Patents by Inventor Toru Shinzato
Toru Shinzato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11467170Abstract: A dose determination program for an erythropoiesis-stimulating agent that is executable by a computer. The program causes the computer to perform: obtaining a predetermined target hemoglobin concentration; obtaining a first concentration and a first dose in a stable state in which a hemoglobin concentration is stable at the first concentration by repeatedly administering the first dose a plurality of times, and calculating a second dose of the erythropoiesis-stimulating agent based on the obtained target hemoglobin concentration, the obtained first concentration, and the obtained first dose, the second dose of the erythropoiesis-stimulating agent being to be administered by a fixed amount.Type: GrantFiled: July 17, 2018Date of Patent: October 11, 2022Assignee: NIPRO CORPORATIONInventors: Toru Shinzato, Wataru Mizuno, Hidetoshi Saio
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Patent number: 11241160Abstract: Disclosed herein is a blood pressure measuring device including: a pressure measuring tool 110; a fastening member 120 configured to fasten the pressure measuring tool 110 in rest position onto a skin region covering an anastomotic region of a shunt blood vessel 201; and a control circuit 130 configured to receive an input signal from the pressure measuring tool 110 and to process the input signal to calculate a pressure inside the anastomotic region of the shunt blood vessel 201.Type: GrantFiled: March 23, 2016Date of Patent: February 8, 2022Assignee: NIPRO CORPORATIONInventors: Toru Shinzato, Masamiki Miwa, Mitsutaka Ueda, Makoto Mitsuhashi, Hironori Numoto
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Publication number: 20210187178Abstract: An extracellular fluid volume calculator may include: an acquirement unit configured to acquire a membrane area of a dialyzer used for hemodialysis; and a processor configured to calculate a post-hemodialysis extracellular fluid volume based on a difference between a pre-hemodialysis amount of uric acid and a post-hemodialysis amount of uric acid. The processor may be configured to: calculate a removal amount of uric acid removed by hemodialysis based on a dialyzer overall mass transfer-area coefficient for uric acid; and calculate the dialyzer overall mass transfer-area coefficient for uric acid based on the membrane area of the dialyzer acquired by the acquirement unit.Type: ApplicationFiled: August 21, 2019Publication date: June 24, 2021Applicant: NIPRO CORPORATIONInventors: Toru SHINZATO, Masamiki MIWA, Wataru MIZUNO
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Publication number: 20200345916Abstract: An extracellular fluid volume calculator may include: a first acquirement unit configured to acquire a pre-hemodialysis plasma uric acid concentration, a post-hemodialysis plasma uric acid concentration, a removal amount of uric acid by hemodialysis, and a removal volume of water during hemodialysis; and a first processor configured to calculate an extracellular fluid volume based on a difference between a pre-hemodialysis amount of uric acid and a post-hemodialysis amount of uric acid, the difference being determined based on the pre-hemodialysis plasma uric acid concentration, the post-hemodialysis plasma uric acid concentration, the removal amount of uric acid, and the removal volume of water acquired by the first acquirement unit.Type: ApplicationFiled: December 27, 2018Publication date: November 5, 2020Inventors: Toru SHINZATO, Masamiki MIWA
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Publication number: 20200200770Abstract: A dose determination program for an erythropoiesis-stimulating agent that is executable by a computer. The program causes the computer to perform: obtaining a predetermined target hemoglobin concentration; obtaining a first concentration and a first dose in a stable state in which a hemoglobin concentration is stable at the first concentration by repeatedly administering the first dose a plurality of times, and calculating a second dose of the erythropoiesis-stimulating agent based on the obtained target hemoglobin concentration, the obtained first concentration, and the obtained first dose, the second dose of the erythropoiesis-stimulating agent being to be administered by a fixed amount.Type: ApplicationFiled: July 17, 2018Publication date: June 25, 2020Applicant: NIPRO CORPORATIONInventors: Toru SHINZATO, Wataru MIZUNO, Hidetoshi SAIO
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Patent number: 10496794Abstract: A method of determining an ESA dose, which allows a hemoglobin concentration in the blood to be stably maintained at a target value, and which can decrease a range of fluctuation of the hemoglobin concentration with respect to the target value. The method comprises the steps of: setting the target value of the hemoglobin concentration in the blood; calculating a target value of a hemoglobin production rate which allows the hemoglobin concentration to reach the target value; calculating a serum ESA concentration which allows the hemoglobin production rate to reach the target value, from a relationship between the hemoglobin production rate and the ESA concentration; and calculating an amount of administration of an ESA which gives the serum ESA concentration, from a relationship between the ESA concentration and the amount of administration of the ESA, to determine an ESA dose which allows the hemoglobin concentration to reach the target value.Type: GrantFiled: December 7, 2015Date of Patent: December 3, 2019Assignee: NIPRO CORPORATIONInventors: Toru Shinzato, Yasuyo Maruyama, Fumihiko Ueno
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Publication number: 20180070838Abstract: Disclosed herein is a blood pressure measuring device including: a pressure measuring tool 110; a fastening member 120 configured to fasten the pressure measuring tool 110 in rest position onto a skin region covering an anastomotic region of a shunt blood vessel 201; and a control circuit 130 configured to receive an input signal from the pressure measuring tool 110 and to process the input signal to calculate a pressure inside the anastomotic region of the shunt blood vessel 201.Type: ApplicationFiled: March 23, 2016Publication date: March 15, 2018Inventors: Toru SHINZATO, Masamiki MIWA, Mitsutaka UEDA, Makoto MITSUHASHI, Hironori NUMOTO
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Publication number: 20180001034Abstract: The present invention suppresses the formation of a pocket in a wall of a puncture route when a dull needle is moved forward along the puncture route. In order to achieve such aim, the invention provides a needle to be inserted into a puncture route extending from skin to a blood vessel under the skin to puncture the blood vessel, wherein: the needle is formed in a tubular shape and has an inclined end face at a tip of the needle, the inclined end face being inclined relative to an axis of the needle, a tip end of the inclined end face defining an unsharp edge; the needle has a flexibility of needle elastic modulus nE=1-900 Nmm as defined by an equation to be set forth below; a material of the needle is a resin; and the needle is manufactured by injection molding using a ring-shaped gate.Type: ApplicationFiled: January 15, 2016Publication date: January 4, 2018Applicants: ASAHI KASEI MEDICAL CO., LTD., NEXTIER CORPORATION, TOGO MEDIKIT CO., LTD.Inventors: Masatomi SASAKI, Toru SHINZATO, Yasuyo MARUYAMA, Fumitaka SHIGENOBU
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Publication number: 20160184127Abstract: An airway is secured without obstructing sleep even when the lingual radix falls into the airway. An airway expansion apparatus is configured to include a pillow portion that supports a cranial portion, a pair of left and right mandible holding portions that hold the mandible coupled to the cranial portion at the temporomandibular joint, a first actuation mechanism that causes the mandible holding portions to come into contact with the mandible, and a second actuation mechanism that lifts the mandible holding portions with respect to the pillow portion with the mandible holding portions kept in contact with the mandible, in which the mandible is kept lifted.Type: ApplicationFiled: August 6, 2014Publication date: June 30, 2016Applicants: FUSO PHARMACEUTICAL INDUSTRIES, LTD., NEXTIERInventors: Toru SHINZATO, Yuzuru KITAHARA
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Publication number: 20160085939Abstract: A method of determining an ESA dose, which allows a hemoglobin concentration in the blood to be stably maintained at a target value, and which can decrease a range of fluctuation of the hemoglobin concentration with respect to the target value. The method comprises the steps of: setting the target value of the hemoglobin concentration in the blood; calculating a target value of a hemoglobin production rate which allows the hemoglobin concentration to reach the target value; calculating a serum ESA concentration which allows the hemoglobin production rate to reach the target value, from a relationship between the hemoglobin production rate and the ESA concentration; and calculating an amount of administration of an ESA which gives the serum ESA concentration, from a relationship between the ESA concentration and the amount of administration of the ESA, to determine an ESA dose which allows the hemoglobin concentration to reach the target value.Type: ApplicationFiled: December 7, 2015Publication date: March 24, 2016Inventors: Toru SHINZATO, Yasuyo MARUYAMA, Fumihiko UENO
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Patent number: 9199024Abstract: A hemodialysis system includes a body fluid volume calculating unit, a dialysis condition input unit with which blood flow velocity and dialysis fluid flow velocity in hemodialysis treatment performed after specific hemodialysis treatment can be input and input values of the blood flow velocity and the dialysis fluid flow velocity can be adjusted, a dialysis dose calculating unit configured to calculate, when the blood flow velocity and the dialysis fluid flow velocity are input to the dialysis condition input unit, by analyzing a mathematical model concerning urea kinetics, a dialysis dose of the hemodialysis treatment from the input blood flow velocity and the input dialysis fluid flow velocity, a body fluid volume calculated by the body fluid volume calculating unit, and the like, and a dialysis dose display unit configured to display the hemodialysis dose calculated by the dialysis dose calculating unit.Type: GrantFiled: July 14, 2011Date of Patent: December 1, 2015Assignees: ASAHI KASEI MEDICAL CO., LTD., NEXTIER CORPORATIONInventors: Masatomi Sasaki, Toru Shinzato, Masayo Maruyama, Masamiki Miwa
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Publication number: 20150157359Abstract: The success rate of the insertion of a dull needle into a puncture hole is improved. A puncture needle is provided which is inserted into a puncture route that is formed to cover from a skin surface to a shunt vessel surface so as to expand an incision of a puncture hole formed in the shunt vessel surface. The puncture needle has an inclined end face that is inclined toward a front end of the needle, and a front end part of the inclined end face has an edge having no sharpness. Right and left side parts of the inclined end face which are contiguous with the front end part are respectively inclined outward, and side edges of the side parts are provided with cutting lines.Type: ApplicationFiled: June 13, 2013Publication date: June 11, 2015Applicants: ASAHI KASEI MEDICAL CO., LTD., NEXTIER CORPORATIONInventors: Toru Shinzato, Masamiki Miwa, Yasuyo Maruyama, Masatomi Sasaki
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Patent number: 8950027Abstract: A respiratory tract widening tool capable of reliably managing a respiratory tract in a supine posture and freely changing the posture, and a respiratory tract widening unit provided therewith are provided.Type: GrantFiled: December 21, 2010Date of Patent: February 10, 2015Assignees: Fuso Pharmaceutical Industries, Ltd., NextierInventors: Keiichi Yamamoto, Yuzuru Kitahara, Yasuyo Maruyama, Toru Shinzato
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Publication number: 20130158461Abstract: A hemodialysis system includes a body fluid volume calculating unit, a dialysis condition input unit with which blood flow velocity and dialysis fluid flow velocity in hemodialysis treatment performed after specific hemodialysis treatment can be input and input values of the blood flow velocity and the dialysis fluid flow velocity can be adjusted, a dialysis dose calculating unit configured to calculate, when the blood flow velocity and the dialysis fluid flow velocity are input to the dialysis condition input unit, by analyzing a mathematical model concerning urea kinetics, a dialysis dose of the hemodialysis treatment from the input blood flow velocity and the input dialysis fluid flow velocity, a body fluid volume calculated by the body fluid volume calculating unit, and the like, and a dialysis dose display unit configured to display the hemodialysis dose calculated by the dialysis dose calculating unit.Type: ApplicationFiled: July 14, 2011Publication date: June 20, 2013Applicants: NEXTIER CORPORATION, ASAHI KASEI MEDICAL CO., LTD.Inventors: Masatomi Sasaki, Toru Shinzato, Masayo Maruyama, Masamiki Miwa
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Patent number: 8419646Abstract: To provide a non-invasive blood pressure estimation apparatus, which can accurately estimate systolic blood pressure from blood flow sound of a dialysis patient and continuously estimate systolic blood pressure by continuously picking up the blood flow sound. A blood pressure estimation apparatus creates a standard pulse curve by relating a start point and end point of a rising phase of a pulse wave to diastolic blood pressure and systolic blood pressure, respectively, creates a correspondence curve between blood flow sound power and estimated blood pressure by contrasting the standard pulse curve with the blood flow sound power curve obtained from blood flow sound at a shut site, with the two curves plotted on the same time axis, derives a systolic blood pressure estimation linear function from the correspondence curve, inputs a measured maximum value of the blood flow sound power into the linear function, and thereby estimates systolic blood pressure.Type: GrantFiled: April 9, 2009Date of Patent: April 16, 2013Assignees: Asahi Kasei Kabushiki Kaisha, Nextier CorporationInventors: Masatoshi Saito, Sakae Omura, Toru Shinzato
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Publication number: 20130025058Abstract: A respiratory tract widening tool capable of reliably managing a respiratory tract in a supine posture and freely changing the posture, and a respiratory tract widening unit provided therewith are provided.Type: ApplicationFiled: December 21, 2010Publication date: January 31, 2013Applicants: NEXTIER, FUSO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Keiichi Yamamoto, Yuzuru Kitahara, Yasuyo Maruyama, Toru Shinzato
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Publication number: 20110295152Abstract: The present invention is a method of puncturing a shunt blood vessel, using a incision needle having a pointed extremity that protrudes apically from a hypothetical angled plane formed by cutting straight through the tip of the needle at an angle, wherein the pointed extremity of the incision needle is inserted into a shunt blood vessel, thereby forming a reverse U-shaped incision on the surface of the shunt blood vessel, with the apex of the incision being on the bottom side in the direction of insertion.Type: ApplicationFiled: May 25, 2011Publication date: December 1, 2011Applicants: NEXTIER CORPORATION, ASAHI KASEI KURARAY MEDICAL CO., LTD.Inventors: Masatomi SASAKI, Toru SHINZATO, Yasuyo MARUYAMA, Yukie SHIONOYA
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Publication number: 20110125033Abstract: [Problem to be Solved] To provide a non-invasive blood pressure estimation apparatus which can accurately estimate systolic blood pressure from blood flow sound of a dialysis patient and can continuously estimate systolic blood pressure by continuously picking up the blood flow sound of the subject. [Solution] A blood pressure estimation apparatus creates a standard pulse curve by relating a start point and end point of a rising phase of a pulse wave to diastolic blood pressure and systolic blood pressure, respectively, creates a correspondence curve between blood flow sound power and estimated blood pressure by contrasting the standard pulse curve with the blood flow sound power curve obtained from blood flow sound at a shut site, with the two curves plotted on the same time axis, derives a systolic blood pressure estimation linear function from the correspondence curve, inputs a measured maximum value of the blood flow sound power into the linear function, and thereby estimates systolic blood pressure.Type: ApplicationFiled: April 9, 2009Publication date: May 26, 2011Applicants: ASAHI KASEI KABUSHIKI KAISHA, Nextier CorporationInventors: Masatoshi Saito, Sakae Omura, Toru Shinzato
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Publication number: 20060155318Abstract: A pin for forming a hole for inserting an indwelling needle for minimize a load exerted to a living body, and a jig for installing the hole-forming pin from a skin surface are provided.Type: ApplicationFiled: July 24, 2003Publication date: July 13, 2006Inventors: Toru Shinzato, Shigeki Toma, Yoshihiko Sano, Toshiaki Masuda, Futoshi Yamaguchi, Kazuyoshi Harada, Nobuo Takagi, Masahisa Tanimoto
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Patent number: 5370123Abstract: A blood clarification device wherein a means for measuring blood pressure comprises (a) a needle-detector which is much thinner than the puncture needle and capable of being smoothly inserted into a blood vessel from outside through an inner aperture of the puncture needle, (b) an insertion aperture, for allowing fluid-tight insertion of the needle-detector, positioned on a wall of the blood supply passage in the vicinity of the puncture needle, and (c) a pressure transducer for detecting the blood pressure inside the blood vessel transmitted thereto via the needle-detector. In a blood clarification apparatus of the present invention, blood pressure inside a blood vessel is transmitted to a pressure transducer via a needle-detector during dialysis/filtration operation and blood pressure of a patient is detected continuously and automatically by the pressure transducer.Type: GrantFiled: November 5, 1993Date of Patent: December 6, 1994Assignees: Nissho Corporation, Toru ShinzatoInventor: Toru Shinzato