Patents by Inventor Torsten BUSCH

Torsten BUSCH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters
    Patent number: 10196406
    Abstract: The present invention relates to a process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters thereof of formula (I) in high yields starting from a dialkyl ketal derivative of formula (V)
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: February 5, 2019
    Assignee: EUTICALS S.P.A.
    Inventors: Michael Nonnenmacher, Torsten Busch
  • PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS
    Publication number: 20170305937
    Abstract: The present invention relates to a process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters thereof of formula (I) in high yields starting from a dialkyl ketal derivative of formula (V)
    Type: Application
    Filed: July 13, 2017
    Publication date: October 26, 2017
    Inventors: Michael Nonnenmacher, Torsten Busch
  • Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters
    Patent number: 9738663
    Abstract: The present invention relates to a process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters thereof of formula (I) in high yield. The claimed process uses diarylketal formula (V) to generate an arylbromide of formula (III) in which the amino-group is protected as bisarylmethylidenimino-group, which is then transformed into a formula (I) compound.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: August 22, 2017
    Assignee: EUTICALS S.P.A.
    Inventors: Michael Nonnenmacher, Torsten Busch
  • PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS
    Publication number: 20160075723
    Abstract: The present invention relates to a process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters thereof of formula (I) in high yield. The claimed process uses diarylketal formula (V) to generate an arylbromide of formula (III) in which the amino-group is protected as bisarylmethylidenimino-group, which is then transformed into a formula (I) compound.
    Type: Application
    Filed: April 30, 2014
    Publication date: March 17, 2016
    Inventors: Michael Nonnenmacher, Torsten Busch
  • Process for preparing spiro[2.5]octane-5,7-dione
    Patent number: 9212120
    Abstract: Disclosed is a method for the synthesis of spiro[2.5]octane-5,7-dione useful as intermediate in the manufacture of pharmaceutically active ingredients. Also disclosed are novel intermediates used in the synthesis of this compound.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: December 15, 2015
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Torsten Busch, Sven Anklam, Joerg Jung, Markus Ostermeier
  • Process for the preparation of boronic acid intermediates
    Patent number: 9102689
    Abstract: The present invention relates to a process for the preparation of 2-amino-pyrimidine-5-boronic acid of formula (I). or salts or esters thereof.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: August 11, 2015
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Torsten Busch, Michael Nonnenmacher
  • Process for preparing spiro[2.5]octane-5,7-dione
    Publication number: 20140336405
    Abstract: Disclosed is a method for the synthesis of spiro[2.5]octane-5,7-dione useful as intermediate in the manufacture of pharmaceutically active ingredients. Also disclosed are novel intermediates used in the synthesis of this compound.
    Type: Application
    Filed: July 29, 2014
    Publication date: November 13, 2014
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Torsten BUSCH, Sven ANKLAM, Joerg JUNG, Markus OSTERMEIER
  • PROCESS FOR THE PREPARATION OF BORONIC ACID INTERMEDIATES
    Publication number: 20140330008
    Abstract: The present invention relates to a process for the preparation of 2-amino-pyrimidine-5-boronic acid of formula (I). or salts or esters thereof.
    Type: Application
    Filed: May 5, 2014
    Publication date: November 6, 2014
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Torsten Busch, Michael Nonnenmacher
  • Process for preparing spiro[2.5]octane-5,7-dione
    Publication number: 20140039203
    Abstract: Disclosed is a method for the synthesis of spiro[2.5]octane-5,7-dione useful as intermediate in the manufacture of pharmaceutically active ingredients. Also disclosed are novel intermediates used in the synthesis of this compound.
    Type: Application
    Filed: August 1, 2013
    Publication date: February 6, 2014
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Torsten BUSCH, Sven ANKLAM, Joerg JUNG, Markus OSTERMEIER