Patents by Inventor Toru Sawai

Toru Sawai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening method
    Publication number: 20100168014
    Abstract: The present inventors have found that relaxin-3 has a feeding-stimulating activity, a body weight increasing activity, and fat weight increasing activity by intracerebroventricularly administering relaxin-3 to rats and observing the amount of feeding, body weight and fat weight, and so on after the administration. According to the present invention, a polypeptide having useful effects in stimulating feeding, increasing body weight, and fattening; a therapeutic agent containing said polypeptide; a method of screening for a compound, a substance, or a salt thereof which activates or suppresses a receptor of said polypeptide; a kit for said screening; and an agent which comprises a substance which inhibits expression of said polypeptide, such as a feeding-surpressing agent, a therapeutic agent for the treatment of obesity, and a therapeutic agent for the treatment of diabetes.
    Type: Application
    Filed: November 9, 2009
    Publication date: July 1, 2010
    Inventors: Takayuki Hida, Tomoko Sekiya, Toru Sawai, Takashi Seiki, Eiki Takahashi, Michiko Kosasa, Kokichi Harada, Toru Arai
  • Methods of affecting feeding and weight in mammals by administration of relaxin-3
    Patent number: 7638490
    Abstract: Relaxin-3 is found to have feeding-stimulating activity, body weight increasing activity, and fat weight increasing activity when intracerebroventricularly administered to rats through observation of amount of feeding, body weight and fat weight after administration of relaxin-3. This invention includes: a polypeptide having useful effects in stimulating feeding, increasing body weight, and fattening; a therapeutic agent containing the polypeptide; a method of screening for a compound, a substance, or a salt thereof which activates or suppresses a receptor of the polypeptide; a kit for screening; and an agent with a substance which inhibits expression of the polypeptide, such as a feeding-suppressing agent, a therapeutic agent for the treatment of obesity, and a therapeutic agent for the treatment of diabetes.
    Type: Grant
    Filed: February 9, 2005
    Date of Patent: December 29, 2009
    Assignee: Eisai R&D Managment Co., Ltd.
    Inventors: Takayuki Hida, Tomoko Sekiya, Toru Sawai, Takashi Seiki, Eiki Takahashi, Michiko Kosasa, Kokichi Harada, Tohru Arai
  • Method of screening for antianxiety drugs
    Patent number: 7501395
    Abstract: An anxiolytic drug of the invention comprises an orexin receptor antagonist, a pharmacologically acceptable salt thereof, or a solvate thereof as an active ingredient. A method for screening a compound having an anxiolytic action of the invention comprises a step of using orexin-A.
    Type: Grant
    Filed: April 25, 2006
    Date of Patent: March 10, 2009
    Assignee: Eisai R & D Management Co., Ltd.
    Inventors: Toru Sawai, Michiyuki Suzuki, Carsten Beuckmann, Kodo Shikata
  • ANTIANXIETY DRUGS AND A METHOD OF SCREENING THE SAME
    Publication number: 20070160538
    Abstract: An anxiolytic drug of the invention comprises an orexin receptor antagonist, a pharmacologically acceptable salt thereof, or a solvate thereof as an active ingredient. A method for screening a compound having an anxiolytic action of the invention comprises a step of using orexin-A.
    Type: Application
    Filed: April 25, 2006
    Publication date: July 12, 2007
    Applicant: Eisai Co., Ltd.
    Inventors: Toru Sawai, Michiyuki Suzuki, Carsten Beuckmann, Kodo Shikata
  • Screening method
    Publication number: 20070054850
    Abstract: The present inventors have found that relaxin-3 has a feeding-stimulating activity, a body weight increasing activity, and fat weight increasing activity by intracerebroventricularly administering relaxin-3 to rats and observing the amount of feeding, body weight and fat weight, and so on after the administration. According to the present invention, a polypeptide having useful effects in stimulating feeding, increasing body weight, and fattening; a therapeutic agent containing said polypeptide; a method of screening for a compound, a substance, or a salt thereof which activates or suppresses a receptor of said polypeptide; a kit for said screening; and an agent which comprises a substance which inhibits expression of said polypeptide, such as a feeding-surpressing agent, a therapeutic agent for the treatment of obesity, and a therapeutic agent for the treatment of diabetes.
    Type: Application
    Filed: February 9, 2005
    Publication date: March 8, 2007
    Inventors: Takayuki Hida, Tomoko Sekiya, Toru Sawai, Takashi Seiki, Eiki Takahashi, Michiko Kosasa, Kokichi Harada, Tohru Arai