Abstract: An endoscope system performs image processing using a G1 image data (image data obtained by irradiating light of 524±3 nm to 582±3 nm) and at least one of R1 image (image data obtained by irradiating light of 630±3 nm to 700±3 nm) data other than the G1 image data, B1 image data (452±3 nm to 502±3 nm), R2 image data (image data obtained by irradiating light of 582±3 nm to 630±3 nm), G2 image data (image data obtained by irradiating light of 502±3 nm to 524±3 nm), and B2 image data (image data obtained by irradiating light of 420±3 nm to 452±3 nm) so as to generate a special light image (FIG. 7).

Abstract: Provided is a technology capable of generating and presenting more kinds of special light images with higher image quality. An endoscope system according to the present disclosure performs image processing using a G1 image data (image data obtained by irradiating light of 524±3 nm to 582±3 nm) and at least one of R1 image (image data obtained by irradiating light of 630±3 nm to 700±3 nm) data other than the G1 image data, B1 image data (452±3 nm to 502±3 nm), R2 image data (image data obtained by irradiating light of 582±3 nm to 630±3 nm), G2 image data (image data obtained by irradiating light of 502±3 nm to 524±3 nm), and B2 image data (image data obtained by irradiating light of 420±3 nm to 452±3 nm) so as to generate a special light image (FIG. 7).

Abstract: An endoscope system includes: a processor that generates first and second feature amount distribution images of a living tissue from an imaged image of the living tissue and generates a second feature amount distribution processed image from these distribution images; and a display that displays the second feature amount distribution processed image. The processor generates a mask image of the second feature amount distribution image by, in the first feature amount distribution image, setting a pixel whose pixel value representing the first feature amount is less than a lower limit value as a non-transmissive pixel having a transmittance of zero and setting a pixel between an upper limit value and the lower limit value as a transmissive pixel while giving the pixel a transmittance determined continuously or stepwise in accordance with the pixel value in the first feature amount distribution image.

Abstract: An endoscope system includes an endoscope with an image pickup that generates image data by capturing an image of tissue illuminated with light containing wavelength regions spaced from and not overlapping with each other. The image pickup has an RGB filter, the wavelength regions include first and second regions corresponding to a B region and to a G region of the filter. A processor calculates an index representing a molar concentration ratio of first and second biological substances contained in the tissue based on the image data including information on the first and second regions. In the first region, image data B of the tissue varies depending on the molar concentration ratio, the second region contains isosbestic points of the tissue, and, in the second region, image data G has a constant value. The processor calculates the index based on the data B and G.

Abstract: Provided is a technology capable of generating and presenting more kinds of special light images with higher image quality. An endoscope system according to the present disclosure performs image processing using a G1 image data (image data obtained by irradiating light of 524±3 nm to 582±3 nm) and at least one of R1 image (image data obtained by irradiating light of 630±3 nm to 700±3 nm) data other than the G1 image data, B1 image data (452±3 nm to 502±3 nm), R2 image data (image data obtained by irradiating light of 582±3 nm to 630±3 nm), G2 image data (image data obtained by irradiating light of 502±3 nm to 524±3 nm), and B2 image data (image data obtained by irradiating light of 420±3 nm to 452±3 nm) so as to generate a special light image (FIG. 7).

Abstract: An endoscope apparatus according to an embodiment of the present invention includes: a light source apparatus; an imager that has an image sensor and generates color image data by imaging biological tissue illuminated by light emitted by the light source apparatus; and a feature amount acquisitioner that acquires a feature amount of the biological tissue based on the color image data. The feature amount acquisitioner includes: a first parameter generator that, based on the color image data, generates a first parameter that has sensitivity to a first feature amount of the biological tissue, but substantially does not have sensitivity to light scattering by the biological tissue; and a first feature amount acquisitioner that acquires the first feature amount based on the first parameter.

Abstract: An endoscope system includes a processor and displays a distribution image of living substance feature amounts obtained from an imaged image of a living tissue. The processor calculates the living substance feature amount in the living tissue, for example, an amount of hemoglobin and oxygen saturation of the hemoglobin using components of color image data of the living tissue illuminated with at least two lights, generates the feature amount distribution image illustrating a distribution of the living substance feature amounts, and controls display of the feature amount distribution image in order to display the generated feature amount distribution image so as to be superimposed on the image of the living tissue.

Abstract: An analysis device includes a wavelength selection unit that alternatively extracts first special light and second special light from light emitted from the light source device, an image sensor that includes a RGB color filter, and a signal processing unit. In this configuration, the first special light includes light in a first wavelength region and the second special light includes light in a second wavelength region that is different from the first wavelength region. The signal processing unit calculates an indicator that indicates a feature amount of biological tissue based on a pixel signal that corresponds to the light in the first wavelength region and a pixel signal that corresponds to the light in the second wavelength region, and generates a color captured image based on a pixel signal that corresponds to light that passes through the RGB color filter.

Abstract: Generating an image of a molar concentration ratio between a first and second biological substance, an absorption spectrum of the first and second biological substance within a predetermined wavelength range including a first, second, third, and fourth isosbestic point, acquiring first imaging data of the tissue using light extracted from white light using a first filter to collectively selectively extract light in a first wavelength range demarcated by the first and second isosbestic point, light in a second wavelength range demarcated by the second and third isosbestic point, and light in a third wavelength range demarcated by the third and fourth isosbestic point; acquiring second imaging data by taking an image of the tissue using light from the white light using a second optical filter to selectively extract light in the second wavelength range; and generating the distribution image on the basis of the first and second imaging data.

Abstract: An endoscope system includes an endoscope with an image pickup that generates image data by capturing an image of tissue illuminated with light containing wavelength regions spaced from and not overlapping with each other. The image pickup has an RGB filter, the wavelength regions include first and second regions corresponding to a B region and to a G region of the filter. A processor calculates an index representing a molar concentration ratio of first and second biological substances contained in the tissue based on the image data including information on the first and second regions. In the first region, image data B of the tissue varies depending on the molar concentration ratio, the second region contains isosbestic points of the tissue, and, in the second region, image data G has a constant value. The processor calculates the index based on the data B and G.

Abstract: An endoscope system includes: a processor that generates first and second feature amount distribution images of a living tissue from an imaged image of the living tissue and generates a second feature amount distribution processed image from these distribution images; and a display that displays the second feature amount distribution processed image. The processor generates a mask image of the second feature amount distribution image by, in the first feature amount distribution image, setting a pixel whose pixel value representing the first feature amount is less than a lower limit value as a non-transmissive pixel having a transmittance of zero and setting a pixel between an upper limit value and the lower limit value as a transmissive pixel while giving the pixel a transmittance determined continuously or stepwise in accordance with the pixel value in the first feature amount distribution image.

Abstract: A solid sample to be used as a calibration reference sample to calculate a hemoglobin concentration and a hemoglobin oxygen saturation in a living tissue is made of non-biological substance having: a colorant group that has a plurality of colorants of non-biological substances and reproduces absorption characteristics of the hemoglobin with a predetermined concentration and a predetermined oxygen saturation by adjusting a mixing ratio of the plurality of colorants; and a resin material in which each colorant of the colorant group is dispersed. In preparing the solid sample, the colorant group reproducing the hemoglobin absorption characteristics with the predetermined hemoglobin concentration and the predetermined hemoglobin oxygen saturation is prepared, and then, resin as a base material is dissolved in a mixed solution in which the colorant group is dispersed in an organic solvent. The organic solvent is volatilized from the mixed solution in which the resin has been dissolved.

Abstract: An image capturing system, comprising: a light source device that emits illumination light containing wavelength regions; an image pickup device having an RGB filter; and an image processing unit to calculate a first index representing a molar concentration ratio of a first biological substance and a second biological substance contained in the living tissue, wherein the wavelength regions comprise: a first wavelength region corresponding to a B filter; and a second wavelength region corresponding to a G filter, wherein: in the first wavelength region, a value of image data B varies depending on the molar concentration ratio; the second wavelength region contains a plurality of isosbestic points of the living tissue, and, in the second wavelength region, a value of image data G takes a constant value without depending on the molar concentration ratio.

Abstract: An analyzing apparatus according to an embodiment of the present invention includes: a light source apparatus; an image sensor that generates color image data by capturing an image of biological tissue illuminated by light generated by the light source apparatus; an indicator calculation unit that calculates an indicator X that indicates a feature amount Q of the biological tissue, based on the color image data; and a feature amount acquisition unit that acquires the feature amount Q based on the indicator X. The feature amount acquisition unit includes a contribution calculation unit that calculates a contribution C based on at least two colors of single-color image data included in the color image data, the contribution C of scattering on a spectral characteristic of the biological tissue. Also, the feature amount acquisition unit acquires the feature amount Q based on the indicator X and the contribution C.

Abstract: An endoscope system includes a processor and displays a distribution image of living substance feature amounts obtained from an imaged image of a living tissue. The processor calculates the living substance feature amount in the living tissue, for example, an amount of hemoglobin and oxygen saturation of the hemoglobin using components of color image data of the living tissue illuminated with at least two lights, generates the feature amount distribution image illustrating a distribution of the living substance feature amounts, and controls display of the feature amount distribution image in order to display the generated feature amount distribution image so as to be superimposed on the image of the living tissue.

Abstract: An analysis device includes a wavelength selection unit that alternatively extracts first special light and second special light from light emitted from the light source device, an image sensor that includes a RGB color filter, and a signal processing unit. In this configuration, the first special light includes light in a first wavelength region and the second special light includes light in a second wavelength region that is different from the first wavelength region. The signal processing unit calculates an indicator that indicates a feature amount of biological tissue based on a pixel signal that corresponds to the light in the first wavelength region and a pixel signal that corresponds to the light in the second wavelength region, and generates a color captured image based on a pixel signal that corresponds to light that passes through the RGB color filter.

Abstract: A calculation system is constituted by: one light source apparatus configured to irradiate illuminating light; a wavelength selection unit configured to select light of at least two specific wavelength regions included in the illuminating light; an image sensor configured to receive light from biological tissue, which is a subject, and output pixel signals corresponding to the received light; and a signal processing unit configured to perform predetermined signal processing on the pixel signals output from the image sensor. In this configuration, the signal processing unit calculates an index indicating a concentration of a predetermined biological substance included in the biological tissue, based on the pixel signals output from the image sensor according to the light of the at least two specific wavelength regions.

Abstract: The present invention relates to the development of a stomatological composition and a kit each comprising an NSAID such as ibuprofen, a heparin compound, or a pharmaceutically acceptable salt thereof for the prevention, alleviation, or treatment of inflammations associated with oral cavity diseases and/or pains/infections associated with the inflammations and of inflammatory pain diseases/infections of the pharynx and/or the esophagus, and to a method for producing the composition and a method of use of the composition for the production of a medicament.

Abstract: An analyzing device, comprising: a light source device; an image pick-up device that generates image data by capturing a biological tissue illuminated with light emitted by the light source device; and an index calculation unit configured to calculate an index representing a molar ratio between first and second biological substances contained in the biological tissue based on the image data, wherein: the light source device switches between light of a first illumination wavelength range which the first and second biological substances absorb and light of a second illumination wavelength range lying within the first illumination wavelength range; and the index calculation unit calculates the index based on first image data obtained by capturing the biological tissue under illumination of the light of the first illumination wavelength range and second image data obtained by capturing the biological tissue under illumination of the light of the second illumination wavelength range.

Abstract: An analyzing apparatus according to an embodiment of the present invention includes: a light source apparatus; an image sensor that generates color image data by capturing an image of biological tissue illuminated by light generated by the light source apparatus; an indicator calculation unit that calculates an indicator X that indicates a feature amount Q of the biological tissue, based on the color image data; and a feature amount acquisition unit that acquires the feature amount Q based on the indicator X. The feature amount acquisition unit includes a contribution calculation unit that calculates a contribution C based on at least two colors of single-color image data included in the color image data, the contribution C of scattering on a spectral characteristic of the biological tissue. Also, the feature amount acquisition unit acquires the feature amount Q based on the indicator X and the contribution C.