Abstract: A method for manufacturing a forged article, capable of improving the durability of a die for forging is provided. The method, includes forging a steel material, by using a die, by spraying or applying a water-soluble polymer lubricant containing 0.01 to 0.98 mass % of a water-soluble sulfate onto a working surface of the die, the die being made of a raw material having a constituent composition of by mass %, of 0.4 to 0.7% of C, 1.0% or less of Si, 1.0% or less of Mn, 4.0 to 6.0% of Cr, 2.0 to 4.0% of (Mo+½W), 0.5 to 2.5% of (V+Nb), 0 to 1.0% of Ni, 0 to 5.0% of Co, 0.02% or less of N, and a remnant composed of Fe and impurities, and having hardness of 55 to 60 HRC, and the die including a nitrided layer or a nitrosulfidized layer on the working surface thereof.

Abstract: Provided is a gel particle measuring apparatus for detecting scattered light generated by light irradiation at a production start time point of a gel particle, and performing measurement promptly and accurately while suppressing attenuation of the scattered light in a solvent in which the phenomenon occurs.

Abstract: Provided is a gel particle measuring apparatus for detecting scattered light generated by light irradiation at a production start time point of a gel particle, and performing measurement promptly and accurately while suppressing attenuation of the scattered light in a solvent in which the phenomenon occurs.

Abstract: To measure a starting point of production of gel particles with high sensitivity in measurement of a target substance in a sample through a gelation reaction while minimizing light attenuation in a solvent in which a phenomenon occurs, provided is a gel particle measurement device including: a sample cuvet (1) accommodating a sample (S) and a solution containing a reagent (R); stirring means (2) for stirring a mixed solution (W); an incident light source (3) for irradiating the mixed solution (W) with coherent light (Bm); backscattered light detecting means (4) provided outside the sample cuvet (1) on the same side on which the incident light source (3) is provided, the backscattered light detecting means (4) detecting a backscattered light component, which returns toward the incident light source, in the light scattered in the mixed solution (W) in the sample cuvet (1); scattered light fluctuation measuring means (5) for measuring a fluctuation component of backscattered light based on a detection output fro

Abstract: Provided is a gel particle measurement reagent effective in quickly measuring a time point of initiation of production of gel particles. A gel particle measurement reagent R is a gel particle measurement reagent to be used to be agitated continuously with a sample S containing a target substance St as a measuring object to turn the target substance St into gel particles, including: a reagent base material 1 that undergoes a gelation reaction with the target substance St; and a biologically inactive particle formation accelerating factor 2 that is added to the reagent base material, has solubility in the sample S and dissolves therein at a concentration of 0.002 to 1%, and accelerates production of gel particles G whose particle sizes are centered in a predetermined range.

Abstract: Provided is a gel particle measurement reagent effective in quickly measuring a time point of initiation of production of gel particles. A gel particle measurement reagent R is a gel particle measurement reagent to be used to be agitated continuously with a sample S containing a target substance St as a measuring object to turn the target substance St into gel particles, including: a reagent base material 1 that undergoes a gelation reaction with the target substance St; and a biologically inactive particle formation accelerating factor 2 that is added to the reagent base material, has solubility in the sample S and dissolves therein at a concentration of 0.002 to 1%, and accelerates production of gel particles G whose particle sizes are centered in a predetermined range.

Abstract: In a measuring apparatus for measuring a target substance in a sample cell via a gelation reaction, a sample cell houses a specimen containing the substance to be measured, and a solution containing a gelating reagent is irradiated with a laser beam. The solution in the sample cell is stirred to generate minute and uniform gel particles, which are caused to pass through the laser beam. Scattered light from the gel particles generated in the sample cell is detected by a photodiode array, and the scattered-light intensity of the generated gel particles or the diameter and the number thereof is measured on time series by a computer on the basis of a scattered-light detection output of the photodiode array.

Abstract: A gel particle measuring apparatus detects a gel particle production starting point with high sensitivity, for measurement of a target substance in a sample by a gelation reaction. The gel particle measuring apparatus includes a sample cell accommodating a sample and a solution containing a reagent, a stirring device for stirring a mixed solution including the sample and the solution containing the reagent, a coherent light source that irradiates the mixed solution with coherent light, a transmitted light detecting device outside the sample cell, on the opposite side of the coherent light source, a transmitted light fluctuation detecting device for detecting a fluctuation component of the transmitted light, and a gel particle production determining device for determining at least the production state of gel particles, which leads to timing of phase transition of the mixed solution from a sol phase to a gel phase.

Abstract: To measure a starting point of production of gel particles with high sensitivity in measurement of a target substance in a sample through a gelation reaction while minimizing light attenuation in a solvent in which a phenomenon occurs, provided is a gel particle measurement device including: a sample cuvet (1) accommodating a sample (S) and a solution containing a reagent (R); stirring means (2) for stirring a mixed solution (W); an incident light source (3) for irradiating the mixed solution (W) with coherent light (Bm); backscattered light detecting means (4) provided outside the sample cuvet (1) on the same side on which the incident light source (3) is provided, the backscattered light detecting means (4) detecting a backscattered light component, which returns toward the incident light source, in the light scattered in the mixed solution (W) in the sample cuvet (1); scattered light fluctuation measuring means (5) for measuring a fluctuation component of backscattered light based on a detection output fro

Abstract: Provided is a gel particle measuring apparatus for detecting a gel particle production starting point with high sensitivity in the measurement of a target substance in a sample by a gelation reaction.

Abstract: It is intended to allow the concentration of a substance such as an endotoxin or ?-D glucan measured via gelation reactions to be measured in a short time and at a high sensitivity and a high specificity. In a measuring apparatus for measuring a target substance in a sample cell via a gelation reaction, a sample cell 13 for housing a specimen containing the substance to be measured and a solution containing a gelating reagent is irradiated with a laser beam from a semiconductor laser 11. The solution in the sample cell is stirred by a stir bar 25 to generate minute and uniform gel particles, which are caused to pass through the laser beam. Scattered light from the gel particles generated in the sample cell 13 is detected by a photodiode array 18, and a scattered-light intensity of the generated gel particles or the diameter and the number thereof is measured on time series by a computer 21 on the basis of a scattered-light detection output of the photodiode array.