Patents by Inventor Tony W. Liang

Tony W. Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR CONJUGATING ACTIVATABLE ANTIBODIES
    Publication number: 20220088192
    Abstract: The invention relates generally to compositions and methods for conjugating antibodies and activatable antibodies, and methods of partially reducing antibodies and/or activatable antibodies prior to conjugation, e.g., thiol-based conjugation, with an agent, e.g., a therapeutic and/or diagnostic agent.
    Type: Application
    Filed: April 9, 2021
    Publication date: March 24, 2022
    Inventors: Henry Bernard LOWMAN, Luc Roland DESNOYERS, Tony W. LIANG, Andrei William KONRADI, Shweta SINGH
  • Antibodies that bind activatable antibodies and methods of use thereof
    Patent number: 10568977
    Abstract: The invention relates generally to antibodies and antigen-binding fragments thereof that bind activatable antibodies and/or conjugated activatable antibodies and methods of making and using these antibodies that bind activatable antibodies and/or conjugated activatable antibodies.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: February 25, 2020
    Assignee: CytomX Therapeutics, Inc.
    Inventors: Luc Roland Desnoyers, Tony W. Liang, Annie Yang Weaver
  • ANTIBODIES THAT BIND ACTIVATABLE ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20170326260
    Abstract: The invention relates generally to antibodies and antigen-binding fragments thereof that bind activatable antibodies and/or conjugated activatable antibodies and methods of making and using these antibodies that bind activatable antibodies and/or conjugated activatable antibodies.
    Type: Application
    Filed: July 26, 2017
    Publication date: November 16, 2017
    Inventors: Luc Roland Desnoyers, Tony W. Liang, Annie Yang Weaver
  • Antibodies that bind activatable antibodies and methods of use thereof
    Patent number: 9737623
    Abstract: The invention relates generally to antibodies and antigen-binding fragments thereof that bind activatable antibodies and/or conjugated activatable antibodies and methods of making and using these antibodies that bind activatable antibodies and/or conjugated activatable antibodies.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: August 22, 2017
    Assignee: CYTOMX THERAPEUTICS, INC.
    Inventors: Luc Roland Desnoyers, Tony W. Liang, Annie Yang Weaver
  • COMPOSITIONS AND METHODS FOR CONJUGATING ACTIVATABLE ANTIBODIES
    Publication number: 20170072067
    Abstract: The invention relates generally to compositions and methods for conjugating antibodies and activatable antibodies, and methods of partially reducing antibodies and/or activatable antibodies prior to conjugation, e.g., thiol-based conjugation, with an agent, e.g., a therapeutic and/or diagnostic agent.
    Type: Application
    Filed: November 22, 2016
    Publication date: March 16, 2017
    Inventors: Henry Bernard Lowman, Luc Roland Desnoyers, Tony W. Liang, Andrei William Konradi, Shweta Singh
  • Compositions and methods for conjugating activatable antibodies
    Patent number: 9517276
    Abstract: The invention relates generally to compositions and methods for conjugating antibodies and activatable antibodies, and methods of partially reducing antibodies and/or activatable antibodies prior to conjugation, e.g., thiol-based conjugation, with an agent, e.g., a therapeutic and/or diagnostic agent.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: December 13, 2016
    Assignee: CYTOMX THERAPEUTICS, INC.
    Inventors: Henry Bernard Lowman, Luc Roland Desnoyers, Tony W. Liang, Andrei William Konradi, Shweta Singh
  • Antibodies that Bind Activatable Antibodies and Methods of Use Thereof
    Publication number: 20150157748
    Abstract: The invention relates generally to antibodies and antigen-binding fragments thereof that bind activatable antibodies and/or conjugated activatable antibodies and methods of making and using these antibodies that bind activatable antibodies and/or conjugated activatable antibodies.
    Type: Application
    Filed: December 11, 2014
    Publication date: June 11, 2015
    Inventors: Luc Roland Desnoyers, Tony W. Liang, Annie Yang Weaver
  • COMPOSITIONS AND METHODS FOR CONJUGATING ACTIVATABLE ANTIBODIES
    Publication number: 20150005477
    Abstract: The invention relates generally to compositions and methods for conjugating antibodies and activatable antibodies, and methods of partially reducing antibodies and/or activatable antibodies prior to conjugation, e.g., thiol-based conjugation, with an agent, e.g., a therapeutic and/or diagnostic agent.
    Type: Application
    Filed: June 4, 2014
    Publication date: January 1, 2015
    Inventors: Henry Bernard Lowman, Luc Roland Desnoyers, Tony W. Liang, Andrei William Konradi, Shweta Singh
  • KID3 and KID3 antibodies that bind thereto
    Patent number: 8440197
    Abstract: The invention provides the identification and characterization of disease and cancer-associated epitope, KID3. The invention also provides a family of monoclonal antibodies that bind to KID3, methods of diagnosing and treating various human cancers and diseases that express KID3.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: May 14, 2013
    Assignee: MacroGenics, Inc.
    Inventors: Tony W. Liang, Deryk T. Loo, Xiaolin Xu
  • TES7 and antibodies that bind thereto
    Patent number: 8216570
    Abstract: The invention provides the identification and characterization of a disease and cancer-associated antigen, TES7. The invention also provides a family of monoclonal antibodies that bind to antigen TES7, methods of diagnosing and treating various human cancers and diseases with TES7.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: July 10, 2012
    Assignee: MacroGenics, Inc.
    Inventors: Jennie P. Mather, Tony W. Liang
  • KID3 and KID3 Antibodies That Bind Thereto
    Publication number: 20100322851
    Abstract: The invention provides the identification and characterization of disease and cancer-associated epitope, KID3. The invention also provides a family of monoclonal antibodies that bind to KID3, methods of diagnosing and treating various human cancers and diseases that express KID3.
    Type: Application
    Filed: July 7, 2010
    Publication date: December 23, 2010
    Applicant: MacroGenics, Inc.
    Inventors: Tony W. Liang, Deryk T. Loo, Xiaolin Xu
  • KID3 and KID3 antibodies that bind thereto
    Patent number: 7790855
    Abstract: The invention provides the identification and characterization of disease and cancer-associated epitope, KID3. The invention also provides a family of monoclonal antibodies that bind to KID3, methods of diagnosing and treating various human cancers and diseases that express KID3.
    Type: Grant
    Filed: September 17, 2004
    Date of Patent: September 7, 2010
    Assignee: MacroGenics, Inc.
    Inventors: Tony W. Liang, Deryk T. Loo, Xiaolin Xu
  • TES7 AND ANTIBODIES THAT BIND THERETO
    Publication number: 20100183605
    Abstract: The invention provides the identification and characterization of a disease and cancer-associated antigen, TES7. The invention also provides a family of monoclonal antibodies that bind to antigen TES7, methods of diagnosing and treating various human cancers and diseases with TES7.
    Type: Application
    Filed: March 16, 2010
    Publication date: July 22, 2010
    Applicant: MACROGENICS, INC.
    Inventors: Jennie P. Mather, Tony W. Liang
  • TES7 and antibodies that bind thereto
    Patent number: 7718774
    Abstract: The invention provides the identification and characterization of disease and cancer-associated antigen, TES7. The invention also provides a family of monoclonal antibodies that bind to antigen TES7, methods of diagnosing and treating various human cancers and diseases that express TES7.
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: May 18, 2010
    Assignee: MacroGenics, Inc.
    Inventors: Jennie P. Mather, Tony W. Liang
  • TES7 AND ANTIBODIES THAT BIND THERETO
    Publication number: 20080226634
    Abstract: The invention provides the identification and characterization of disease and cancer-associated antigen, TES7. The invention also provides a family of monoclonal antibodies that bind to antigen TES7, methods of diagnosing and treating various human cancers and diseases that express TES7.
    Type: Application
    Filed: November 8, 2007
    Publication date: September 18, 2008
    Inventors: Jennie P. MATHER, Tony W. LIANG
  • Antigen PIPA and antibodies that bind thereto
    Patent number: 7405061
    Abstract: Provided herein is disclosure about the identification and characterization of disease and cancer associated antigen PIPA. The invention also provides a family of monoclonal antibodies that bind to antigen PIPA, and methods of diagnosing and treating various human cancers and diseases that express PIPA.
    Type: Grant
    Filed: November 13, 2003
    Date of Patent: July 29, 2008
    Assignee: Raven biotechnologies, inc.
    Inventors: Jennie P. Mather, Ronghao Li, Tony W. Liang
  • Antigen PIPA and antibodies that bind thereto
    Publication number: 20040171814
    Abstract: Provided herein is disclosure about the identification and characterization of disease and cancer associated antigen PIPA. The invention also provides a family of monoclonal antibodies that bind to antigen PIPA, and methods of diagnosing and treating various human cancers and diseases that express PIPA.
    Type: Application
    Filed: November 13, 2003
    Publication date: September 2, 2004
    Inventors: Jennie P. Mather, Ronghao Li, Tony W. Liang