Patents by Inventor Toshifumi AKIZAWA

Toshifumi AKIZAWA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMYLOID-beta AGGREGATION INHIBITOR, PHARMACEUTICAL COMPOSITION FORAMYLOID-beta AGGREGATION DISEASE, AND USE APPLICATION OF SAME
    Publication number: 20230374070
    Abstract: A drug that inhibits aggregation of amyloid-?, which causes Alzheimer's disease and the like. The amyloid-? aggregation inhibitor is characterized by containing at least one of a peptide having an amino acid sequence of Sequence ID No. 1 or a peptide having an amino acid sequence of Sequence ID No. 2. A pharmaceutical composition for an amyloid-? aggregation disease is characterized by containing at least one of a peptide having an amino acid sequence of Sequence ID No. 1: GSGNR, and a peptide having an amino acid sequence of Sequence ID No. 2: GSGFK.
    Type: Application
    Filed: October 1, 2021
    Publication date: November 23, 2023
    Inventors: Toshifumi AKIZAWA, Motoaki SAITO, Youichirou HIGASHI, Rina NAKAMURA
  • Peptide exhibiting hydrolytic activity and use thereof
    Patent number: 10995119
    Abstract: The present invention provides a novel molecule that catalyzes a hydrolysis reaction and is different from enzyme proteins. The catalytic peptide according to the present invention is a catalytic peptide that catalyzes a hydrolysis reaction, including at least one peptide selected from the group consisting of the following peptides (A1) to (A4): (A1) a peptide consisting of Box A and at least one of an upstream region and a downstream region therefrom in a Tob/BTG protein; (A2) a peptide consisting of a partial region of the peptide (A1); (A3) a peptide that consists of an amino acid sequence obtained by deletion, substitution, addition, and/or insertion of one or more amino acids in an amino acid sequence of the peptide (A1) or (A2) and has hydrolysis activity; and (A4) a peptide consisting of an amino acid sequence with a sequence identity of at least 85% to the amino acid sequence of the peptide (A1) or (A2) and having hydrolysis activity.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: May 4, 2021
    Assignee: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION
    Inventors: Toshifumi Akizawa, Tadashi Yamamoto
  • NOVEL PEPTIDE EXHIBITING HYDROLYTIC ACTIVITY AND USE THEREOF
    Publication number: 20190023741
    Abstract: The present invention provides a novel molecule that catalyzes a hydrolysis reaction and is different from enzyme proteins. The catalytic peptide according to the present invention is a catalytic peptide that catalyzes a hydrolysis reaction, including at least one peptide selected from the group consisting of the following peptides (A1) to (A4): (A1) a peptide consisting of Box A and at least one of an upstream region and a downstream region therefrom in a Tob/BTG protein; (A2) a peptide consisting of a partial region of the peptide (A1); (A3) a peptide that consists of an amino acid sequence obtained by deletion, substitution, addition, and/or insertion of one or more amino acids in an amino acid sequence of the peptide (A1) or (A2) and has hydrolysis activity; and (A4) a peptide consisting of an amino acid sequence with a sequence identity of at least 85% to the amino acid sequence of the peptide (A1) or (A2) and having hydrolysis activity.
    Type: Application
    Filed: January 6, 2017
    Publication date: January 24, 2019
    Inventors: Toshifumi AKIZAWA, Tadashi YAMAMOTO