Patents by Inventor Tosaku Miki

Tosaku Miki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4985595
    Abstract: Aminobenzamide derivatives of the formula (I) ##STR1## wherein: R.sub.1 and R.sub.2 each represents a lower alkoxy group,R.sub.3 represents a hydrogen atom, a lower alkyl group, a lower acyl group, a lower alkoxycarbonyl group or --R.sub.5 --SO.sub.3 Z, wherein R.sub.5 represents a lower alkylene group and Z represents an alkali metal or an alkaline earth metal,R.sub.4 represents an amino group, a morpholino group or a lower alkylamino group which may be substituted with a hydroxyl group at the alkyl moiety thereof, with the proviso that, when R.sub.3 represents a hydrogen atom, R.sub.4 cannot be an amino group,Y represents a hydrogen atom, a halogen atom or a lower alkoxy group,n represents an integer of from 1 to 6,and salts thereof; are disclosed. These compounds have excellent anti-peptic ulcer activities, and chemical and physical stabilities.
    Type: Grant
    Filed: December 1, 1988
    Date of Patent: January 15, 1991
    Assignee: Daiichi Pharmaceutical Co., Ltd.
    Inventors: Tosaku Miki, Masahide Asano, Toru Hosokami
  • Patent number: 4297357
    Abstract: N-phenethylacetamide compounds of the formula: ##STR1## wherein X.sub.1 represents a lower alkoxy group, X.sub.2 represents a hydrogen atom or a lower alkoxy group and R represents a phenyl group, a pyridyl group, a pyrimidinyl group or a benzoyl group, each of which may have one or more substituents selected from a halogen atom, a carbamoyl group, a lower alkoxy group, a sulfamoyl group, an amino group, a lower alkylamino group, a lower alkylthio group, a hydroxy group and a lower alkoxycarbonyl group; the parmaceutically acceptable acid addition salts and hydrates thereof; as well as the process for preparing such compounds and salts and hydrates thereof; the compounds, their salts and their hydrates having a distinct anti-peptic ulcer activity in human and animals.
    Type: Grant
    Filed: August 27, 1979
    Date of Patent: October 27, 1981
    Assignee: Daiichi Seiyaku Co., Ltd.
    Inventors: Tosaku Miki, Masahide Asano
  • Patent number: 4288441
    Abstract: A compound of the formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 each represents a member selected from the group consisting of hydrogen and nicotinoyl, with the proviso that R.sub.1, R.sub.2 and R.sub.3 do not all simultaneously represent hydrogen, and the nontoxic acid addition salts thereof.
    Type: Grant
    Filed: July 30, 1980
    Date of Patent: September 8, 1981
    Assignee: Daiichi Seiyaku Co., Ltd.
    Inventors: Tosaku Miki, Akashi Eriguchi, Yasushi Abiko, Kinya Kameda
  • Patent number: 4097608
    Abstract: Compounds having the formula ##STR1## wherein R.sub.1 is phenyl or cycloalkyl and the phenyl may have at least one substituent selected from the group consisting of lower alkyl, lower alkoxy, amino and nitro; R.sub.2 is hydrogen or lower alkyl; A is --CH.sub.2 O-- or --CH.sub.2 CH(O-lower alkyl)-; n is zero (0) or one (1); when R.sub.1 together with (A).sub.n is unsubstituted phenyl, R.sub.2 is lower alkyl; and R.sub.3 is hydrogen or lower alkoxy, have anti-ulcerous action.
    Type: Grant
    Filed: December 20, 1976
    Date of Patent: June 27, 1978
    Assignee: Daiichi Seiyaku Co., Ltd.
    Inventors: Tosaku Miki, Yasuhiro Hosokawa, Tamotsu Miwa, Hiroshi Fujita, Masahide Asano, Shunzo Aibara
  • Patent number: 4057629
    Abstract: Compounds having the formula: ##STR1## wherein R.sub.1 is phenyl or cycloalkyl and the phenyl may have at least one substituent selected from the group consisting of lower alkyl, lower alkoxy, amino and nitro; R.sub.2 is hydrogen or lower alkyl; A is --CH.sub.2 O-- or --CH.sub.2 CH(O-lower alkyl)-; n is zero (0) or one (1); when R.sub.1 together with (A).sub.n is unsubstituted phenyl, R.sub.2 is lower alkyl; and R.sub.3 is hydrogen or lower alkoxy, have anti-ulcerousaction.
    Type: Grant
    Filed: December 20, 1976
    Date of Patent: November 8, 1977
    Assignee: Daiichi Seiyaku Co., Ltd.
    Inventors: Tosaku Miki, Yasuhiro Hosokawa, Tamotsu Miwa, Hiroshi Fujita, Masahide Asano, Shunzo Aibara
  • Patent number: 4025644
    Abstract: Compounds having the formula: ##STR1## wherein R.sub.1 is phenyl or cycloalkyl and the phenyl may have at least one substituent selected from the group consisting of lower alkyl, lower alkoxy, amino and nitro; R.sub.2 is hydrogen or lower alkyl; A is --CH.sub.2 O-- or --CH.sub.2 CH(O-lower alkyl)-; n is zero or 1 when R.sub.1 together with (A).sub.n is unsubstituted phenyl, R.sub.2 is lower alkyl; and R.sub.3 is hydrogen or lower alkoxy, have anti-ulcerousaction.
    Type: Grant
    Filed: December 9, 1975
    Date of Patent: May 24, 1977
    Assignee: Daiichi Seiyaku Co., Ltd.
    Inventors: Tosaku Miki, Yasuhiro Hosokawa, Tamotsu Miwa, Hiroshi Fujita, Masahide Asano, Shunzo Aibara