is exposed from the first through hole. A reinforcing plate is disposed on the first surface. A thermal conductive layer is disposed on the photosensitive chip, and the thermal conductive layer includes a silica gel or a metal.

Abstract: This disclosure relates to antibody-drug conjugates (ADCs) comprising an anti-Trop-2 antibody. Provided herein are compositions comprising such ADCs, as well as methods of making and using the same.

Abstract: Provided is a preparation method of an antibody-drug conjugate represented by Formula (I), or a pharmaceutically acceptable salt or stereoisomer thereof, or a solvate of the foregoing, wherein A, X, Y, L, D and a are as defined herein.

Abstract: A radiative cooling apparatus including a layer of a material. The layer defines an exterior face. The material has a composition such that the layer is configured to reflect, at the exterior face, at least partly of the incoming electromagnetic radiation of at least some wavelengths in the solar spectrum. The layer is further configured to emit thermally-generated electromagnetic emission of at least some mid-infrared wavelengths out from the exterior face. Ceramics provided by embodiments of the invention could produce extra cooling effect without any electricity consumption, creating a prominent benefit to the energy saving of air conditioning systems of buildings.

Abstract: This application provides a communication method and apparatus. The method includes: A first communication apparatus receives a first EVPN MAC route from a second communication apparatus, where the first EVPN MAC route carries a first MAC address and a first VNI. The first communication apparatus generates a second EVPN MAC route based on the first EVPN MAC route, where the second EVPN MAC route carries the first MAC address and a first SID that is of the first communication apparatus and that corresponds to the first VNI. The first communication apparatus sends the second EVPN MAC route to a third communication apparatus. This application implements interconnection between a VXLAN and an SRv6 network.

Abstract: An electronic device includes a main body, a display disposed on the main body, and a sound-making assembly. The sound-making assembly includes a speaker box and a driving diaphragm located in the speaker box, the speaker box is disposed inside the main body or is formed using the main body and the display, where the main body includes a speaker grille corresponding to the speaker box, the driving diaphragm is fastened inside the speaker box and divides the speaker box into two sub-chambers, the speaker grille is coupled to one of the two sub-chambers, the driving diaphragm vibrates after receiving an audio signal, the driving diaphragm drives, through vibration of the driving diaphragm, air in the two sub-chambers to vibrate to make a sound, and the sound is propagated through the speaker grille.

Abstract: A packet transmission method, device, and system are disclosed, and pertain to the field of network technologies. The system includes a first network device in a VPLS network and a second network device in a VPWS network. The first network device determines, based on a destination address carried in a received first packet, a virtual port corresponding to the destination address in a VPLS instance of the first network device, and sends the first packet to a second VPWS instance in the second network device based on the virtual port, where the virtual port is used to indicate a first VPWS instance in the first network device, and the second VPWS instance and the first VPWS instance are VPWS instances used to bear a same service.

Abstract: The use of a genetic method to down-regulate RBO/EFR3/EFR3A/EFR3B proteins, TTC7 protein or PI4KIII? enzyme protein which interacts with RBO/EFR3/EFR3A/EFR3B proteins and TTC7 protein, or the use of a drug to inhibit PI4KIII? protein kinase activity reduces the accumulation of A?42 within neurons and age-dependent synaptic transmission failure and other obstacles in a fruit fly AD model, and obtains an effect of improving the learning and memory abilities of AD model mice. Provided is a method for using an RBO/EFR3/EFR3A/EFR3B inhibitor, a TTC7 inhibitor and a PI4KIII? inhibitor to treat Alzheimer's disease. Also provided is a method for screening a drug treating Alzheimer's disease by whether A? secretion by nerve cells is promoted or not.

Abstract: The present invention provides an anti-ErbB2 antibody-drug conjugate, a composition comprising the conjugate, a method for preparing the conjugate, and use of the conjugate.

Abstract: A packet transmission method, device, and system for network technologies are disclosed. A first network device receives, by using a first VPLS instance a packet to be sent to a user-side device connected to the second network device. The first network device forwards, based on an association relationship between the first VPLS instance and the first VPWS instance, the packet to a second VPWS instance in the second network device by using the first VPWS instance. A VPLS instance is associated with a VPWS instance in the first network device. A packet that is received by using the VPLS instance and that is to be sent to a user-side device can be forwarded by using the associated VPWS instance, so that pressure to learn a MAC address for packet transmission is reduced, and forwarding performance of the system is ensured.

Abstract: Provided in the present invention is an anti-5T4 antibody-drug conjugate and the use thereof. In particular, provided in the present invention is an anti-5T4 antibody-drug conjugate. Also provided in the present invention are the pharmaceutical use of the anti-5T4 antibody-drug conjugate and the effect thereof in inhibiting or preventing tumors.

Abstract: The present disclosure provides an innate immunity cell such as a gamma delta T (gdT) cell, Natural Killer (NK) cell, or macrophage having 2-[3-(1,3-dicarboxypropyl)ureido] pentanedioic acid (DUPA) chemically conjugated to the cell surface. The DUPA-conjugated cells provided herein demonstrate increased cytotoxicity toward cancer cells expressing PSMA. DUPA-conjugated cells can be primary cells or cells of a cell line. Also provided are methods of conjugating DUPA to the surface of NK cells, gamma delta T (gdT) cells, or macrophages and methods of treating cancer using DUPA-conjugated NK cells, gamma delta T (gdT) cells, or macrophages.

Abstract: A packet transmission method, device, and system are disclosed, and pertain to the field of network technologies. The system includes a first network device in a VPLS network and a second network device in a VPWS network. The first network device determines, based on a destination address carried in a received first packet, a virtual port corresponding to the destination address in a VPLS instance of the first network device, and sends the first packet to a second VPWS instance in the second network device based on the virtual port, where the virtual port is used to indicate a first VPWS instance in the first network device, and the second VPWS instance and the first VPWS instance are VPWS instances used to bear a same service.

Abstract: A packet processing method and a network device are provided. The method is applied to a network system, and the network system includes a first network device and a plurality of network devices separately connected to the first network device. The method includes: The first network device groups the plurality of network devices into a plurality of groups based on a service, where each of the plurality of groups includes at least one network device. The first network device determines one or more groups in the plurality of groups, and forwards packets of the service to one or more of the plurality of network devices in the one or more groups. In present application, a mode for forwarding the packets of the service can be flexibly selected according to a service requirement, to better meet the service requirement.

Abstract: A packet transmission method, device, and system for network technologies are disclosed. A first network device receives, by using a first VPLS instance a packet to be sent to a user-side device connected to the second network device. The first network device forwards, based on an association relationship between the first VPLS instance and the first VPWS instance, the packet to a second VPWS instance in the second network device by using the first VPWS instance. A VPLS instance is associated with a VPWS instance in the first network device. A packet that is received by using the VPLS instance and that is to be sent to a user-side device can be forwarded by using the associated VPWS instance, so that pressure to learn a MAC address for packet transmission is reduced, and forwarding performance of the system is ensured.

Abstract: An electronic device includes a main body, a display disposed on the main body, and a sound-making assembly. The sound-making assembly includes a speaker box and a driving diaphragm located in the speaker box, the speaker box is disposed inside the main body or is formed using the main body and the display, where the main body includes a speaker grille corresponding to the speaker box, the driving diaphragm is fastened inside the speaker box and divides the speaker box into two sub-chambers, the speaker grille is coupled to one of the two sub-chambers, the driving diaphragm vibrates after receiving an audio signal, the driving diaphragm drives, through vibration of the driving diaphragm, air in the two sub-chambers to vibrate to make a sound, and the sound is propagated through the speaker grille.

Abstract: There is disclosed an antibody drug conjugate (ADC) having an IgG antibody that binds to a CD38 target conjugated at a Cys site in the hinge region of an IgG antibody. There is further disclosed a method for treating multiple myeloma comprising providing an effective amount of a CD38 ADC.