Abstract: The present invention is a device for protecting against needlestick injuries, including a syringe, a sheath, an actuator, and a button. The syringe has a tube, plunger, and a needle in a hub. The sheath covers the needle in a first position, and the needle protrudes from a hole in the sheath in a second position. The plunger can be pressed to dispense from the tube in the second position. The actuator controls the movement between positions, and the button is the manual control for activating the actuator. The syringe extends through the sheath and actuator, such that the sheath and actuator can be adjusted for any type of syringe. A single hand can operate the button and the plunger.