Abstract: A clinical decision support system and method for improving treatment of a medical condition includes determining a current best practice treatment for the medical condition, deriving a perturbed variation of the current best practice treatment, identifying a plurality of new treatment outcomes resulting from treatment of a plurality of patients via the perturbed variation of the current best practice treatment, and deriving a new best practice treatment based on the plurality of new treatment outcomes. The perturbed variation of the current best practice may be small enough so as not to require patient consent, or may be sufficiently large so as to require patient consent.

Abstract: A method of imaging a blood vessel in a body using X-rays and an injectable contrast medium is described. The contrast medium is injected into the body, and signals constituted by an X-ray image sequence depicting X-ray attenuation values is recorded. The X-ray attenuated values in each spaced-time neighborhood are combined in a way that is dependent on the processed image sequence and separately established for each neighborhood, and separating, from background and vessel signals, flow signals having energy contributions mainly in an area of frequency domain bounded by surfaces corresponding to threshold velocities separately established for each neighborhood, which surfaces are shifted a specified amount along a temporal frequency axis.