Abstract: Pharmaceutical compositions for treating viral, proliferative and inflammatory diseases are disclosed comprising an amount of pharmaceutically acceptable vitamin B12 compound in combination with an interferon compound. Vitamin B12 compounds are administered separately, simultaneously or in combination with interferon compounds to provide an enhanced therapeutic effect for treating viral, proliferative and inflammatory diseases.

Abstract: Pharmaceutical compositions for treating viral, proliferative and inflammatory diseases are disclosed comprising an amount of pharmaceutically acceptable vitamin B12 compounds in combination with anti-viral, anti-proliferative and anti-inflammatory compounds. Vitamin B12 compounds are administered separately, simultaneously or in combination with anti-viral, anti-proliferative and/or anti-inflammatory compounds to provide an enhanced therapeutic effect for treating viral, proliferative and inflammatory diseases.

Abstract: Photonic crystal structures are made by a method including steps of providing a substrate, depositing at least one planar layer to form a stack, each planar layer of the stack comprising two or more sublayers having different sublayer refractive indices, depositing a hard mask material, depositing an imprintable material over the hard mask material, patterning the imprintable material by imprinting an array of depressions, and directionally etching at the depressions a regular array of openings through the hard mask material and the stack.

Abstract: The present invention provides compositions and methods for treating a tissue disorder associated with a response-to-injury process or proliferating cells in a mammal. These tissue disorders are associated with a novel cellular phenotype designated as “transition cells” which are described herein. This cellular phenotype is characterized in having an activated erk kinase signaling activity, a stimulated AP-1 binding activity, and at least one characteristic selected from the group consisting of: (a) increased podosome formation, (b) increased flux of intracellular or extracellular hyaluronans or hyaladherins, (c) increased expression of a hyaladherin, (d) an inability to form focal adhesions, (e) increased metalloproteinase activity, and (f) increased expression of a hyaladherin. Example tissue disorders include fibrosis, inflammation, degeneration and invasive disorders such as occur in cancerous cells.

Abstract: Pharmaceutical compositions for treating viral, proliferative and inflammatory diseases are disclosed comprising an amount of pharmaceutically acceptable vitamin B12 compound in combination with an interferon compound. Vitamin B12 compounds are administered separately, simultaneously or in combination with interferon compounds to provide an enhanced therapeutic effect for treating viral, proliferative and inflammatory diseases.

Abstract: Pharmaceutical compositions for treating viral, proliferative and inflammatory diseases are disclosed comprising an amount of pharmaceutically acceptable vitamin B12 compounds in combination with anti-viral, anti-proliferative and anti-inflammatory compounds. Vitamin B12 compounds are administered separately, simultaneously or in combination with anti-viral, anti-proliferative and/or anti-inflammatory compounds to provide an enhanced therapeutic effect for treating viral, proliferative and inflammatory diseases.

Abstract: A method of dispensing a single ligament of fluid includes ejecting a first quantity of fluid from an inkjet dispenser toward a substrate, and ejecting a second quantity of fluid from the inkjet dispenser toward the substrate, wherein the second quantity of fluid is ejected from the inkjet dispenser at a frequency sufficient that the second quantity of fluid catches the first quantity of fluid thereby forming a single ligament of fluid prior to contacting the substrate.

Abstract: A method for producing porous structures in a three-dimensional object with solid freeform fabrication includes selectively depositing a removable support material, depositing a build material defining the three-dimensional object, and removing the selectively deposited removable support material to form a number of pores within the three-dimensional object.

Abstract: The present invention provides compositions and methods for treating a tissue disorder associated with a response-to-injury process or proliferating cells. They are associated with a novel cellular phenotype (designated “transition cells”) which is characterized in having an activated erk kinase signaling activity; a stimulated AP-1 binding activity; and increased podosome formation, increased flux of intracellular or extracellular hyaluronans or hyaladherins, increased expression of a hyaladherin, an inability to form focal adhesions, and/or increased metalloproteinase activity. A novel cell culture comprising transition cells is provided, as well as compositions and methods using particular peptides, polypeptides, and antibodies that affect the transitional phenotype.

Abstract: The present invention provides compositions and methods for treating a tissue disorder associated with a response-to-injury process or proliferating cells in a mammal. These tissue disorders are associated with a novel cellular phenotype designated as “transition cells” which are described herein. This cellular phenotype is characterized in having an activated erk kinase signaling activity, a stimulated AP-1 binding activity, and at least one characteristic selected from the group consisting of: (a) increased podosome formation, (b) increased flux of intracellular or extracellular hyaluronans or hyaladherins, (c) increased expression of a hyaladherin, (d) an inability to form focal adhesions, (e) increased metalloproteinase activity, and (f) increased expression of a hyaladherin. Example tissue disorders include fibrosis, inflammation, degeneration and invasive disorders such as occur in cancerous cells.

Abstract: A fluid dispensing system, including a photon source disposed on a moveable carriage and a fluid ejector array having a plurality of fluid ejection elements disposed on a substrate. Each fluid ejection element includes a fluid ejector, and a photodetector electrically coupled to the fluid ejector. Moving said photon source over at least a portion of the fluid ejector array, selectively illuminates the photodetectors, thereby selectively activating the fluid ejectors coupled to the illuminated photodetectors.

Abstract: The present invention provides compositions and methods for treating restenosis and autoimmune diseases. The methods provided herein include the administration of a composition comprising of the class of polypeptides, carbohydrates and/or extracts and their analogues, derivatives and conjugates, originating from the marine sponge Microciona prolifera.

Abstract: The present invention relates to the use of rhein or diacerhein compounds to treat and prevent vascular diseases that cause obstruction of the vascular system such as blood vessel restenosis and atherosclerosis.

Abstract: The present invention relates to the use of rhein or diacerhein compounds to treat and prevent vascular diseases that cause obstruction of the vascular system such as blood vessel restenosis and atherosclerosis.

Abstract: Pharmaceutical compositions for treating viral, proliferative and inflammatory diseases are disclosed comprising an amount of pharmaceutically acceptable vitamin B12 compounds in combination with anti-viral, anti-proliferative and anti-inflammatory compounds. Vitamin B12 compounds are administered separately, simultaneously or in combination with anti-viral, anti-proliferative and/or anti-inflammatory compounds to provide an enhanced therapeutic effect for treating viral, proliferative and inflammatory diseases.

Abstract: The present invention provides compositions and methods for treating a tissue disorder associated with a response-to-injury process or proliferating cells in a mammal. These tissue disorders are associated with a novel cellular phenotype designated as “transition cells” which are described herein. This cellular phenotype is characterized in having an activated erk kinase signaling activity, a stimulated AP-1 binding activity, and at least one characteristic selected from the group consisting of: (a) increased podosome formation, (b) increased flux of intracellular or extracellular hyaluronans or hyaladherins, (c) increased expression of a hyaladherin, (d) an inability to form focal adhesions, (e) increased metalloproteinase activity, and (f) increased expression of a hyaladherin. Example tissue disorders include fibrosis, inflammation, degeneration and invasive disorders such as occur in cancerous cells.

Abstract: Pharmaceutical compositions for treating viral, proliferative and inflammatory diseases are disclosed comprising an amount of pharmaceutically acceptable vitamin B12 compound in combination with an interferon compound. Vitamin B12 compounds are administered separately, simultaneously or in combination with interferon compounds to provide an enhanced therapeutic effect for treating viral, proliferative and inflammatory diseases.

Abstract: The present invention relates to the use of rhein or diacerhein compounds to treat and prevent vascular diseases that cause obstruction of the vascular system such as blood vessel restenosis and atherosclerosis.

Abstract: A drop detection apparatus has a thermosensitive substrate for receiving drops of ink and providing a signal representative of a change in the temperature in the thermosensitive substrate which is caused by the ink drops deposited on the thermosensitive substrate. The thermosensitive substrate is made from a pyroelectric material, such as, for example, polyvinylidene fluoride (PVDF) and lead zirconium titanate (PLZT). As a result, a drop detection apparatus has a substantially simplified structure for detecting drops of ink ejected from large numbers of jets. Furthermore, since a drop detection apparatus relies on the temperature difference between the thermosensitive substrate and the drop of ink which is substantially small in size, the drop detection apparatus can be made substantially small in size, therefore suitable for a small sized ink jet apparatus.

Abstract: The present invention relates to the use of vanadate compounds, or analogues of vanadate compounds, to treat arthropathies, and to compositions containing vanadate compounds adapted for such use.