Patents by Inventor Torben Lessman

Torben Lessman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prodrugs comprising an insulin linker conjugate
    Patent number: 9138462
    Abstract: The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof comprising an insulin linker conjugate D-L1, wherein D is insulin; and -L1 is: wherein the dashed line indicates the attachment to one of the amino groups of the insulin by forming an amide bond. The invention further relates to pharmaceutical compositions comprising said prodrugs as well as their use as a medicament for treating or preventing diseases or disorders which can be treated by insulin.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: September 22, 2015
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Harald Rau, Felix Cleemann, Ulrich Hersel, Silvia Kaden-Vagt, Torben Lessman, Thomas Wegge
  • Prodrugs comprising an exendin linker conjugate
    Patent number: 9133276
    Abstract: The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof comprising an exendin linker conjugate D-L1, wherein D represents an exendin moiety; and -L1 is represented by formula (I), wherein the dashed line indicates the attachment to one of the amino groups of the exendin moiety by forming an amide bond. The invention further relates to pharmaceutical compositions comprising said prodrugs as well as their use as a medicament for treating or preventing diseases or disorders which can be treated by exendin.
    Type: Grant
    Filed: September 16, 2011
    Date of Patent: September 15, 2015
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Felix Cleemann, Ulrich Hersel, Torben Lessman, Harald Rau
  • PRODRUGS COMPRISING AN EXENDIN LINKER CONJUGATE
    Publication number: 20130189328
    Abstract: The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof comprising an exendin linker conjugate D-L, wherein D represents an exendin moiety; and -L is a non-biologically active linker moiety -L1 represented by formula (I), wherein the dashed line indicates the attachment to one of the amino groups of the exendin moiety by forming an amide bond. The invention further relates to pharmaceutical compositions comprising said prodrugs as well as their use as a medicament for treating or preventing diseases or disorders which can be treated by exendin.
    Type: Application
    Filed: September 16, 2011
    Publication date: July 25, 2013
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Felix Cleemann, Ulrich Hersel, Torben Lessman, Harald Rau
  • PRODRUGS COMPRISING AN INSULIN LINKER CONJUGATE
    Publication number: 20120184489
    Abstract: The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof comprising an insulin linker conjugate D-L, wherein D represents the insulin moiety; and -L is a non-biologically active linker moiety -L1 represented by formula (I), wherein the dashed line indicates the attachment to one of the amino groups of the insulin by forming an amide bond. The invention further relates to pharmaceutical compositions comprising said prodrugs as well as their use as a medicament for treating or preventing diseases or disorders which can be treated by insulin.
    Type: Application
    Filed: July 30, 2010
    Publication date: July 19, 2012
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Harald Rau, Felix Cleeman, Ulrich Hersel, Silvia Kaden-Vagt, Torben Lessman