Abstract: Integrated modular liquid handling systems are described. The modular liquid handling systems may be customized for use in a variety of applications, including sample processing, assays, diagnostic analyses, and separation of biomolecules. The liquid handling systems may include a variety of integrated modules that provide functions including dispensing of liquids, aspiration of liquids, sensing of liquid parameters, and detection of signals.

Abstract: In a method and magnetic resonance apparatus to reduce distortions in magnetic resonance diffusion imaging, a magnetic resonance data acquisition system is operated to acquire magnetic resonance data in a first measurement with a first diffusion weighting, and to acquire magnetic resonance data in a second measurement with a second, different diffusion weighting. A non-linear, system-specific distortion-correcting function is determined on the basis of system-specific information that is specific to said magnetic resonance data acquisition system. Correction parameters are calculated to correct distortions in subsequently-acquired diffusion-weighted magnetic resonance images, based on the data acquired in the first and second measurements with the system-specific distortion-correcting function applied thereto. The subsequently-acquired diffusion-weighted magnetic resonance images are corrected using the correction parameters to at least reduce distortions therein.

Abstract: In a method and apparatus to reduce distortions in diffusion imaging, at least one first measurement is implemented with a first diffusion weighting for a number of slices that are spatially separated from one another and at least one second measurement is implemented with a second diffusion weighting for the number of slices that are spatially separated from one another. A deskewing function is determined as are correction parameters to deskew diffusion-weighted magnetic resonance images on the basis of the measurements, so that image information and/or correction parameters of different slices are linked with one another. The diffusion-weighted magnetic resonance images are distortion-corrected on the basis of the deskewing function and the correction parameters.

Abstract: In a method and apparatus to reduce distortions in diffusion imaging, at least one first measurement is implemented with a first diffusion weighting for a number of slices that are spatially separated from one another and at least one second measurement is implemented with a second diffusion weighting for the number of slices that are spatially separated from one another. A deskewing function is determined as are correction parameters to deskew diffusion-weighted magnetic resonance images on the basis of the measurements, so that image information and/or correction parameters of different slices are linked with one another. The diffusion-weighted magnetic resonance images are distortion-corrected on the basis of the deskewing function and the correction parameters.

Abstract: In a method and magnetic resonance apparatus to reduce distortions in magnetic resonance diffusion imaging, a magnetic resonance data acquisition system is operated to acquire magnetic resonance data in a first measurement with a first diffusion weighting, and to acquire magnetic resonance data in a second measurement with a second, different diffusion weighting. A non-linear, system-specific distortion-correcting function is determined on the basis of system-specific information that is specific to said magnetic resonance data acquisition system. Correction parameters are calculated to correct distortions in subsequently-acquired diffusion-weighted magnetic resonance images, based on the data acquired in the first and second measurements with the system-specific distortion-correcting function applied thereto. The subsequently-acquired diffusion-weighted magnetic resonance images are corrected using the correction parameters to at least reduce distortions therein.