Patents by Inventor Tongjie Wang

Tongjie Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RIC cell and preparation method therefor and use thereof
    Publication number: 20250129333
    Abstract: Provided are a RIC cell, and a preparation method therefor and application thereof. The present invention particularly relates to the lineage-specific differentiation of a pluripotent or multipotent stem cell, specifically to a RIC cell differentiated from a stem cell, and a preparation method therefor and application thereof.
    Type: Application
    Filed: July 11, 2022
    Publication date: April 24, 2025
    Applicants: INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES, BEIJING INSTITUTE FOR STEM CELL AND REGENERATIVE MEDICINE
    Inventors: Jinyong Wang, Dehao HUANG, Jianhuan LI, Fangxiao HU, Tongjie WANG, Chengxiang XIA, Baoyang HU, Jie HAO, Lei WANG, Liu WANG
  • Method for remolding bone marrow microenvironment
    Patent number: 10493106
    Abstract: The present invention discloses a method for remolding bone marrow microenvironment in a subject having an impaired bone marrow microenvironment, which comprises implanting a composition comprising isolated mesenchymal stromal cells (MSCs) into the bone marrow cavity of the subject. The method of the present invention successfully remolds the bone marrow microenvironment, recovers the normal hematopoiesis of bone marrow, inhibits/delays the pathological process of leukemia and significantly prolongs the survival period. In addition, the method according to the present invention can be used for the treatment of hematologic tumors such as leukemia and aplastic anemia (AA), which is safe and effective but has no side effects.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: December 3, 2019
    Assignee: GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES
    Inventors: Jinyong Wang, Chengxiang Xia, Yong Dong, Tongjie Wang, Xiaofei Liu, Juan Du, Yang Geng, Lijuan Liu, Hongling Wu
  • METHOD FOR REMOLDING BONE MARROW MICROENVIRONMENT
    Publication number: 20190111084
    Abstract: The present invention discloses a method for remolding bone marrow microenvironment in a subject having an impaired bone marrow microenvironment, which comprises implanting a composition comprising isolated mesenchymal stromal cells (MSCs) into the bone marrow cavity of the subject. The method of the present invention successfully remolds the bone marrow microenvironment, recovers the normal hematopoiesis of bone marrow, inhibits/delays the pathological process of leukemia and significantly prolongs the survival period. In addition, the method according to the present invention can be used for the treatment of hematologic tumors such as leukemia and aplastic anemia (AA), which is safe and effective but has no side effects.
    Type: Application
    Filed: January 12, 2018
    Publication date: April 18, 2019
    Inventors: Jinyong Wang, Chengxiang Xia, Yong Dong, Tongjie Wang, Xiaofei Liu, Juan Du, Yang Geng, Lijuan Liu, Hongling Wu