Patents by Inventor Torunn Tjelle

Torunn Tjelle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Device and method for single-needle in vivo electroporation
    Patent number: 11331479
    Abstract: Described is a device and method for administration of molecules to tissue in vivo for various medical applications, the device comprising a single hypodermic injection needle and at least two spaced elongate electrodes which provide for the ability, when the needle is inserted into tissue, such as skin or muscle, to pulse tissue with a non-uniform electric field sufficient to cause reversible poration of cells lying along or in close proximity to the track made by the needle upon its insertion into said tissue.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: May 17, 2022
    Assignee: Inovio Pharmaceuticals, Inc.
    Inventors: Rune Kjeken, Iacob Mathiesen, Elisabeth Torunn Tjelle, George McHugh
  • DEVICE AND METHOD FOR SINGLE-NEEDLE IN VIVO ELECTROPORATION
    Publication number: 20200001076
    Abstract: Described is a device and method for administration of molecules to tissue in vivo for various medical applications, the device comprising a single hypodermic injection needle and at least two spaced elongate electrodes which provide for the ability, when the needle is inserted into tissue, such as skin or muscle, to pulse tissue with a non-uniform electric field sufficient to cause reversible poration of cells lying along or in close proximity to the track made by the needle upon its insertion into said tissue.
    Type: Application
    Filed: July 9, 2019
    Publication date: January 2, 2020
    Inventors: Rune KJEKEN, Iacob MATHIESEN, Elisabeth Torunn TJELLE, George McHUGH
  • Device and method for single-needle in vivo electroporation
    Patent number: 10369359
    Abstract: Described is a device and method for administration of molecules to tissue in vivo for various medical applications, the device comprising a single hypodermic injection needle and at least two spaced elongate electrodes which provide for the ability, when the needle is inserted into tissue, such as skin or muscle, to pulse tissue with a non-uniform electric field sufficient to cause reversible poration of cells lying along or in close proximity to the track made by the needle upon its insertion into said tissue.
    Type: Grant
    Filed: February 9, 2007
    Date of Patent: August 6, 2019
    Assignee: Genetronics, Inc.
    Inventors: Rune Kjeken, Iacob Mathiesen, Elisabeth Torunn Tjelle, George McHugh
  • Electroporation device and injection apparatus
    Publication number: 20080234655
    Abstract: An apparatus is provided for injecting a fluid into body tissue, the apparatus comprising: a hollow needle; and fluid delivery means, wherein the apparatus is adapted to actuate the fluid delivery means in use so as to automatically inject fluid into body tissue during insertion of the needle into the said body tissue.
    Type: Application
    Filed: November 16, 2007
    Publication date: September 25, 2008
    Applicant: INOVIO AS
    Inventors: Iacob Mathiesen, Torunn Tjelle, Knut Arvid Sorensen Rekdahl, Bjorn David-Andersen
  • Electroporation device and injection apparatus
    Patent number: 7328064
    Abstract: An apparatus is provided for injecting a fluid into body tissue, the apparatus comprising: a hollow needle; and fluid delivery means, wherein the apparatus is adapted to actuate the fluid delivery means in use so as to automatically inject fluid into body tissue during insertion of the needle into the said body tissue.
    Type: Grant
    Filed: July 3, 2003
    Date of Patent: February 5, 2008
    Assignee: Inovio AS
    Inventors: Iacob Mathiesen, Torunn Tjelle, Knut Arvid Sørensen Rekdahl, Bjøm David-Andersen
  • Electroporation device and injection apparatus
    Publication number: 20050070841
    Abstract: An apparatus is provided for injecting a fluid into body tissue, the apparatus comprising: a hollow needle; and fluid delivery means, wherein the apparatus is adapted to actuate the fluid delivery means in use so as to automatically inject fluid into body tissue during insertion of the needle into the said body tissue.
    Type: Application
    Filed: December 31, 2003
    Publication date: March 31, 2005
    Inventors: Iacob Mathiesen, Torunn Tjelle, Knut Rekdahl, Bjorn David-Andersen
  • Electroporation device and injection apparatus
    Publication number: 20040059285
    Abstract: An apparatus is provided for injecting a fluid into body tissue, the apparatus comprising:
    Type: Application
    Filed: July 3, 2003
    Publication date: March 25, 2004
    Applicant: Inovio AS
    Inventors: Iacob Mathiesen, Torunn Tjelle, Knut Arvid Sorensen Rekdahl, Bjom David-Andersen
  • Production of multi-chain protein from muscle
    Publication number: 20040052773
    Abstract: A multi-chain protein can be produced in a subject by intramuscular injection of one or more vectors that code for the chains of the protein and, optionally, by applying one or more electrical pulses across the injection site. A preferred multi-chain protein is an immunoglobulin. This approach to antibody production has various applications, including for expressing multi-chain proteins in vivo for disease therapy and for eliciting an immune response to one or more foreign antigenic determinants of the expressed protein.
    Type: Application
    Filed: January 16, 2003
    Publication date: March 18, 2004
    Applicant: Inovio AS
    Inventors: Bjarne Bogen, Iacob Mathiesen, Torunn Tjelle