Abstract: A hemostatic material includes a lipid that can accelerate adhesion or aggregation of platelets even if the lipid does not carry a protein or a peptide involved in adhesion or aggregation of platelets such as GPIb and H12 and, to achieve the object, provides a hemostatic material including a water-insoluble base and a lipid supported on a surface of the base, wherein the lipid includes one or two or more anionic lipids.

Abstract: A filter having a plurality of filter pores penetrating one surface and another surface of the filter, wherein the filter pore has a first opening on the one surface and a second opening on the another surface, a ratio (L1/W1) of a major axis diameter L1 to a minor axis diameter W1 of the first opening is 1.00 or more and 1.20 or less, the minor axis diameter W1 is 7.0 ?m or more and 9.0 ?m or less, a ratio (L2/W2) of a major axis diameter L2 to a minor axis diameter W2 of the second opening is 1.00 or more and 1.20 or less, and a ratio (W2/W1) of the minor axis diameter W2 to the minor axis diameter W1 and a ratio (L2/L1) of the major axis diameter L2 to the major axis diameter L1 are both 1.20 or more and 1.50 or less.

Abstract: A hemostatic material includes a lipid that can accelerate adhesion or aggregation of platelets even if the lipid does not carry a protein or a peptide involved in adhesion or aggregation of platelets such as GPIb and H12 and, to achieve the object, provides a hemostatic material including a water-insoluble base and a lipid supported on a surface of the base, wherein the lipid includes one or two or more anionic lipids.

Abstract: A carboxylic acid-type lipid can accelerate adhesion or aggregation of platelets even if the carboxylic acid-type lipid does not carry a protein involved in adhesion or aggregation of platelets or a peptide corresponding to an active site of the protein; a lipid particle and a lipid membrane each include the carboxylic acid-type lipid; and a platelet aggregation accelerating agent, a platelet adhesion accelerating agent, a hemostatic agent and a platelet substitute each include the carboxylic acid-type lipid, the lipid particle or the lipid membrane. A carboxylic acid-type lipid is selected from carboxylic acid-type lipids represented by formulas (I) to (VI), a lipid particle includes the carboxylic acid-type lipid, a lipid membrane includes the carboxylic acid-type lipid, and a platelet aggregation accelerating agent, a platelet adhesion accelerating agent, a hemostatic agent and a platelet substitute each include the carboxylic acid-type lipid, the lipid particle or the lipid membrane.

Abstract: A material for adhesion prevention can be adhered to biological tissue with certainty and has improved tissue adhesiveness and biodegradability. Such material for adhesion prevention is composed of: a 1- to 1,000-?m-thick water-soluble support layer comprising a water-soluble polymer; and a 1- to 1,000-?m-thick adhesion prevention layer comprising a biodegradable polymer. The biodegradable polymer has a structure in which a branched polyalkylene glycol comprising 3 to 8 terminal hydroxyl groups per molecule is bound to a polyhydroxy alkanoic acid, and a mass ratio of the branched polyalkylene glycol relative to the total mass is 1% to 30%.

Abstract: A wearable electrode includes: a garment including an outer member and a backing member configured to cover at least a part of an inner surface of the outer member; and an electrode unit configured to come into contact with a living body clothed in the garment to acquire a biological signal emitted by the living body and attached to an opposite side of the backing member from the outer member. The outer member and the backing member are connected to each other in a part other than a part of the backing member, to which the electrode unit is attached.

Abstract: A wearable electrode includes: a garment including an outer member and a backing member configured to cover at least a part of an inner surface of the outer member; and an electrode unit configured to come into contact with a living body clothed in the garment to acquire a biological signal emitted by the living body and attached to an opposite side of the backing member from the outer member, and a core wire which can be inserted into an accommodation section formed in the electrode unit. The outer member and the backing member are connected to a part other than a part of the backing member, to which the electrode unit is attached.

Abstract: A laminate has at least one polylactic acid resin-containing layer (C) with a thickness of 10-500 nm on at least one surface of a fibrous structure (B) containing a water-soluble resin (A). A production method for the laminate is characterized in that water or an aqueous solution is applied to the joining surface of the fibrous structure (B) and the polylactic acid resin-containing layer (C). The laminate exhibits excellent followability, adherence and coatability relative to flexible, curved adherends, exhibits excellent compatibility to organs such as skin and internal organs, and, because the fibrous structure (B) containing a water-soluble resin (A) can easily be removed from the polylactic acid resin-containing layer (C) by the aqueous solution, is adapted for use in materials for external use on the skin, such as wound-dressing materials, adhesion-preventing materials, and skin care products.

Abstract: A multilayer sheet can be used in vivo or in an environment in which moisture is adhered, an integrated sheet including the multilayer sheet and a base material, and methods for producing the same. The multilayer sheet has one or more layers from each of a layer (A) composed of sparingly water-soluble polymer and a fiber layer (B) composed of water-soluble polymer are laminated, and at least one of outermost layers is the above-described layer (A) composed of sparingly water-soluble polymer. The time taken from dropping of water onto a surface of the outermost layer of the above-described layer (A) composed of sparingly water-soluble polymer to dissolution of the other outermost layer is 10 seconds to 5 minutes.

Abstract: A biomedical electrode which is detachably attached to a garment and includes: an electrode coming into contact with a living body clothed in the garment to acquire a biological signal emitted by the living body; and a locked section which is conductive, is electrically connected to the electrode, is detachably locked to a locking section which is conductive and is provided in the garment, and is electrically connected to the locking section when locked to the locking section.

Abstract: A biomedical electrode which is detachably attached to a garment and includes: an electrode coming into contact with a living body clothed in the garment to acquire a biological signal emitted by the living body; and a locked section which is conductive, is electrically connected to the electrode, is detachably locked to a locking section which is conductive and is provided in the garment, and is electrically connected to the locking section when locked to the locking section.

Abstract: A polymer film has an average film thickness T0 along a straight line D passing through the center of gravity of a two-dimensional projection such that the area of the polymer film is maximized, satisfies equation (a), the average value L of distances 1 from the center of gravity to edges satisfies equation (b), the Young's modulus E satisfies equation (c), and the thickness deviation ? defined by equation (d) satisfies equation (e); and a dispersion liquid and an agglomerate using the same. (a) 10 nm?T0?1000 nm, (b) 0.1 ?m?L?500 ?m, (c) 0.01 GPa?E?4.3 GPa, (d) ?=1?T1/T2, (e) 0.346E×10?9?1.499<?<?0.073E×10?9+0.316.

Abstract: A polymer laminate has 2-100 layers each containing a biodegradable resin and having a thickness of 10 nm-400 nm that are laminated, the thickness of at least one of the outermost layers is 10 nm-180 nm, and the outermost layers are joined to each other. A polymer laminate excellent in biocompatibility and mechanical strength and suitable to medical applications such as wound dressings and antiadhesive materials can be obtained.

Abstract: A material for adhesion prevention can be adhered to biological tissue with certainty and has improved tissue adhesiveness and biodegradability. Such material for adhesion prevention is composed of: a 1- to 1,000-?m-thick water-soluble support layer comprising a water-soluble polymer; and a 1- to 1,000-?m-thick adhesion prevention layer comprising a biodegradable polymer. The biodegradable polymer has a structure in which a branched polyalkylene glycol comprising 3 to 8 terminal hydroxyl groups per molecule is bound to a polyhydroxy alkanoic acid, and a mass ratio of the branched polyalkylene glycol relative to the total mass is 1% to 30%.

Abstract: A polymer film can be adjusted to movement or a fine uneven surface of a living body and has excellent ability to adhere to a biological tissue. The polymer film includes a block copolymer having a structure in which branched polyalkylene glycol and polyhydroxyalkanoic acid are bound to each other, wherein the polymer film has a film thickness of 10 to 1000 nm. The branched polyalkylene glycol has at least three terminal hydroxyl groups per molecule, the mass percentage of the branched polyalkylene glycol relative to the total mass of the block copolymer is 1% to 30%, and a value obtained by dividing the average molecular weight of polyhydroxyalkanoic acid in the block copolymer by X that is the number of terminal hydroxyl groups present per a single molecule of the branched polyalkylene glycol is 10000 to 30000.

Abstract: A polymer film has an average film thickness T0 along a straight line D passing through the center of gravity of a two-dimensional projection such that the area of the polymer film is maximized, satisfies equation (a), the average value L of distances 1 from the center of gravity to edges satisfies equation (b), the Young's modulus E satisfies equation (c), and the thickness deviation ? defined by equation (d) satisfies equation (e); and a dispersion liquid and an agglomerate using the same. (a) 10 nm?T0?1000 nm, (b) 0.1 ?m?L?500 ?m, (c) 0.01 GPa?E?4.3 GPa, (d) ?=1?T1/T2, (e) 0.346E×10?9?1.499<?<?0.073E×10?9+0.316.

Abstract: A polymer film can be adjusted to movement or a fine uneven surface of a living body and has excellent ability to adhere to a biological tissue. The polymer film includes a block copolymer having a structure in which branched polyalkylene glycol and polyhydroxyalkanoic acid are bound to each other, wherein the polymer film has a film thickness of 10 to 1000 nm. The branched polyalkylene glycol has at least three terminal hydroxyl groups per molecule, the mass percentage of the branched polyalkylene glycol relative to the total mass of the block copolymer is 1% to 30%, and a value obtained by dividing the average molecular weight of polyhydroxyalkanoic acid in the block copolymer by X that is the number of terminal hydroxyl groups present per a single molecule of the branched polyalkylene glycol is 10000 to 30000.

Abstract: A multilayer sheet can be used in vivo or in an environment in which moisture is adhered, an integrated sheet including the multilayer sheet and a base material, and methods for producing the same. The multilayer sheet has one or more layers from each of a layer (A) composed of sparingly water-soluble polymer and a fiber layer (B) composed of water-soluble polymer are laminated, and at least one of outermost layers is the above-described layer (A) composed of sparingly water-soluble polymer. The time taken from dropping of water onto a surface of the outermost layer of the above-described layer (A) composed of sparingly water-soluble polymer to dissolution of the other outermost layer is 10 seconds to 5 minutes.

Abstract: A polymer laminate has 2-100 layers each containing a biodegradable resin and having a thickness of 10 nm-400 nm that are laminated, the thickness of at least one of the outermost layers is 10 nm-180 nm, and the outermost layers are joined to each other. A polymer laminate excellent in biocompatibility and mechanical strength and suitable to medical applications such as wound dressings and antiadhesive materials can be obtained.