Patents by Inventor Toru Gotanda
Toru Gotanda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11427620Abstract: It is an object of the present invention to provide a transmission-blocking vaccine using an immunogenic protein which is specifically expressed in the oocyst stage of malaria parasites or a peptide fragment thereof, and an oral transmission-blocking vaccine capable of immunizing various animals involved in the malaria infectious cycle with such a vaccine. The present invention relates to a malaria transmission-blocking vaccine for oral administration containing an immunogenic protein derived from malaria parasite which is specifically expressed in the oocyst stage of malaria parasites or a peptide fragment thereof, and a method of blocking the transmission of malaria using the same.Type: GrantFiled: September 4, 2017Date of Patent: August 30, 2022Assignees: Hokusan Co., Ltd., National Institute of Advanced Industrial Science and Technology, School Juridical Person The Kitasato InstituteInventors: Noriko Tabayashi, Toru Gotanda, Hanae Sasaki, Noriko Itchoda, Uiko Kagaya, Takeshi Matsumura, Akira Ito, Hiromi Ikadai
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Publication number: 20210292382Abstract: It is an object of the present invention to provide a transmission-blocking vaccine using an immunogenic protein which is specifically expressed in the oocyst stage of malaria parasites or a peptide fragment thereof, and an oral transmission-blocking vaccine capable of immunizing various animals involved in the malaria infectious cycle with such a vaccine. The present invention relates to a malaria transmission-blocking vaccine for oral administration containing an immunogenic protein derived from malaria parasite which is specifically expressed in the oocyst stage of malaria parasites or a peptide fragment thereof, and a method of blocking the transmission of malaria using the same.Type: ApplicationFiled: September 4, 2017Publication date: September 23, 2021Applicants: Hokusan Co. Ltd., National Institute of Advanced Industrial Science and Technology, School Juridical Person The Kitasato InstituteInventors: Noriko Tabayashi, Toru Gotanda, Hanae Sasaki, Noriko Itchoda, Uiko Kagaya, Takeshi Matsumura, Akira Ito, Hiromi Ikadai
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Patent number: 10799448Abstract: The object of the present invention is to provide a therapeutic agent illustrating an immediate and sustained effect on chronic intractable external otitis. The present invention provide a composition, pharmaceutical composition, food and feed for preventing and/or treating chronic intractable external otitis, each comprising interferon-? (IFN?) as an active ingredient. Orally administering the composition of the present invention can provide inhibition, alleviation, treatment and prevention for chronic intractable external otitis. According to the present invention, IFN? can give a sufficient effect even when administered in a very small amount.Type: GrantFiled: January 12, 2016Date of Patent: October 13, 2020Assignees: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, HOKUSAN CO. LTDInventors: Akira Ito, Takeshi Matsumura, Toru Gotanda, Noriko Tabayashi, Noriko Itchoda, Takashi Aoki, Uiko Kagaya
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Publication number: 20190029953Abstract: The object of the present invention is to provide a therapeutic agent illustrating an immediate and sustained effect on chronic intractable external otitis. The present invention provide a composition, pharmaceutical composition, food and feed for preventing and/or treating chronic intractable external otitis, each comprising interferon-? (IFN?) as an active ingredient. Orally administering the composition of the present invention can provide inhibition, alleviation, treatment and prevention for chronic intractable external otitis. According to the present invention, IFN? can give a sufficient effect even when administered in a very small amount.Type: ApplicationFiled: January 12, 2016Publication date: January 31, 2019Applicants: National Institute of Advanced Industrial Science and Technology, Hokusan Co. LtdInventors: Akira Ito, Takeshi Matsumura, Toru Gotanda, Noriko Tabayashi, Noriko Itchoda, Takashi Aoki, Uiko Kagaya
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Patent number: 9629900Abstract: The present invention provides oral compositions which contain interferon ? (IFN?) as an active ingredient for preventing and/or treating periodontal disease. The number of causative microorganisms of periodontal disease can be suppressed by administering the compositions into the oral cavity. IFN? of the present invention can produce a sufficient effect even when administered at a very low dose. Furthermore, the compositions of the present invention can also be readily administered to animals such as dogs by formulating them into feed or such.Type: GrantFiled: February 24, 2015Date of Patent: April 25, 2017Assignees: Hokusan Co. Ltd., National Institute of Advanced Industrial Science and TechnologyInventors: Kuniaki Yoshioka, Ko Sato, Toru Gotanda, Akira Ito, Emiko Isogai, Kazuaki Takehara, Nobutoshi Maehara
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Publication number: 20160015787Abstract: The present invention provides oral compositions which contain interferon ? (IFN?) as an active ingredient for preventing and/or treating periodontal disease. The number of causative microorganisms of periodontal disease can be suppressed by administering the compositions into the oral cavity. IFN? of the present invention can produce a sufficient effect even when administered at a very low dose. Furthermore, the compositions of the present invention can also be readily administered to animals such as dogs by formulating them into feed or such.Type: ApplicationFiled: February 24, 2015Publication date: January 21, 2016Applicants: Hokusan Co. Ltd., National Institute of Advanced Industrial Science and TechnologyInventors: Kuniaki Yoshioka, Ko Sato, Toru Gotanda, Akira Ito, Emiko Isogai, Kazuaki Takehara, Nobutoshi Maehara
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Patent number: 8992905Abstract: The present invention provides oral compositions which contain interferon ? (IFN?) as an active ingredient for preventing and/or treating periodontal disease. The number of causative microorganisms of periodontal disease can be suppressed by administering the compositions into the oral cavity. IFN? of the present invention can produce a sufficient effect even when administered at a very low dose. Furthermore, the compositions of the present invention can also be readily administered to animals such as dogs by formulating them into feed or such.Type: GrantFiled: January 12, 2007Date of Patent: March 31, 2015Assignees: Hokusan Co. Ltd., National Institute of Advanced Industrial Science and TechnologyInventors: Kuniaki Yoshioka, Ko Sato, Toru Gotanda, Akira Ito, Emiko Isogai, Kazuaki Takehara, Nobutoshi Maehara
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Patent number: 8617575Abstract: Immunity against protozoan is conferred on an animal by a method comprising orally administering to an animal a transformed plant cell comprising a polynucleotide encoding a protective antigen against protozoiasis development, a transformed plant or its progeny or clone comprising the transformed cell, a propagation material of the plant or its progeny or clone, a processed material or extract of the above cell, plant, or its progeny or clone, or propagation material, or a protective antigen against protozoiasis development isolated from the transformed plant cell or the transformed plant or its progeny or clone.Type: GrantFiled: May 30, 2005Date of Patent: December 31, 2013Assignees: Kitasato Daiichi Sankyo Vaccine Co., Ltd., National Institute of Advanced Industrial Science and TechnologyInventors: Akira Ito, Toru Gotanda, Shigeki Kobayashi, Katsumi Kume, Takeshi Matsumura
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Publication number: 20110195091Abstract: When ELISA antibody titer dropped in chickens intramuscularly inoculated with an oil vaccine, recombinant HA and NP antigens prepared using gene recombinant technology were orally administered in combination with synthetic oligo CpG as a mucosal adjuvant to the chickens. Even when the immune response induced with the oil vaccine was impaired, the antibody titer was re-induced by orally administering the recombinant HA and NP antigens, and synthetic CpG-ODN in combination.Type: ApplicationFiled: August 13, 2009Publication date: August 11, 2011Applicant: THE KITASATO INSTITUTEInventors: Yukihiro Miyoshi, Akira Ito, Kentaro Susa, Naomi Himeno, Toru Gotanda
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Publication number: 20100202982Abstract: The present invention provides oral compositions which contain interferon ? (IFN?) as an active ingredient for preventing and/or treating periodontal disease. The number of causative microorganisms of periodontal disease can be suppressed by administering the compositions into the oral cavity. IFN? of the present invention can produce a sufficient effect even when administered at a very low dose. Furthermore, the compositions of the present invention can also be readily administered to animals such as dogs by formulating them into feed or such.Type: ApplicationFiled: January 12, 2007Publication date: August 12, 2010Inventors: Kuniaki Yoshioka, Ko Sato, Toru Gotanda, Akira Ito, Emiko Isogai, Kazuaki Takehara, Nobutoshi Maehara
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Publication number: 20080003243Abstract: Leaves of potato plants transformed with a vector that expresses an R7 immunogenic protein gene derived from second-generation schizonts of Leucocytozoon caulleryiwere administered to chickens as an oral vaccine. As a result, the present inventors succeeded in increasing the antibody titer of the chickens.Type: ApplicationFiled: May 30, 2005Publication date: January 3, 2008Applicant: THE KITASATO INSTITUTEInventors: Akira Ito, Toru Gotanda, Shigeki Kobayashi, Katsumi Kume, Takeshi Matsumura