Patents by Inventor Tony H. Ko
Tony H. Ko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11006825Abstract: Optical Coherence Tomography Angiography (OCTA) image representation is obtained having OCTA pixels assigned respective OCTA values. A vessel density map is computed from the OCTA image representation. A fractional deviation map and/or a pattern deviation map is computed for the patient from the vessel density map and a normative database, wherein: (1) the fractional deviation map represents a percent loss of vessel density at each pixel location relative to an expected value based on the normative database; and (2) computing the pattern deviation map includes: computing a pattern map of the vessel density representing a normalized vessel density pattern of the vessel density map relative to an average value of the vessel density map; and computing the pattern deviation map using the pattern map. A loss is determined by using at least one of the fractional deviation map and the pattern deviation map. Other features are also provided.Type: GrantFiled: February 1, 2019Date of Patent: May 18, 2021Assignee: OPTOVUE, INC.Inventors: Jay Wei, Tony H. Ko, Yi-Sing Hsiao, Ben Jang, Richard Rosen
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Patent number: 10743762Abstract: An ophthalmologic apparatus according to the embodiments includes an OCT optical system, an alignment unit, an image forming unit, a first calculator, and a second calculator. The OCT optical system is configured to acquire OCT data of a fundus of a subject's eye by projecting measurement light onto the fundus. The alignment unit is configured to perform alignment of the OCT optical system with reference to a predetermined site of the subject's eye. The image forming unit is configured to form a tomographic image of the fundus based on the OCT data acquired by the OCT optical system which has been aligned by the alignment unit. The first calculator is configured to calculate a first tilt angle of the tomographic image. The second calculator is configured to calculate a second tilt angle of the fundus by correcting the first tilt angle based on alignment result of the OCT optical system with respect to the predetermined site by the alignment unit.Type: GrantFiled: September 28, 2018Date of Patent: August 18, 2020Assignee: TOPCON CORPORATIONInventors: Hitoshi Shimizu, Masashi Nakajima, Tony H. Ko, Jonathan Liu, Yasufumi Fukuma
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Publication number: 20200100673Abstract: An ophthalmologic apparatus according to the embodiments includes an OCT optical system, an alignment unit, an image forming unit, a first calculator, and a second calculator. The OCT optical system is configured to acquire OCT data of a fundus of a subject's eye by projecting measurement light onto the fundus. The alignment unit is configured to perform alignment of the OCT optical system with reference to a predetermined site of the subject's eye. The image forming unit is configured to form a tomographic image of the fundus based on the OCT data acquired by the OCT optical system which has been aligned by the alignment unit. The first calculator is configured to calculate a first tilt angle of the tomographic image. The second calculator is configured to calculate a second tilt angle of the fundus by correcting the first tilt angle based on alignment result of the OCT optical system with respect to the predetermined site by the alignment unit.Type: ApplicationFiled: September 28, 2018Publication date: April 2, 2020Applicant: TOPCON CORPORATIONInventors: Hitoshi SHIMIZU, Masashi Nakajima, Tony H. Ko, Jonathan Liu, Yasufumi Fukuma
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Publication number: 20190167099Abstract: A method of processing a 3D OCT dataset is present. A method according to some embodiments of the present invention includes obtaining an OCT data from the 3D OCT dataset; obtaining an OCTA data from the 3D OCT dataset; performing segmentation for at least one boundary on the OCT data; processing the OCTA data in a region of interest to create at least one image representation by assigning a value to each pixel of each of the image representation; and displaying at least one image representation.Type: ApplicationFiled: February 1, 2019Publication date: June 6, 2019Inventors: Jay Wei, Tony H. Ko, Yi-Sing Hsiao, Ben Jang, Richard Rosen
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Patent number: 10258231Abstract: A method of processing a 3D OCT dataset is present. A method according to some embodiments of the present invention includes obtaining an OCT data from the 3D OCT dataset; obtaining an OCTA data from the 3D OCT dataset; performing segmentation for at least one boundary on the OCT data; processing the OCTA data in a region of interest to create at least one image representation by assigning a value to each pixel of each of the image representation; and displaying at least one image representation.Type: GrantFiled: December 30, 2015Date of Patent: April 16, 2019Assignee: OPTOVUE, INC.Inventors: Jay Wei, Tony H. Ko, Yi-Sing Hsiao, Ben Jang, Richard Rosen
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Patent number: 10194866Abstract: In some embodiments of the present invention, a method of reducing artifacts includes obtaining OCT/OCTA data from an OCT/OCTA imager; preprocessing OCTA/OCT volume data; extracting features from the preprocessed OCTA/OCT volume data; classifying the OCTA/OCT volume data to provide a probability determination data; determining a percentage data from the probability data determination; and reducing artifacts in response to the percentage data.Type: GrantFiled: February 17, 2017Date of Patent: February 5, 2019Assignee: OPTOVUE, INC.Inventors: Yi-Sing Hsiao, Ben K. Jang, Utkarsh Sharma, Qienyuan Zhou, Tony H. Ko, Jay Wei
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Publication number: 20170238877Abstract: In some embodiments of the present invention, a method of reducing artifacts includes obtaining OCT/OCTA data from an OCT/OCTA imager; preprocessing OCTA/OCT volume data; extracting features from the preprocessed OCTA/OCT volume data; classifying the OCTA/OCT volume data to provide a probability determination data; determining a percentage data from the probability data determination; and reducing artifacts in response to the percentage data.Type: ApplicationFiled: February 17, 2017Publication date: August 24, 2017Inventors: Yi-Sing HSIAO, Ben K. JANG, Utkarsh SHARMA, Qienyuan ZHOU, Tony H. KO, Jay WEI
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Patent number: 9492078Abstract: An imager that can provide separated images corresponding to differing depths in a sample is presented. In accordance with some embodiments of the invention, an imager can include a light source; a sample arm that receives light from the light source, directs the light to a sample, and captures light returning from the sample; a modulation source that provides different modulations corresponding to differing imaging depths in the sample; a detector system to receive the captured light from the sample with the different modulations; and a processor that receives signals from the detector system and separates a plurality of images corresponding with the differing image depths in the sample.Type: GrantFiled: December 9, 2013Date of Patent: November 15, 2016Assignee: OPTOVUE, INC.Inventors: Tony H. Ko, Yonghua Zhao, David Huang
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Patent number: 9411149Abstract: Micro-optical imaging is facilitated. According to an example embodiment, a micro-optical probe arrangement includes a GRIN-type lens probe to direct light to and from a specimen. Compensation optics tailored to the probe and aberrations introduced by the lens are located in a light path through the lens, and compensate for the introduced aberrations. A light detector detects light from the specimen, as facilitated by the compensation optics, and generates data characterizing an image of the specimen.Type: GrantFiled: July 17, 2008Date of Patent: August 9, 2016Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Benjamin A. Flusberg, Mark Jacob Schnitzer, Tony H. Ko
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Publication number: 20160183786Abstract: A method of processing a 3D OCT dataset is present. A method according to some embodiments of the present invention includes obtaining an OCT data from the 3D OCT dataset; obtaining an OCTA data from the 3D OCT dataset; performing segmentation for at least one boundary on the OCT data; processing the OCTA data in a region of interest to create at least one image representation by assigning a value to each pixel of each of the image representation; and displaying at least one image representation.Type: ApplicationFiled: December 30, 2015Publication date: June 30, 2016Inventors: Jay Wei, Tony H. Ko, Yi-Sing Hsiao, Ben Jang, Richard Rosen
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Publication number: 20140160430Abstract: An imager that can provide separated images corresponding to differing depths in a sample is presented. In accordance with some embodiments of the invention, an imager can include a light source; a sample arm that receives light from the light source, directs the light to a sample, and captures light returning from the sample; a modulation source that provides different modulations corresponding to differing imaging depths in the sample; a detector system to receive the captured light from the sample with the different modulations; and a processor that receives signals from the detector system and separates a plurality of images corresponding with the differing image depths in the sample.Type: ApplicationFiled: December 9, 2013Publication date: June 12, 2014Applicant: Optovue, Inc.Inventors: Tony H. KO, Yonghua Zhao, David Huang
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Patent number: 8605287Abstract: An imager that can provide separated images corresponding to differing depths in a sample is presented. In accordance with some embodiments of the invention, an imager can include a light source; a sample arm that receives light from the light source, directs the light to a sample, and captures light returning from the sample; a modulation source that provides different modulations corresponding to differing imaging depths in the sample; a detector system to receive the captured light from the sample with the different modulations; and a processor that receives signals from the detector system and separates a plurality of images corresponding with the differing image depths in the sample.Type: GrantFiled: July 21, 2009Date of Patent: December 10, 2013Assignee: Optovue, Inc.Inventors: Tony H. Ko, Yonghua Zhao, David Huang
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Publication number: 20120274783Abstract: An optical coherence tomography system is provided. The system includes an OCT imager; a two-dimensional transverse scanner coupled to the OCT imager, the two-dimensional transverse scanner receiving light from the light source and coupling reflected light from a sample into the OCT imager; optics that couple light between the two-dimensional transverse scanner and the sample; a video camera coupled to the optics and acquiring images of the sample; and a computer coupled to receive images of the sample from the video camera, the computer processing the images and providing a motion offset signal based on the images to the two-dimensional transverse scanner.Type: ApplicationFiled: April 27, 2012Publication date: November 1, 2012Applicant: OPTOVUE, INC.Inventors: Tony H. KO, Xingzhi LUO, Yonghua ZHAO, Ben JANG
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Publication number: 20100033727Abstract: An imager that can provide separated images corresponding to differing depths in a sample is presented. In accordance with some embodiments of the invention, an imager can include a light source; a sample arm that receives light from the light source, directs the light to a sample, and captures light returning from the sample; a modulation source that provides different modulations corresponding to differing imaging depths in the sample; a detector system to receive the captured light from the sample with the different modulations; and a processor that receives signals from the detector system and separates a plurality of images corresponding with the differing image depths in the sample.Type: ApplicationFiled: July 21, 2009Publication date: February 11, 2010Inventors: Tony H. Ko, Yonghua Zhao, David Huang