Abstract: The present invention relates to materials, methods and kits for detecting and identifying glycated species, in particular methods in which glycated species are first labelled and then subjected to a separation step, following which the label may be directly detected.

Abstract: Materials and methods employing a polymerisable boronic acid species and a polymerisable linker are disclosed for making gels for resolving polyhydric species present in a sample by electrophoresis. The electrophoresis gels are capable of improving the effective separation of polyhydric species, especially those that show similar mobilities in standard electrophoresis or fluorophore-assisted carbohydrate electrophoresis (FACE). The use of template molecules in the reaction to form the electrophoresis gel with the boronic acid species and the polymerisable linker, so that the template molecule becomes incorporated into the electrophoresis gel, is also disclosed. The template molecule provides cavities in the electrophoresis gel that are generally complementary to the template molecule and which are adapted to reversibly interact with one or more of the polyhydric species present in the sample that have structures similar to the template molecule.

Abstract: A method for detecting the presence and/or amount of fluoride in a test sample which comprises contacting the test sample with a compound of Formula (1) or a salt thereof and evaluating any change in the spectral characteristics of the compound: