Abstract: When the secondary structure is an ?-helix, moving averages of hydrophobic value are calculated respectively for odd-numbered amino acid residues and even-numbered amino acid residues in an amino acid sequence to be analyzed, and broken line graphs are created from the moving averages. When the secondary structure is a ?-sheet, moving averages of hydrophobic value are calculated respectively for amino acid residues appearing every 3.6 residues and amino acid residues shifted 1.8 residues therefrom in the amino acid sequence to be analyzed, and broken line graphs are created from the moving averages. In the cases of ?-helix and ?-sheet, a region where one of the two broken lines is at a level higher than a predetermined threshold is determined as a secondary structure region candidate.

Abstract: A method of mapping cDNA sequences is disclosed to enable searching for matching portions between a large number of cDNA sequences and genome sequences in a short period of time. cDNA sequences sharing high homology are grouped from among a large number of cDNA sequences. A consensus sequence 701 maximally matching any of the sequences within the group is created. Matching portions between the sequence and a genome sequence 702 are searched for, and then a partial sequence 706 containing the matching portions is extracted. Matching portions between the partial sequence and cDNA sequences within the group are searched for. Accordingly, the number of instances of searching for matching portions from genome sequences is reduced so as to shorten the processing time.