Abstract: A method for real-time analysis and measurement of temporal tissue variations and ultrasonic signals which provides quality improvement of tissue images and qualitative and quantitative characterization of the size/shape of the imaged objects is described. A given number of image frames are stored and made available for digital data analysis. For each spatial coordinate, the temporal signal evolution or a derived temporal signal evolution is extracted. These evolutions are analyzed digitally and the resulting image can be displayed on a display unit as an improved 2D tissue image and/or an indicator image for a particular tissue or fluid category in the imaged scene. The resulting image can be further processed with a spatial filter investigating a plurality of neighboring scan lines and a plurality of neighboring ranges at each image coordinate and finally thresholded in order to obtain a binary indicator of the imaged objects that are detected in the combined time and space characterization.