Patents by Inventor Toshifumi Hara

Toshifumi Hara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050142184
    Abstract: This invention discloses emulsion formulations comprising an aqueous carrier and the following components: triglyceride, cholesterol, phospholipid, at least one charged lipid, at least one hydrophilic biologically active molecule and, optionally, cholesteryl ester, and/or apoprotein; methods of preparing these emulsions; and the use of these emulsions as vehicles for the delivery of hydrophilic biologically active molecules to cells.
    Type: Application
    Filed: March 2, 2005
    Publication date: June 30, 2005
    Inventors: Leaf Huang, Toshifumi Hara
  • Patent number: 6890557
    Abstract: This invention discloses emulsion formulations comprising an aqueous carrier and the following components: triglyceride, cholesterol, phospholipid, at least one charged lipid, at least one hydrophilic biologically active molecule and, optionally, cholesteryl ester, and/or apoprotein; methods of preparing these emulsions; and the use of these emulsions as vehicles for the delivery of hydrophilic biologically active molecules to cells.
    Type: Grant
    Filed: May 22, 2003
    Date of Patent: May 10, 2005
    Assignee: University of Pittsburgh
    Inventors: Leaf Huang, Toshifumi Hara
  • Publication number: 20040248114
    Abstract: An object of the present invention is to provide a maxizyme that can bind to a target mRNA regardless of its conformation, and can effectively cleave the mRNA. The present invention provides a maxizyme which binds to a molecule having helicase activity.
    Type: Application
    Filed: May 17, 2004
    Publication date: December 9, 2004
    Inventors: Kazunari Taira, Tomoko Warashina, Masaki Warashina, Hiroaki Kawasaki, Toshifumi Hara, Iwao Nozawa
  • Publication number: 20030224041
    Abstract: This invention discloses emulsion formulations comprising an aqueous carrier and the following components: triglyceride, cholesterol, phospholipid, at least one charged lipid, at least one hydrophilic biologically active molecule and, optionally, cholesteryl ester, and/or apoprotein; methods of preparing these emulsions; and the use of these emulsions as vehicles for the delivery of hydrophilic biologically active molecules to cells.
    Type: Application
    Filed: May 22, 2003
    Publication date: December 4, 2003
    Inventors: Leaf Huang, Toshifumi Hara
  • Patent number: 6610321
    Abstract: This invention includes emulsion formulations comprising an aqueous carrier and the following components: triglyceride, cholesterol, phospholipid, at least one charged lipid, at least one hydrophilic biologically active molecule and, optionally, cholesteryl ester, and/or apoprotein; methods of preparing these emulsions; and the use of these emulsions for the delivery of hydrophilic biologically active molecules to cells.
    Type: Grant
    Filed: February 17, 1999
    Date of Patent: August 26, 2003
    Assignee: University of Pittsburgh
    Inventors: Leaf Huang, Toshifumi Hara
  • Publication number: 20020127272
    Abstract: The invefltion relates to a process for producing a carboxamide of formula (1.0) which comprises reacting formula (1.0)′ which an excess of urea in water, wherein the Variables in the above formulae are as described herein.
    Type: Application
    Filed: February 17, 1999
    Publication date: September 12, 2002
    Inventors: LEAF HUANG, TOSHIFUMI HARA
  • Patent number: 4129137
    Abstract: A washing apparatus for a filter press comprises a spray pipe having a number of nozzles and disposed outside of the filter plates so as to extend parallel to one side of such filter plate, a movable unit in which one end of the spray pipe opposed to a lower corner of such filter plate is pivotally mounted and which is movable in a region outside of the filter plates parallelly to the latter, a carriage supporting the movable unit and movable in a region outside of the filter plates in the direction of movement of the latter, which carriage, each time a filter plate is transferred toward a movable end plate, serves to carry the movable unit in a direction opposite to the direction of such transfer so as to position the spray pipe between separated filter plates, a mechanism for moving the movable unit to and fro when the spray pipe is positioned between separated filter plates, and a second mechanism for raising and lowering the spray pipe synchronously with the to-and-fro movement of the movable unit, these
    Type: Grant
    Filed: November 4, 1977
    Date of Patent: December 12, 1978
    Assignee: Kurita Machinery Manufacturing Company Limited
    Inventors: Tetsuya Kurita, Toshifumi Hara