Patents by Inventor Torsten Ertongur-Fauth

Torsten Ertongur-Fauth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENRICHMENT OF GENOME-EDITED CELLS
    Publication number: 20210163937
    Abstract: The present invention relates to a method for enriching cells within a cell population, wherein a gene of interest is genome edited, said method comprising (a) introducing into the cells within the cell population one or more nucleic acid molecules, said one or more nucleic acid molecules encoding in expressible form (i) a CRISPR nuclease, (ii) a guide RNA for knocking-out the leucine-rich repeat-containing protein 8 A (LRRC8A), LRRC8B, LRRC8C, LRRC8D or LRRC8E gene or a guide RNA for knocking-out an innexin gene, and (iii) a guide RNA for editing the gene of interest; or (a?) introducing into the cells within the cell population (i) a CRISPR nuclease, and one or more nucleic acid molecules, said one or more nucleic acid molecules encoding in expressible form (ii) a guide RNA for knocking-out the leucine-rich repeat-containing protein 8 A (LRRC8A), LRRC8B, LRRC8C, LRRC8D or LRRC8E gene or a guide RNA for knocking-out an innexin gene, and (iii) a guide RNA for editing the gene of interest; or (a?) introducting
    Type: Application
    Filed: April 18, 2019
    Publication date: June 3, 2021
    Inventors: Ümit PUL, Torsten ERTONGUR-FAUTH, Sophia GRÜNER, Janina TROTHE
  • Compositions and methods for reducing cat allergens in the environment
    Patent number: 10889785
    Abstract: Formulations, compositions and products for reducing allergenic Fel d 1 from the environment are disclosed. The formulations include at least one protease that interacts with the Fel d 1 and substantially degrades allergenic epitopes on the Fel d 1. Methods of using the formulations for reducing or eliminating allergenic Fel d 1 from the environment are also disclosed.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: January 12, 2021
    Assignee: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
    Inventors: George Wells, Delphine Tissot-Favre, Ebenezer Satyaraj, Juergen Eck, Daniel Meyer, Torsten Ertongur-Fauth, Alexander Pelzer, Scott Sherrill, Peichuan Sun
  • THE VOLUME-REGULATED ANION CHANNEL PROTEIN LRRC8A FOR USE IN ALTERING EPIDERMAL KERATINOCYTE DIFFERENTIATION
    Publication number: 20200393448
    Abstract: The present invention relates to the leucine-rich repeat-containing protein 8A (LRRC8A), and/or an activator of LRRC8A, for use in the treatment and/or prevention of a skin condition associated with an altered differentiation of keratinocytes. Preferably, the skin condition associated with an altered differentiation of keratinocytes is psoriasis or dermatitis, preferably atopic dermatitis.
    Type: Application
    Filed: February 15, 2019
    Publication date: December 17, 2020
    Inventors: Torsten ERTONGUR-FAUTH, Janina TROTHE, Claudia BÜRGER
  • COMPOSITIONS AND METHODS FOR REDUCING CAT ALLERGENS IN THE ENVIRONMENT
    Publication number: 20180223223
    Abstract: Formulations, compositions and products for reducing allergenic Fel d 1 from the environment are disclosed. The formulations include at least one protease that interacts with the Fel d 1 and substantially degrades allergenic epitopes on the Fel d 1. Methods of using the formulations for reducing or eliminating allergenic Fel d 1 from the environment are also disclosed.
    Type: Application
    Filed: April 4, 2018
    Publication date: August 9, 2018
    Inventors: George Wells, Delphine Tissot-Favre, Ebenezer Satyaraj, Juergen Eck, Daniel Meyer, Torsten Ertongur-Fauth, Alexander Pelzer, Scott Sherrill, Peichuan Sun
  • Calcium-activated chloride channel involved in human sweat formation
    Patent number: 9809853
    Abstract: Accordingly, the present invention relates to a nucleic acid molecule encoding a protein capable of forming a calcium-activated chloride channel, wherein said nucleic acid molecule comprises or consists of (a) a nucleic acid molecule encoding a protein having the amino acid sequence of SEQ ID NO:1; (b) a nucleic acid molecule having the DNA sequence of SEQ ID NO:2; (c) a nucleic acid molecule having the sequence of SEQ ID NO:2, wherein each thymine is replaced by uracil; (d) a nucleic acid molecule that hybridizes under stringent conditions to the complementary strand of a nucleic acid molecule of (a), (b) or (c); (e) a nucleic acid molecule encoding a protein having at least 97% sequence identity to the protein of (a); or (f) a nucleic acid molecule that is degenerate with respect to the nucleic acid molecule of (b), (c) or (d).
    Type: Grant
    Filed: August 14, 2013
    Date of Patent: November 7, 2017
    Assignee: Brain Biotechnology Research and Information Network AG
    Inventors: Torsten Ertongur-Fauth, Andreas Hochheimer, Michael Krohn
  • NOVEL CALCIUM-ACTIVATED CHLORIDE CHANNEL INVOLVED IN HUMAN SWEAT FORMATION
    Publication number: 20150240303
    Abstract: Accordingly, the present invention relates to a nucleic acid molecule encoding a protein capable of forming a calcium-activated chloride channel, wherein said nucleic acid molecule comprises or consists of (a) a nucleic acid molecule encoding a protein having the amino acid sequence of SEQ ID NO:1; (b) a nucleic acid molecule having the DNA sequence of SEQ ID NO:2; (c) a nucleic acid molecule having the sequence of SEQ ID NO:2, wherein each thymine is replaced by uracil; (d) a nucleic acid molecule that hybridizes under stringent conditions to the complementary strand of a nucleic acid molecule of (a), (b) or (c); (e) a nucleic acid molecule encoding a protein having at least 97% sequence identity to the protein of (a); or (f) a nucleic acid molecule that is degenerate with respect to the nucleic acid molecule of (b), (c) or (d).
    Type: Application
    Filed: August 14, 2013
    Publication date: August 27, 2015
    Inventors: Torsten Ertongur-Fauth, Andreas Hochheimer, Michael Krohn
  • COMPOSITIONS AND METHODS FOR REDUCING CAT ALLERGENS IN THE ENVIRONMENT
    Publication number: 20150175940
    Abstract: Formulations, compositions and products for reducing allergenic Fel d 1 from the environment are disclosed. The formulations include at least one protease that interacts with the Fel d 1 and substantially degrades allergenic epitopes on the Fel d 1. Methods of using the formulations for reducing or eliminating allergenic Fel d 1 from the environment are also disclosed.
    Type: Application
    Filed: December 15, 2014
    Publication date: June 25, 2015
    Inventors: George Wells, Delphine Tissot-Favre, Ebenezer Satyaraj, Juergen Eck, Daniel Meyer, Torsten Ertongur-Fauth, Alexander Pelzer, Scott Sherrill, Peichuan Sun