Patents by Inventor Torsten Stelzer

Torsten Stelzer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients
    Patent number: 12643083
    Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
    Type: Grant
    Filed: December 21, 2022
    Date of Patent: June 2, 2026
    Assignee: Massachusetts Institute of Technology
    Inventors: Klavs F. Jensen, Timothy F. Jamison, Allan Stuart Myerson, Jean-Christophe M. Monbaliu, Mohsen Behnam, Shin Yee Wong, Nopphon Weeranoppanant, Eve Marie Revalor, Torsten Stelzer, Jie Chen, Andrea Adamo, David R. Snead, Ping Zhang
  • CRYSTALLINE FORMS OF CARBAZOLE INHIBITORS OF RhoGTPase FOR THE TREATMENT OF DISEASE
    Publication number: 20250230145
    Abstract: Disclosed herein are crystalline forms of compounds for the inhibition of RhoGTPase. Also disclosed herein are compounds, pharmaceutical compositions, and methods of treatment of RhoGTPase-mediated diseases, such as hyperproliferative and neoplastic diseases.
    Type: Application
    Filed: December 19, 2024
    Publication date: July 17, 2025
    Inventors: Jocelyn M. JIMÉNEZ CRUZ, Vilmalí LÓPEZ-MEJÍAS, Torsten STELZER
  • Crystalline forms of carbazole inhibitors of RhoGTPase for the treatment of disease
    Patent number: 12209078
    Abstract: Disclosed herein are crystalline forms of compounds for the inhibition of RhoGTPase. Also disclosed herein are compounds, pharmaceutical compositions, and methods of treatment of RhoGTPase-mediated diseases, such as hyperproliferative and neoplastic diseases.
    Type: Grant
    Filed: October 5, 2022
    Date of Patent: January 28, 2025
    Assignee: MBQ Pharma
    Inventors: Jocelyn M. Jiménez Cruz, Vilmalí López-Mejías, Torsten Stelzer
  • CRYSTALLINE FORMS OF CARBAZOLE INHIBITORS OF RhoGTPase FOR THE TREATMENT OF DISEASE
    Publication number: 20230303529
    Abstract: Disclosed herein are crystalline forms of compounds for the inhibition of RhoGTPase. Also disclosed herein are compounds, pharmaceutical compositions, and methods of treatment of RhoGTPase-mediated diseases, such as hyperproliferative and neoplastic diseases.
    Type: Application
    Filed: October 5, 2022
    Publication date: September 28, 2023
    Inventors: Jocelyn M. JIMÉNEZ CRUZ, Vilmalí LÓPEZ-MEJÍAS, Torsten STELZER
  • SYSTEMS AND METHODS FOR SYNTHESIZING CHEMICAL PRODUCTS, INCLUDING ACTIVE PHARMACEUTICAL INGREDIENTS
    Publication number: 20230201787
    Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
    Type: Application
    Filed: December 21, 2022
    Publication date: June 29, 2023
    Applicant: Massachusetts Institute of Technology
    Inventors: Klavs F. Jensen, Timothy F. Jamison, Allan Stuart Myerson, Jean-Christophe M. Monbaliu, Mohsen Behnam, Shin Yee Wong, Nopphon Weeranoppanant, Eve Marie Revalor, Torsten Stelzer, Jie Chen, Andrea Adamo, David R. Snead, Ping Zhang
  • Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients
    Patent number: 11565230
    Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: January 31, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Klavs F. Jensen, Timothy F. Jamison, Allan S. Myerson, Jean-Christophe M. Monbaliu, Mohsen Behnam, Shin Yee Wong, Nopphon Weeranoppanant, Eve Marie Revalor, Torsten Stelzer, Jie Chen, Andrea Adamo, David R. Snead, Ping Zhang
  • SYSTEMS AND METHODS FOR SYNTHESIZING CHEMICAL PRODUCTS, INCLUDING ACTIVE PHARMACEUTICAL INGREDIENTS
    Publication number: 20200368710
    Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
    Type: Application
    Filed: August 10, 2020
    Publication date: November 26, 2020
    Applicant: Massachusetts Institute of Technology
    Inventors: Klavs F. Jensen, Timothy F. Jamison, Allan S. Myerson, Jean-Christophe M. Monbaliu, Mohsen Behnam, Shin Yee Wong, Nopphon Weeranoppanant, Eve Marie Revalor, Torsten Stelzer, Jie Chen, Andrea Adamo, David R. Snead, Ping Zhang
  • Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients
    Patent number: 10780410
    Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: September 22, 2020
    Assignee: Massachusetts Institute of Technology
    Inventors: Klavs F. Jensen, Timothy F. Jamison, Allan S. Myerson, Jean-Christophe M. Monbaliu, Mohsen Behnam, Shin Yee Wong, Nopphon Weeranoppanant, Eve Marie Revalor, Torsten Stelzer, Jie Chen, Andrea Adamo, David R. Snead, Ping Zhang
  • Pressure driven flow crystallizer
    Patent number: 10155786
    Abstract: The present invention generally relates to systems and methods for pressure driven flow crystallization. In some embodiments, the system comprises a comprising a cavity and a mixing mechanism. In some embodiments, one or more inlets facilitate the transfer of one or more reagent streams to the cavity. In some such embodiments, the mixing mechanism mixes the first and second reagent streams such that a continuous crystallization and/or generation of a product (e.g., solid particles) in the fluid.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: December 18, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: Allan S. Myerson, Marcus O'Mahony, Torsten Stelzer, Yuqing Cui
  • Pressure driven flow crystallizer
    Publication number: 20170166601
    Abstract: The present invention generally relates to systems and methods for pressure driven flow crystallization. In some embodiments, the system comprises a comprising a cavity and a mixing mechanism. In some embodiments, one or more inlets facilitate the transfer of one or more reagent streams to the cavity. In some such embodiments, the mixing mechanism mixes the first and second reagent streams such that a continuous crystallization and/or generation of a product (e.g., solid particles) in the fluid.
    Type: Application
    Filed: December 8, 2016
    Publication date: June 15, 2017
    Applicant: Massachusetts Institute of Technology
    Inventors: Allan S. Myerson, Marcus O'Mahony, Torsten Stelzer, Yuqing Cui