Abstract: In a system including a plurality of multi-core processors, a table for managing the processors and cores owned by the processors is provided and a single virtual server is formed by using cores owned by different processors when generating the virtual server. According to the number owned by processors, the number of processors is varied. If a fault preecho in a processor is detected, control is exercised so as not to deliver an execution schedule of a virtualization mechanism to the processor in which the fault preecho has been detected. In a system including a plurality of multi-core processors, arithmetic cores owned by a plurality of different processors are assigned to processing of a process or thread in an operating system. In a system including a plurality of multi-core processors, arithmetic cores owned by a plurality of different processors are assigned to the operating system.

Abstract: A logical partitioned computer system. A hypervisor includes a resource management table for managing resources assigned to the hypervisor and an assigning/collecting unit for assigning and collecting resources to logical partitions. Each logical partiion has a guest resource monitoring unit for monitoring the amount of the resource being used out of the amount of the resource assigned to the logical partiion and an adding/separating unit for requesting addition and separation of a resource to the assigning/collecting unit based on results of monitoring. In response to the request, assigning/collecting unit searches resource management table, assigns a resource to logical partition when a reserve resource exists in case of an assignment request, and collects a resource as a reserve resource in the resource management table in case of a collection request.

Abstract: In an information processing system including host computers and disk devices, each of an execution-node host and a standby-node host includes an I/O request unit and an access-right change command unit. The I/O request unit issues an I/O request. The access-right change command unit transmits an access-right change command. The access-right change command results from causing I/O-enable/disable information and the host identification information to correspond to each other. The disk device includes an access control table, an access control unit, and an access-right change unit. The access control table stores information of the access-right change commands from the hosts. The access control unit judges the execution enablement/disablement for the I/O requests from the host identification information and the access control table.

Abstract: In an information processing system including host computers and disk devices, each of an execution-node host and a standby-node host includes an I/O request unit and an access-right change command unit. The I/O request unit issues an I/O request. The access-right change command unit transmits an access-right change command. The access-right change command results from causing I/O-enable/disable information and the host identification information to correspond to each other. The disk device includes an access control table, an access control unit, and an access-right change unit. The access control table stores information of the access-right change commands from the hosts. The access control unit judges the execution enablement/disablement for the I/O requests from the host identification information and the access control table.

Abstract: It is intended to provide a method of screening a candidate drug mainly metabolized by a drug metabolizing enzyme, CYP2D6, CYP2C9 or CYP2C19 with the use of a chimeric mouse carrying human hepatocytes transplanted thereinto, whereby it is determined whether or not the candidate drug is metabolized in a subject deficient in CYP2D6, CYP2C9 or CYP2C19. It is also intended to provide a method of determining whether or not a candidate drug induces or inhibits the activity of any of drug metabolizing enzymes, CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4 with the use of a chimeric mouse carrying human hepatocytes transplanted thereinto.

Abstract: The invention provides a method for precisely predicting the metabolism of a drug in human liver and the effect of the drug on liver function. The invention provides a method for predicting a metabolite of a test substance produced in human liver and functions of the liver, wherein the method includes administering a test substance to a nonhuman chimeric animal and a non-chimeric animal of the same species, wherein the chimeric animal intracorporeally carries a population of human-origin hepatocytes having proliferation potential and in which the hepatocyte, population substantially functions as the liver of the chimeric animal, and wherein these animals are protected from the attack by a human complement produced by the hepatocytes; and analyzing and comparing metabolites from the chimeric animal and the non-chimeric animal.

Abstract: In a system including a plurality of multi-core processors, a table for managing the processors and cores owned by the processors is provided and a single virtual server is formed by using cores owned by different processors when generating the virtual server. According to the number owned by processors, the number of processors is varied. If a fault preecho in a processor is detected, control is exercised so as not to deliver an execution schedule of a virtualization mechanism to the processor in which the fault preecho has been detected. In a system including a plurality of multi-core processors, arithmetic cores owned by a plurality of different processors are assigned to processing of a process or thread in an operating system. In a system including a plurality of multi-core processors, arithmetic cores owned by a plurality of different processors are assigned to the operating system.

Abstract: In a fuel injection valve (1) having a nozzle body (31) with a nozzle hole (35) at its tip that is opened and closed by a nozzle needle (32) housed in the nozzle body (31), the area of contact between the nozzle needle (32) and a seat (31A) on the nozzle body (31) is provided with a coating layer (Y) to reduce the frictional resistance with the nozzle body (31). When the nozzle needle (32) seats on the seat (31A), between the time from when the tip of the nozzle needle (32) contacts the seat (31A) to when it is pressed against the seat (31A), the nozzle needle (32) slides on the surface of the nozzle body (31) with low frictional resistance. As a result, wear on the seat (31A) when the nozzle needle (32) is seated to open the valve can be kept down.

Abstract: A logical partitioned computer system. A hypervisor includes a resource management table for managing resources assigned to the hypervisor and an assigning/collecting unit for assigning and collecting resources to logical partitions. Each logical partiion has a guest resource monitoring unit for monitoring the amount of the resource being used out of the amount of the resource assigned to the logical partiion and an adding/separating unit for requesting addition and separation of a resource to the assigning/collecting unit based on results of monitoring. In response to the request, assigning/collecting unit searches resource management table, assigns a resource to logical partition when a reserve resource exists in case of an assignment request, and collects a resource as a reserve resource in the resource management table in case of a collection request.

Abstract: In an information processing system including host computers and disk devices, each of an execution-node host and a standby-node host includes an I/O request unit and an access-right change command unit. The I/O request unit issues an I/O request. The access-right change command unit transmits an access-right change command. The access-right change command results from causing I/O-enable/disable information and the host identification information to correspond to each other. The disk device includes an access control table, an access control unit, and an access-right change unit. The access control table stores information of the access-right change commands from the hosts. The access control unit judges the execution enablement/disablement for the I/O requests from the host identification information and the access control table.

Abstract: A logical partitioned computer system. A hypervisor includes a resource management table for managing resources assigned to the hypervisor and an assigning/collecting unit for assigning and collecting resources to logical partitions. Each logical partition has a guest resource monitoring unit for monitoring the amount of the resource being used out of the amount of the resource assigned to the logical partition and an adding/separating unit for requesting addition and separation of a resource to the assigning/collecting unit based on results of monitoring. In response to the request, assigning/collecting unit searches resource management table, assigns a resource to logical partition when a reserve resource exists in case of an assignment request, and collects a resource as a reserve resource in the resource management table in case of a collection request.

Abstract: A new benzodioxole derivative has a substituent in the phenyl ring which is a carboxyalkylthioalkyl or the like and is effective to treat a liver disease.

Abstract: The present invention provides a novel benzene derivative useful as a preventive and medically treating medicine for arteriosclerosis, and a cholesterol O-acyl transferase inhibitor comprising the benzene derivative as an active ingredient.The benzene derivative according to the present invention is represented by the following general formula (I): ##STR1## wherein R.sup.1 represents a carboxyl group which may be protected or a group represented by the formula: ##STR2## wherein R.sup.5 represents a lower alkyl group or a hydroxyalkyl group and R.sup.6 represents a hydrogen atom or a hydroxyl group; R.sup.2 represents a hydrogen atom, a lower alkyl group or the like; R.sup.3 and R.sup.4 each represent a hydrogen atom or a hydroxyl group; and p is an integer of 1 to 6.

Abstract: Compounds of the formula: ##STR1## where R.sup.1 is a hydrogen atom or a lower alkyl group;R.sub.2 is a lower alkoxy group;R.sub.3 is a group ##STR2## Z is represented by the formula: ##STR3## where R.sub.2 and R.sub.3 may be the same or different from each other and each stands for a hydrogen atom or a lower alkyl;Y is represented by the formula: --(CH.sub.2).sub.n -- where n is 0 or an integer of 1 to 2 or a group represented by the formula: ##STR4## where R.sup.2 and R.sup.3 may be the same or different from each other and each stands for a lower alkyl group; andR.sup.4 represents a group of the formula: ##STR5## where p is 0 or an integer of 1 to 3 and R.sup.12 is hydrogen, a halogen atom, a lower alkyl or a lower alkoxy group a hydrogen atom, R.sup.2 is a methoxy group, R.sup.3 is a hydroxy group and R.sup.4 is a benzyl group having anti-inflammatory activity.

Abstract: A new benzodioxole derivative has a substituent in the phenyl ring which is a carboxyalkylthioalkyl or the like and is effective to treat a liver disease.

Abstract: Compounds of the formula: ##STR1## where R.sup.1 is a hydrogen atom or a lower alkyl group;R.sub.2 is a lower alkoxy group;R.sub.3 is a hydroxyl or lower alkoxy group;Z is represented by the formula: ##STR2## where R.sub.2 and R.sub.3 may be the same or different from each other and each stands for a hydrogen atom or a lower alkyl;Y is represented by the formula: --(CH.sub.2).sub.n -- where n is 0 or an integer of 1 to 2 or a group represented by the formula: ##STR3## where R.sup.2 and R.sup.3 may be the same or different from each other and each stands for a lower alkyl group; andR.sup.4 represents a group of the formula: ##STR4## where p is 0 or an integer of 1 to 3 and R.sup.12 is hydrogen, a halogen atom, a lower alkyl or a lower alkoxy group a hydrogen atom, R.sup.2 is a methoxy group, R.sup.3 is a hydroxy group and R.sup.4 is a benzyl group having anti-inflammatory activity.

Abstract: The present invention relates to a naphthalene derivative. More particularly, it relates to a naphthalene derivative exhibiting an excellent activity as a drug.

Abstract: A new benzodioxole derivative has a substituent in the phenyl ring which is a carboxyalkylthioalkyl or the like and is effective to treat a liver disease.