Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.

Abstract: An apparatus for charging a plurality of series connected battery cells, includes a first and second input terminals for providing a charging voltage to the plurality of series connected battery cell. A transformer includes a primary side associated with the charging voltage and a secondary side includes a plurality of portions. Each of the plurality of portions is connected across at least one of the plurality of series connected battery cell. A switch in series between each of the plurality of portions of the secondary side and the at least one of the plurality of series connected battery cells increases an impedance between the portion of the secondary side and the associated one of the plurality of series connected battery cells in a first state and decreases the impedance between the portion of the secondary side and the associated one of the plurality of series connected battery cells in a second state.

Abstract: An apparatus for charging a plurality of series connected battery cells, includes a first and second input terminals for providing a charging voltage to the plurality of series connected battery cell. A transformer includes a primary side associated with the charging voltage and a secondary side includes a plurality of portions. Each of the plurality of portions is connected across at least one of the plurality of series connected battery cell. A switch in series between each of the plurality of portions of the secondary side and the at least one of the plurality of series connected battery cells increases an impedance between the portion of the secondary side and the associated one of the plurality of series connected battery cells in a first state and decreases the impedance between the portion of the secondary side and the associated one of the plurality of series connected battery cells in a second state.

Abstract: A system includes a lift member configured to removably couple with a lifting device and a support member coupled to the lift member. The support member includes a first arm having a first end portion configured to removably engage a first section of an electronics panel, and a second arm having a second end portion offset by an arm distance from the first end portion. The second end portion is configured to selectively move to adjust the arm distance to removably engage a second section of the electronics panel opposite to the first section. The first and second end portions are configured to engage the electronics panel in a first orientation, to support the electronics panel during a transition to a second orientation, and to disengage the electronics panel in the second orientation.

Abstract: An apparatus for charging a plurality of series connected battery cells, includes a first and second input terminals for providing a charging voltage to the plurality of series connected battery cell. A transformer includes a primary side associated with the charging voltage and a secondary side includes a plurality of portions. Each of the plurality of portions is connected across at least one of the plurality of series connected battery cell. A switch in series between each of the plurality of portions of the secondary side and the at least one of the plurality of series connected battery cells increases an impedance between the portion of the secondary side and the associated one of the plurality of series connected battery cells in a first state and decreases the impedance between the portion of the secondary side and the associated one of the plurality of series connected battery cells in a second state.

Abstract: An apparatus for charging a plurality of series connected battery cells, includes a first and second input terminals for providing a charging voltage to the plurality of series connected battery cell. A transformer includes a primary side associated with the charging voltage and a secondary side includes a plurality of portions. Each of the plurality of portions is connected across at least one of the plurality of series connected battery cell. A switch in series between each of the plurality of portions of the secondary side and the at least one of the plurality of series connected battery cells increases an impedance between the portion of the secondary side and the associated one of the plurality of series connected battery cells in a first state and decreases the impedance between the portion of the secondary side and the associated one of the plurality of series connected battery cells in a second state.

Abstract: A system includes a lift member configured to removably couple with a lifting device and a support member coupled to the lift member. The support member includes a first arm having a first end portion configured to removably engage a first section of an electronics panel, and a second arm having a second end portion offset by an arm distance from the first end portion. The second end portion is configured to selectively move to adjust the arm distance to removably engage a second section of the electronics panel opposite to the first section. The first and second end portions are configured to engage the electronics panel in a first orientation, to support the electronics panel during a transition to a second orientation, and to disengage the electronics panel in the second orientation.

Abstract: A photobioreactor assembly, including panel having an array of equal radius, generally parallel, generally vertical and generally transparent tubes, where the tubes have a radius such that for a pre-determined microorganism preferred light intensity level, photosynthesis viable light is available at the center of each tube for an expected maximum culture density for that microorganism, an air supply operationally connected to panel and capable of maintaining a positive pressure within the panel, a water purifier operationally connected to the panel, and a water supply operationally connected to the water purifier. Each respective tube is connected in fluidic communication with each other.

Abstract: An apparatus for charging a plurality of series connected battery cells includes first and second input terminals for providing a charging voltage to the plurality of series connected battery cells. A transformer includes a primary side associated with the charging voltage and a secondary side including a plurality of portions. Each of the plurality of portions connected across at least two of the plurality of series connected battery cells. A first switch in series between each of the plurality of portions of the secondary side and a first battery cell of the at least two of the plurality of series connected battery cells provides a charging current to the first battery cell during a first portion of a cycle of a current in the primary side of the transformer.

Abstract: An electric toy snail comprises a shell mechanically coupled to a foot and a neck. The shell further comprises a power source and a compartment. The power source is electrically coupled to a motor, a light and a music device.

Abstract: An apparatus for charging a plurality of series connected battery cells includes first and second input terminals for providing a charging voltage to the plurality of series connected battery cells. A transformer includes a primary side associated with the charging voltage and a secondary side including a plurality of portions. Each of the plurality of portions connected across at least two of the plurality of series connected battery cells. A first switch in series between each of the plurality of portions of the secondary side and a first battery cell of the at least two of the plurality of series connected battery cells provides a charging current to the first battery cell during a first portion of a cycle of a current in the primary side of the transformer.

Abstract: An apparatus for charging a plurality of series connected battery cells, includes a first and second input terminals for providing a charging voltage to the plurality of series connected battery cell. A transformer includes a primary side associated with the charging voltage and a secondary side includes a plurality of portions. Each of the plurality of portions is connected across at least one of the plurality of series connected battery cell. A switch in series between each of the plurality of portions of the secondary side and the at least one of the plurality of series connected battery cells increases an impedance between the portion of the secondary side and the associated one of the plurality of series connected battery cells in a first state and decreases the impedance between the portion of the secondary side and the associated one of the plurality of series connected battery cells in a second state.

Abstract: A splined sleeve assembly is provided for use on a component support apparatus such as a clutch jack or the like. The support apparatus includes a base, a lift arm supported on the base for movement between a lowered position and a raised position, and a piston and cylinder assembly connected between the base and the lift arm for moving the lift arm between the lowered and raised positions. The support apparatus also includes a hinge plate supported on the lift arm for pivotal movement between raised and lowered positions, and the splined sleeve assembly includes a cylindrical support shaft adapted to be mounted on the hinge plate. A tubular sleeve presents a longitudinal axis and includes a cylindrical inner surface sized for axial and rotational sliding receipt on the support shaft, and an outer surface that includes a plurality of longitudinally extending splines adapted to engage a clutch or other component.