Patents by Inventor Tony Yaksh

Tony Yaksh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATIONS FOR THE DELIVERY OF ACTIVE INGREDIENTS
    Publication number: 20190374644
    Abstract: This invention relates generally to in vivo delivery of active ingredient formulations. More particularly, this invention relates to formulations of active ingredients that further comprise an agent, methods of making such formulations, and methods of using the same.
    Type: Application
    Filed: August 27, 2019
    Publication date: December 12, 2019
    Inventors: Julien MAMET, Scott HARRIS, George MILJANICH, Rick ORR, William K. SCHMIDT, Tony YAKSH, David C. YEOMANS
  • Formulations for the delivery of active ingredients
    Patent number: 10434178
    Abstract: This invention relates generally to in vivo delivery of active ingredient formulations. More particularly, this invention relates to formulations of active ingredients that further comprise an agent, methods of making such formulations, and methods of using the same.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: October 8, 2019
    Assignee: Adynxx Sub, Inc.
    Inventors: Julien Mamet, Scott Harris, George Miljanich, Rick Orr, William K. Schmidt, Tony Yaksh, David C. Yeomans
  • FORMULATIONS FOR THE DELIVERY OF ACTIVE INGREDIENTS
    Publication number: 20180015165
    Abstract: This invention relates generally to in vivo delivery of active ingredient formulations. More particularly, this invention relates to formulations of active ingredients that further comprise an agent, methods of making such formulations, and methods of using the same.
    Type: Application
    Filed: April 5, 2017
    Publication date: January 18, 2018
    Applicant: Adynxx, Inc.
    Inventors: Julien Mamet, Scott Harris, George Miljanich, Rick Orr, William K. Schmidt, Tony Yaksh, David C. Yeomans
  • Formulations for the delivery of active ingredients
    Patent number: 9700624
    Abstract: This invention relates generally to in vivo delivery of active ingredient formulations. More particularly, this invention relates to formulations of active ingredients that further comprise an agent, methods of making such formulations, and methods of using the same.
    Type: Grant
    Filed: May 9, 2013
    Date of Patent: July 11, 2017
    Assignee: Adynxx, Inc.
    Inventors: Julien Mamet, Scott Harris, George Miljanich, Rick Orr, William K Schmidt, Tony Yaksh, David C Yeomans
  • Compositions and methods for inhibition of phospholipase A2 mediated inflammation
    Patent number: 7745489
    Abstract: Specific, highly potent 2-oxo-amide based inhibitors of phospholipase A2 (PLA2) activity are provided. A role for PLA2 activity in spinally mediated inflammatory processes is established, and a method for treating hyperalgesia and other inflammatory conditions associated with PLA2 activity is provided.
    Type: Grant
    Filed: March 7, 2003
    Date of Patent: June 29, 2010
    Assignee: The Regents of the University of California
    Inventors: Edward Dennis, Tony Yaksh, Karin Killermann Lucas, Camilla Svensson, David A. Six, George Kokotos, Violetta Constantinou-Kokotou
  • Systemic and Intrathecal Effects of a Novel Series of Phospholipase A2 Inhibitors on Hyperalgesia and Spinal Pge2 Release
    Publication number: 20080319065
    Abstract: Phospholipase A2 (PLA2) forins are expressed in spinal cord whose inhibition induces a potent antihyperalgesia. PLA2 inhibitor compounds are provided that include a common motif consisting of a 2-oxoamide with a hydrocarbon tail and a four carbon tether. The compounds block Group IVA calcium dependent PLA2 (cPLA2) and/or Group VIA calcium independent PLA2 (iPLA2) and/or Group V secreted PLA2 (sPLA2).
    Type: Application
    Filed: August 17, 2006
    Publication date: December 25, 2008
    Inventors: Edward Dennis, Tony Yaksh, Karin Killerman Lucas, Camilla Svensson, David A. Six, George Kokots, Violetta Constantinou-Kokotou
  • Treatment of pain by inhibition of p38 map kinase
    Publication number: 20080039461
    Abstract: The present invention relates to methods for the prevention or treatment of pain by the inhibition of p38 MAP kinase.
    Type: Application
    Filed: December 28, 2006
    Publication date: February 14, 2008
    Inventors: Andrew Protter, Camilla Svensson, Tony Yaksh, Barbara Cordell, Sundeep Dugar
  • Apparatus and method for detecting flinch response to nociceptive agents
    Patent number: 6996429
    Abstract: An apparatus and method for measuring spatial displacement of an animal's paw injected with irritant. This apparatus comprises an electromagnetic detecting assembly having (1) a transmitting oscillator for generating electrical current (2) an electromagnetic transmitter coil coupled to the oscillator for generating an electromagnetic field (3) an electromagnetic receiving coil placed in axial plane directly below the transmitter coil (4) a first, receiving amplifier connected to the receiving coil (5) an amplitude detector connected to the receiving amplifier (6) a second amplifier connected to the amplitude detector (7) a metal object attached to the animal's paw (8) and a cylindrical observation chamber of a diameter not greater than the diameter of the generated magnetic field.
    Type: Grant
    Filed: January 17, 2001
    Date of Patent: February 7, 2006
    Assignee: Regents of the Univeristy of California, San Diego
    Inventors: Tony Yaksh, George Ozaki
  • Compositions and methods for inhibition of phospholipase a2 mediated inflammation
    Publication number: 20050148549
    Abstract: Specific, highly potent 2-oxo-amide based inhibitors of phospholipase A2 (PLA2) activity are provided. A role for PLA2 activity in spinally mediated inflammatory processes is established, and a method for treating hyperalgesia and other inflammatory conditions associated with PLA2 activity is provided.
    Type: Application
    Filed: March 7, 2003
    Publication date: July 7, 2005
    Inventors: Edward Dennis, Tony Yaksh, Karin Lucas, Camilla Svensson, David Six, George Kokotos, Violetta Constaninou-Kokotou
  • Treatment of pain by inhibition of p38 MAP kinase
    Publication number: 20040122008
    Abstract: The present invention relates to methods for the prevention or treatment of pain by the inhibition of p38 MAP kinase.
    Type: Application
    Filed: September 5, 2003
    Publication date: June 24, 2004
    Inventors: Andrew A. Protter, Camilla Svensson, Tony Yaksh, Barbara Cordell, Sundeep Dugar
  • Apparatus and method for detecting flinch response to nociceptive agents
    Publication number: 20030233041
    Abstract: An apparatus and method for measuring spatial displacement of an animal's paw injected with irritant. This apparatus comprises an electromagnetic detecting assembly having (1) a transmitting occilator for generating electrical current (2) an electromagnetic transmitter coil coupled to the occilator for generating an electromagnetic field (3) an electromagnetic receiving coil placed in axial plane directly below the transmitter coil (4) a first, receiving amplifier connected to the receiving coil (5) an amplitude detector connected to the receiving amplifier (6) a second amplifier connected to the amplitude detector (7) a metal object attached to the animal's paw (8) and a cylindrical observation chamber of a diameter not greater than the diameter of the generated magnetic field.
    Type: Application
    Filed: January 17, 2001
    Publication date: December 18, 2003
    Inventors: Tony Yaksh, George Ozaki