Patents by Inventor Torsten Minuth

Torsten Minuth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PURIFICATION OF INTERLEUKIN-4 AND ITS MUTEINS
    Publication number: 20110060128
    Abstract: This invention relates generally to a method for purifying Interleukin-4 or related variants from an Escherichia coli culture medium, where Interleukin-4 and its derivatives are expressed as insoluble protein aggregates, so-called inclusion bodies.
    Type: Application
    Filed: November 12, 2010
    Publication date: March 10, 2011
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Jörg Peters, Torsten Minuth, Hans-Georg Dellweg
  • Process for renaturation of recombinant, disulfide containing proteins at high protein concentrations in the presence of amines
    Patent number: 7893210
    Abstract: A method for renaturation of proteins comprising adding to a solution of denatured, chemically modified or reduced proteins a refolding buffer containing a primary, secondary or tertiary amine. Said method has been applied, for example, to interleukin-4 and bovine pancreatic trypsin inhibitor (BPTI), which were previously (i) solubilized in the presence of guanidinium hydrochloride as chaotronic agent, and (ii) subjected to sulfitolysis.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: February 22, 2011
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Jörg Peters, Torsten Minuth
  • Method for preparing viral material
    Patent number: 7666654
    Abstract: The invention relates to a method for preparing viral suspensions. The invention relates in particular to a method for preparing high-titer viral suspensions in cell cultures. Preferred methods include increasing the volume of the cell culture prior to infection with viral material and subsequent further steps of expanding the volume to a final volume which is distinctly larger than the maximum culture volume prior to infection.
    Type: Grant
    Filed: April 5, 2007
    Date of Patent: February 23, 2010
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Michael Pohlscheidt, Berthold Boedeker, Torsten Minuth, Heiner Apeler, Uwe Langer, Katrin Brabender, Dirk Otto-Brabender, Joachim Kerper, Hans-Juergen Henzler
  • Method for preparing viral material
    Publication number: 20080014626
    Abstract: The invention relates to a method for preparing viral suspensions. The invention relates in particular to a method for preparing high-titer viral suspensions in cell cultures. Preferred methods include increasing the volume of the cell culture prior to infection with viral material and subsequent further steps of expanding the volume to a final volume which is distinctly larger than the maximum culture volume prior to infection.
    Type: Application
    Filed: April 5, 2007
    Publication date: January 17, 2008
    Inventors: Michael Pohlscheidt, Berthold Boedeker, Torsten Minuth, Heiner Apeler, Uwe Langer, Katrin Brabender, Dirk Otto-Brabender, Joachim Kerper, Hans-Juergen Henzler
  • Process for the purification of interleukin-4 and its muteins
    Publication number: 20060134690
    Abstract: This invention relates generally to a method for purifying Interleukin-4 or related variants from an Escherichia coli culture medium, where Interleukin-4 and its derivatives are expressed as insoluble protein aggregates, so-called inclusion bodies.
    Type: Application
    Filed: July 2, 2003
    Publication date: June 22, 2006
    Inventors: Jorg Peters, Torsten Minuth, Hans-Georg Dellweg
  • Process for renaturation of recombinant, disulfide containing proteins at high protein concentrations in the presence of amines
    Publication number: 20050014933
    Abstract: A method for renaturation of proteins comprising adding to a solution of denatured, chemically modified or reduced proteins a refolding buffer containing a primary, secondary or tertiary amine. Said method has been applied, for example, to interleukin-4 and bovine pancreatic trypsin inhibitor (BPTI), wich were previously (i) solubilized in the presence of guanidinium hydrochloride as chaotronic agent, and (ii) subjected to sulfitolysis.
    Type: Application
    Filed: November 12, 2002
    Publication date: January 20, 2005
    Inventors: Jörg Peters, Torsten Minuth