Patents by Inventor TONY R. HUNTER

TONY R. HUNTER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating neurodegenerative diseases
    Publication number: 20040123334
    Abstract: An animal model for neurodegenerative disorders, e.g., a transgenic model in which the Pin1 gene is misexpressed is described. The animal is useful for identifying and monitoring treatments and agents for a number of neurodegenerative disorders. Accordingly, also provided are methods for preventing, treating and/or delaying the onset of neurodegenerative disorders by administering to a subject in need thereof and agent that increases Pin1 biological activity in neuronal tissues and fluids.
    Type: Application
    Filed: January 12, 2004
    Publication date: June 24, 2004
    Applicants: BETH ISRAEL DEACONESS MEDICAL CENTER, The Salk Institute for Biological Studies
    Inventors: Kun Ping Lu, Tony R. Hunter, Yih-Cherng Liou
  • Peptidyl-prolyl cis-trans isomerase inhibitors and uses therefor
    Publication number: 20030096387
    Abstract: The invention relates to inhibitors of PPIase activity and pharmaceutical compositions containing such inhibitors. Such compounds are useful for treatment of disorders characterized by inappropriate cell proliferation. In particular the compounds disclosed herein inhibit the activity of members of the Pin1/parvulin class of PPIases. These compounds have been designed based on the high resolution X-Ray derived crystal structure of the human enzyme Pin1.
    Type: Application
    Filed: October 28, 2002
    Publication date: May 22, 2003
    Applicant: The Salk institute for Biological Studies
    Inventors: Joseph P. Noel, Tony R. Hunter
  • PEDTIDYL-PROLYL CIS-TRANS ISOMERASE INHIBITORS AND USES THEREFORE
    Publication number: 20010016346
    Abstract: The invention relates to inhibitors of PPIase activity and pharmaceutical compositions containing such inhibitors. Such compounds are useful for treatment of disorders characterized by inappropriate cell proliferation. In particular the compounds disclosed herein inhibit the activity of members of the Pinl/parvulin class of PPIases. These compounds have been designed based on the high resolution X-Ray derived crystal structure of the human enzyme Pin1.
    Type: Application
    Filed: June 9, 1998
    Publication date: August 23, 2001
    Inventors: JOSEPH P. NOEL, TONY R. HUNTER