Patents by Inventor Tore Curstedt

Tore Curstedt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYPEPTIDES HAVING IMPROVED PROPERTIES
    Publication number: 20230257446
    Abstract: The present invention is directed to polypeptides having the properties of both SP-C and SP-B surfactant proteins and to the corresponding reconstituted surfactants. The invention is also directed to the pharmaceutical compositions thereof and to their use for the treatment or prophylaxis of neonatal respiratory distress syndrome (RDS) or other respiratory disorders such as acute RDS.
    Type: Application
    Filed: January 26, 2021
    Publication date: August 17, 2023
    Inventors: Tore CURSTEDT, Jan JOHANSSON
  • Reconstituted surfactants having improved properties
    Patent number: 9238058
    Abstract: Reconstituted surfactants comprising a lipid carrier, a polypeptide analog of the native surfactant protein SP-C, and a polypeptide analog of the native surfactant protein SP-B are useful for the treatment and/or prophylaxis of RDS and other respiratory disorders.
    Type: Grant
    Filed: April 10, 2012
    Date of Patent: January 19, 2016
    Assignee: CHIESI FARMACEUTICI S.p.A.
    Inventors: Jan Johansson, Tore Curstedt, Joakim Robertson, Soeren Robertson, Magnus Robertson, Charlotte Robertson, Gertie Robertson Grossmann
  • Reconstituted pulmonary surfactants
    Patent number: 9074018
    Abstract: The present invention is directed to a reconstituted surfactant comprising a phospholipid mixture, and a combination of particular analogues of the native surfactant protein SP-C with analogues of the native surfactant protein SP-B. The invention is also directed to pharmaceutical compositions and kits thereof and to its use for the treatment or prophylaxis of RDS and other respiratory disorders.
    Type: Grant
    Filed: November 20, 2013
    Date of Patent: July 7, 2015
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Jan Johansson, Tore Curstedt
  • RECONSTITUTED PULMONARY SURFACTANTS
    Publication number: 20140142021
    Abstract: The present invention is directed to a reconstituted surfactant comprising a phospholipid mixture, and a combination of particular analogues of the native surfactant protein SP-C with analogues of the native surfactant protein SP-B. The invention is also directed to pharmaceutical compositions and kits thereof and to its use for the treatment or prophylaxis of RDS and other respiratory disorders.
    Type: Application
    Filed: November 20, 2013
    Publication date: May 22, 2014
    Applicant: CHIESI FARMACEUTICI S.p.A
    Inventors: JAN JOHANSSON, TORE CURSTEDT
  • RECONSTITUTED SURFACTANTS HAVING IMPROVED PROPERTIES
    Publication number: 20130079275
    Abstract: Reconstituted surfactants comprising a lipid carrier, a polypeptide analog of the native surfactant protein SP-C, and a polypeptide analog of the native surfactant protein SP-B are useful for the treatment and/or prophylaxis of RDS and other respiratory disorders.
    Type: Application
    Filed: April 10, 2012
    Publication date: March 28, 2013
    Applicant: CHIESI FARMACEUTICI S.p.A.
    Inventors: JAN JOHANSSON, TORE CURSTEDT, LENA STALAND JONSSON, JOAKIM ROBERTSON, SOEREN ROBERTSON, MAGNUS ROBERTSON, CHARLOTTE ROBERTSON, GERTIE ROBERTSON GROSSMANN
  • Reconstituted surfactants having improved properties
    Patent number: 8183210
    Abstract: Reconstituted surfactants comprising a lipid carrier, a polypeptide analog of the native surfactant protein SP-C, and a polypeptide analog of the native surfactant protein SP-B are useful for the treatment and/or prophylaxis of RDS and other respiratory disorders.
    Type: Grant
    Filed: April 13, 2009
    Date of Patent: May 22, 2012
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Jan Johansson, Tore Curstedt, Bengt Robertson, Joakim Robertson, legal representative, Soeren Robertson, legal representative, Magnus Robertson, legal representative, Charlotte Robertson, legal representative, Gertie Robertson Grossmann, legal representative
  • Synthetic pulmonary surfactant peptides
    Patent number: 8148492
    Abstract: The present invention is directed to a reconstituted surfactant comprising a lipid carrier, a polypeptide analog of the native surfactant protein SP-C, and a polypeptide analog of the native surfactant protein SP-B. The invention is also directed to the pharmaceutical compositions thereof and to a use thereof in the treatment or prophylaxis of RDS and other respiratory disorders.
    Type: Grant
    Filed: August 11, 2008
    Date of Patent: April 3, 2012
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Jan Johansson, Tore Curstedt, Bengt Robertson, Maurlzio Delcanale
  • Reconstituted surfactants having improved properties
    Patent number: 7897577
    Abstract: The present invention is directed to a reconstituted surfactant containing a lipid carrier, a polypeptide analog of the native surfactant protein SP-C, and a polypeptide comprising a sequence comprised of repeated units where each unit contains between 3 and 8 hydrophobic amino acid residues and one basic amino acid residue. The invention is also directed to the pharmaceutical compositions thereof and to its use for the prophylaxis and/or treatment of RDS and other respiratory disorders.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: March 1, 2011
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Jan Johansson, Tore Curstedt, Bengt Robertson
  • Synthetic lipid mixtures for the preparation of a reconstituted surfactant
    Patent number: 7842664
    Abstract: The invention relates to reconstituted surfactants consisting of artificial phospholipids and peptides able to lower the air-liquid surface tension, more particularly to reconstituted surfactants comprising special phospholipid mixtures and artificial peptides which are analogues of the natural surfactant SP-C protein for the treatment of respiratory distress syndrome (RDS) and other diseases relating to pulmonary surfactant dysfunctions.
    Type: Grant
    Filed: March 6, 2008
    Date of Patent: November 30, 2010
    Assignee: Chiesi Farmaceutici S.p.A
    Inventors: Tore Curstedt, Jan Johansson, Bengt Robertson
  • Lipid mixtures for synthetic surfactants
    Patent number: 7811988
    Abstract: The present invention provides novel lipid mixtures for synthetic surfactants. In particular, the invention provides a specific lipid mixture containing a specific amount of polyunsaturated phospholipids to be used for the preparation of synthetic surfactants. Said surfactants and pharmaceutical compositions thereof are useful for the treatment of surfactant deficiencies like respiratory distress syndrome (RDS).
    Type: Grant
    Filed: May 26, 2004
    Date of Patent: October 12, 2010
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Jan Johansson, Tore Curstedt, Bengt Robertson
  • RECONSTITUTED SURFACTANTS HAVING IMPROVED PROPERTIES
    Publication number: 20100004173
    Abstract: Reconstituted surfactants comprising a lipid carrier, a polypeptide analog of the native surfactant protein SP-C, and a polypeptide analog of the native surfactant protein SP-B are useful for the treatment and/or prophylaxis of RDS and other respiratory disorders.
    Type: Application
    Filed: April 13, 2009
    Publication date: January 7, 2010
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Jan JOHANSSON, Tore Curstedt, Bengt Robertson, Joakim Robertson, Soeren Robertson, Magnus Robertson, Charlotte Robertson, Gertie Robertson Grossmann
  • COMPOSITIONS COMPRISING PULMONARY SURFACTANTS AND A POLYMYXIN HAVING IMPROVED SURFACE PROPERTIES
    Publication number: 20090170758
    Abstract: Pulmonary surfactants comprising additives, such as polymyxins, that improve their surface tension lowering properties. A method for improving the resistance to inactivation of a modified natural surfactant, such as one containing a lipid extract of minced mammalian lung comprising administering a surfactant in combination with a polymyxin.
    Type: Application
    Filed: December 29, 2008
    Publication date: July 2, 2009
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Jan Johansson, Tore Curstedt, Bengt Robertson
  • RECONSTITUTED SURFACTANTS HAVING IMPROVED PROPERTIES
    Publication number: 20090088379
    Abstract: The present invention is directed to a reconstituted surfactant containing a lipid carrier, a polypeptide analog of the native surfactant protein SP-C, and a polypeptide comprising a sequence comprised of repeated units where each unit contains between 3 and 8 hydrophobic amino acid residues and one basic amino acid residue. The invention is also directed to the pharmaceutical compositions thereof and to its use for the prophylaxis and/or treatment of RDS and other respiratory disorders.
    Type: Application
    Filed: June 2, 2008
    Publication date: April 2, 2009
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Jan Johansson, Tore Curstedt, Bengt Robertson
  • Synthetic lipid mixtures for the preparation of a reconstituted surfactant
    Patent number: 7511011
    Abstract: The invention relates to reconstituted surfactants consisting of artificial phospholipids and peptides able to lower the air-liquid surface tension, more particularly to reconstituted surfactants, comprising special phospholipid mixtures and artificial peptides which are analogues of the natural surfactant SP-C protein for the treatment of respiratory distress syndrome (RDS) and other diseases relates to pulmonary surfactant dysfunctions.
    Type: Grant
    Filed: May 12, 2003
    Date of Patent: March 31, 2009
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Tore Curstedt, Jan Johansson, Bengt Robertson
  • Synthetic pulmonary surfactant peptides
    Publication number: 20090075892
    Abstract: The present invention is directed to a reconstituted surfactant comprising a lipid carrier, a polypeptide analog of the native surfactant protein SP-C, and a polypeptide analog of the native surfactant protein SP-B. The invention is also directed to the pharmaceutical compositions thereof and to a use thereof in the treatment or prophylaxis of RDS and other respiratory disorders.
    Type: Application
    Filed: August 11, 2008
    Publication date: March 19, 2009
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Jan Johansson, Tore Curstedt, Bengt Robertson, Maurizio Delcanale
  • SYNTHETIC LIPID MIXTURES FOR THE PREPARATION OF A RECONSTITUTED SURFACTANT
    Publication number: 20080242589
    Abstract: The invention relates to reconstituted surfactants consisting of artificial phospholipids and peptides able to lower the air-liquid surface tension, more particularly to reconstituted surfactants comprising special phospholipid mixtures and artificial peptides which are analogues of the natural surfactant SP-C protein for the treatment of respiratory distress syndrome (RDS) and other diseases relating to pulmonary surfactant dysfunctions.
    Type: Application
    Filed: March 6, 2008
    Publication date: October 2, 2008
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Tore CURSTEDT, Jan Johansson, Bengt Robertson
  • Novel Lipid Mixtures For Synthetic Surfactants
    Publication number: 20080045449
    Abstract: The present invention provides novel lipid mixtures for synthetic surfactants. In particular, the invention provides a specific lipid mixture containing a specific amount of polyunsaturated phospholipids to be used for the preparation of synthetic surfactants. Said surfactants and pharmaceutical compositions thereof are useful for the treatment of surfactant deficiencies like respiratory distress syndrome (RDS).
    Type: Application
    Filed: May 26, 2004
    Publication date: February 21, 2008
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Jan Johansson, Tore Curstedt, Bengt Robertson
  • Artificial peptides having surface activity and the use thereof in the preparation of artificial surfactant
    Patent number: 7053044
    Abstract: SP-C analogue artificial peptides having surface activity are disclosed and their use for preparing artificial surfactants useful in the treatment of respiratory distress syndrome (RDS) and other diseases related to surfactant deficiency or dysfunction.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: May 30, 2006
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Tore Curstedt, Jan Johansson, Hans Jörnvall, Paolo Ventura
  • Compositions comprising pulmonary surfactants and a polymyxin having improved surface properties
    Publication number: 20050203008
    Abstract: This invention is directed to pulmonary surfactants comprising additives for improving their surface tension lowering properties, and to the use of additives for improving the properties of modified natural surfactants or reconstituted/artificial surfactants. More particularly this invention is directed to the use of polymyxins for increasing the resistance to inactivation of modified natural surfactants or reconstituted/artificial surfactants and/or increasing their activity.
    Type: Application
    Filed: February 26, 2003
    Publication date: September 15, 2005
    Applicant: Chiesi Farmaceutici S.p.A
    Inventors: Jan Johansson, Tore Curstedt, Bengt Robertson
  • Synthetic lipid mixtures for the preparation of a reconstituted surfactant
    Publication number: 20050176625
    Abstract: The invention relates to reconstituted surfactants consisting of artificial phospholipids and peptides able to lower the air-liquid surface tension, more particularly to reconstituted surfactants, comprising special phospholipid mixtures and artificial peptides which are analogues of the natural surfactant SP-C protein for the treatment of respiratory distress syndrome (RDS) and other diseases relates to pulmonary surfactant dysfunctions.
    Type: Application
    Filed: May 12, 2003
    Publication date: August 11, 2005
    Applicant: CHIESI FARMACEUTICI S.P.A.
    Inventors: Tore Curstedt, Jan Johansson, Bengt Robertson