Patents by Inventor Tony Rowe

Tony Rowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antioxidant stabilized crosslinked ultra high molecular weight polyethylene for medical device applications
    Patent number: 10556998
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: February 11, 2020
    Assignee: Zimmer, Inc.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Werner Schneider, Hallie E Brinkerhuff
  • Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
    Patent number: 9926432
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: March 27, 2018
    Assignee: Zimmer, Inc.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Hallie E Brinkerhuff, Werner Schneider
  • ANTIOXIDANT STABILIZED CROSSLINKED ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS
    Publication number: 20180051141
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Application
    Filed: October 13, 2017
    Publication date: February 22, 2018
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Werner Schneider, Hallie E. Brinkerhuff
  • Antioxidant stabilized crosslinked ultra high molecular weight polyethylene for medical device applications
    Patent number: 9822224
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: November 21, 2017
    Assignee: Zimmer, Inc.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Werner Schneider, Hallie E Brinkerhuff
  • ANTIOXIDANT STABILIZED CROSSLINKED ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS
    Publication number: 20160145416
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Application
    Filed: December 29, 2015
    Publication date: May 26, 2016
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Hallie E. Brinkerhuff, Werner Schneider
  • ANTIOXIDANT STABILIZED CROSSLINKED ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS
    Publication number: 20160108184
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation, In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Application
    Filed: December 22, 2015
    Publication date: April 21, 2016
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Werner Schneider, Hallie E. Brinkerhuff
  • Antioxidant stabilized crosslinked ultra high molecular weight polyethylene for medical device applications
    Patent number: 9277949
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: March 8, 2016
    Assignee: Zimmer, Inc.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Werner Schneider, Hallie E Brinkerhuff
  • Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
    Patent number: 9265545
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: February 23, 2016
    Assignee: Zimmer, Inc.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Hallie E Brinkerhuff, Werner Schneider
  • Treatment of cancer involving mutated KRAS or BRAF genes
    Patent number: 8932588
    Abstract: The present invention provides a method of treating cancer in a subject wherein the cancer comprises mutated KRAS or BRAF genes. The method comprises administering to the subject an effective amount of an antibody or antigen binding fragment thereof wherein the antibody or antigen binding fragment thereof competes with SC104 for binding to the human colon cancer cell line Colo205.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: January 13, 2015
    Assignee: Teva Pharmaceuticals Australia Pty. Ltd.
    Inventors: Norbert A. Kienzle, Anthony G. Doyle, Tony Rowe
  • ANTIOXIDANT STABILIZED CROSSLINKED ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS
    Publication number: 20140194935
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Application
    Filed: January 17, 2014
    Publication date: July 10, 2014
    Applicant: Zimmer, Inc.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Hallie E. Brinkerhuff, Werner Schneider
  • ANTIOXIDANT STABALIZED CROSSLINKED ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS
    Publication number: 20140194934
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Application
    Filed: January 17, 2014
    Publication date: July 10, 2014
    Applicant: Zimmer, Inc.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Werner Schneider, Hallie E. Brinkerhuff
  • Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
    Patent number: 8669299
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: March 11, 2014
    Assignee: Zimmer, Inc.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Werner Schneider, Hallie E. Brinkerhuff
  • Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
    Patent number: 8664290
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: March 4, 2014
    Assignee: Zimmer, Inc.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Werner Schneider, Hallie E. Brinkerhuff
  • Treatment of Cancer Involving Mutated KRAS or BRAF Genes
    Publication number: 20120244151
    Abstract: The present invention provides a method of treating cancer in a subject wherein the cancer comprises mutated KRAS or BRAF genes. The method comprises administering to the subject an effective amount of an antibody or antigen binding fragment thereof wherein the antibody or antigen binding fragment thereof competes with SC104 for binding to the human colon cancer cell line Colo205.
    Type: Application
    Filed: October 29, 2010
    Publication date: September 27, 2012
    Applicant: Cephalon Australia PTY LTD
    Inventors: Norbert A. Kienzle, Anthony G. Doyle, Tony Rowe
  • Antioxidant Stabilized Crosslinked Ultra-High Molecular Weight Polyethylene For Medical Device Applications
    Publication number: 20120157591
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Application
    Filed: February 23, 2012
    Publication date: June 21, 2012
    Applicant: Zimmer, Inc.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Hallie E. Brinkerhuff, Werner Schneider
  • Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
    Patent number: 8178594
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: May 15, 2012
    Assignee: Zimmer, Inc.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Werner Schneider, Hallie E. Brinkerhuff
  • Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
    Patent number: 8129440
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: March 6, 2012
    Assignee: Zimmer, Inc.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Werner Schneider, Hallie E. Brinkerhuff
  • ANTIOXIDANT STABILIZED CROSSLINKED ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS
    Publication number: 20110133371
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Application
    Filed: December 14, 2010
    Publication date: June 9, 2011
    Applicant: ZIMMER, INC.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Hallie E. Brinkerhuff, Werner Schneider
  • ANTIOXIDANT STABILIZED CROSSLINKED ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS
    Publication number: 20110028600
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Application
    Filed: July 30, 2010
    Publication date: February 3, 2011
    Applicant: ZIMMER, INC.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Werner Schneider, Hallie E. Brinkerhuff
  • ANTIOXIDANT STABILIZED CROSSLINKED ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS
    Publication number: 20100029858
    Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.
    Type: Application
    Filed: October 14, 2009
    Publication date: February 4, 2010
    Applicant: ZIMMER, INC.
    Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Hallie E. Brinkerhuff, Werner Schneider