Abstract: A chromatographic medium having a separating agent layer, which is used to separate target substances, and a permeation layer, which is laminated so as to face the separating agent layer and which is used to enable permeation of the target substances separated by the separating agent layer, wherein a region in which the permeation layer is not laminated is present on a part of the separating agent layer, the separating agent layer exhibits a separating property for the target substances and exhibits an optical responsiveness to ultraviolet rays, and the permeation layer exhibits an optical responsiveness that is different from those of the target substances and the separating agent layer.

Abstract: A chromatographic medium having a separating agent layer, which is used to separate target substances, a filling agent layer, which is used to fix the target substances before the target substances are separated, and a permeation layer, which is used to enable permeation of the target substances separated by the separating agent layer, wherein the filling agent layer comes into contact with the separating agent layer via a plane that intersects the direction of development of the target substances in the chromatographic medium and is positioned on the upstream side in the direction of development, the separating agent layer exhibits separability of the target substances and optical responsiveness to ultraviolet rays, and the permeation layer exhibits an optical responsiveness that is different from those of the target substances and the separating agent layer.

Abstract: A TLC plate allows the separation and detection of target substances on one plate. The TLC plate is made up of a substrate, a separating medium layer stacked on the substrate, and a permeation layer discontinuously stacked on the separating medium layer and allows the permeation of a target substance separated in the separating medium layer, wherein the separating medium layer has a separating property for the target substance and an optical responsiveness for ultraviolet rays, and the permeation layer has an optical responsiveness different from that of the separating medium layer.

Abstract: A thin-layer chromatography plate and a thin-layer chromatography uses a thin-layer chromatography plate that has a first separating agent layer, which has the same optical response as the sample, and a second separating agent layer, which is disposed adjacent thereto and has an optical response that is different from the aforementioned optical response; carries out development of the sample in the first separating agent layer; thereafter carries out further development of the spots from the first separating agent layer toward the second separating agent layer; and detects the spots in the second separating agent layer through exposure to ultraviolet radiation or a color-development treatment with a coloring agent.

Abstract: A separation/detection column that can detect a component separated by a separating agent having an optical responsivity which is the same as that of a component in a sample. The separation/detection column is configured by filling one end of a tube 1, having an ultraviolet transparency, with a first filler that has an ultraviolet responsivity and a separation ability to separate the component in the sample, and by filling the other end of the tube 1 with a second filler that has an ultraviolet responsivity which is different from that of the first filler and does not have the separation ability via a spacer 4 constituted by quartz wool, and moreover by inserting an end cap 5 constituted by quartz wool into the other end of the tube 1.

Abstract: Provided is a chromatographic medium capable of separating and detecting target substances without the use of other components. A chromatographic medium having a separating agent layer, which is used to separate target substances, a filling agent layer, which is used to fix the target substances before the target substances are separated, and a permeation layer, which is used to enable permeation of the target substances separated by the separating agent layer, wherein the filling agent layer comes into contact with the separating agent layer via a plane that intersects the direction of development of the target substances in the chromatographic medium and is positioned on the upstream side in the direction of development, the separating agent layer exhibits separability of the target substances and exhibits optical responsiveness to ultraviolet rays, and the permeation layer exhibits optical responsiveness that are different from those of the target substances and the separating agent layer.

Abstract: Provided is a chromatographic medium having a separating agent layer, which is used to separate target substances, and a permeation layer, which is laminated so as to face the separating agent layer and which is used to enable permeation of the target substances separated by the separating agent layer, wherein a region in which the permeation layer is not laminated is present on a part of the separating agent layer, the separating agent layer exhibits separating property for the target substances and exhibits optical responsiveness to ultraviolet rays, and the permeation layer exhibits optical responsiveness that are different from those of the target substances and the separating agent layer.

Abstract: An object of the present invention is to provide a TLC plate which allows separation and detection of target substances on one plate. Provided is a TLC plate comprising a substrate, a separating medium layer stacked on the substrate, and a permeation layer stacked on the separating medium layer and allowing permeation of a target substance separated in the separating medium layer, wherein the separating medium layer has separating property for the target substance and optical responsiveness for ultraviolet rays, and the permeation layer has optical responsiveness different from that of the separating medium layer.

Abstract: Disclosed is a separation/detection column that can detect a component separated by a separating agent having optical responsivity which is the same as that of a component in a sample. The separation/detection column is configured by filling one end of a tube 1, having ultraviolet transparency, with a first filler that has ultraviolet responsivity and a separation ability to separate the component in the sample, and by filling the other end of the tube 1 with a second filler that has ultraviolet responsivity which is different from that of the first filler and does not have the separation ability via a spacer 4 constituted by quartz wool, and moreover by inserting an end cap 5 constituted by quartz wool into the other end of the tube 1.

Abstract: The present invention provides a thin-layer chromatography plate and a thin-layer chromatography that can detect the separation of a component in a sample by a separating agent layer that does not permit the detection of the separation of the component in the sample by an optical response.

Abstract: Disclosed is a method for producing a target substance by separating it from a mixture using a simulated moving bed chromatography (SMBC) separation system, which can minimize decreases in separation performance due to interference from a liquid accumulation portion. A material, in which the target substance in the material can be separated using a first SMBC separation system that meets a first condition, is processed to separate and produce the target substance from the material using a second SMBC separation system that meets a second condition, wherein the particle size of a separating agent and fill length of a column tube are both greater, the pressure loss by the column is substantially the same, and the volume ratio of liquid accumulation portions in the endless flow passage of the SMBC separation system is lower.

Abstract: Disclosed is a method for producing a target substance by separating it from a mixture using a simulated moving bed chromatography (SMBC) separation system, which can minimize decreases in separation performance due to interference from a liquid accumulation portion. A material, in which the target substance in the material can be separated using a first SMBC separation system that meets a first condition, is processed to separate and produce the target substance from the material using a second SMBC separation system that meets a second condition, wherein the particle size of a separating agent and fill length of a column tube are both greater, the pressure loss by the column is substantially the same, and the volume ratio of liquid accumulation portions in the endless flow passage of the SMBC separation system is lower.

Abstract: A block valve of the present invention comprises; a block portion (1) comprised of a trunk fluid channel penetrating the block portion (1) and four branch fluid channels branching in pair from the trunk fluid channel, and four valve members (2) for permitting or cutting of communication of each of the branch fluid channels, wherein the branch fluid channels are formed so that, in an arrow direction X indicating the extending direction of the trunk fluid channel, the forward valve member (2) do not ride over the backward valve member (2). Internal volume and residence area of the block valve of the present invention are smaller than those of conventional block valve.

Abstract: An simulated moving bed chromatographic separation device (SMB device), comprising an endless flow passage (2) formed with four columns (1a) to (1d) and connecting flow passages (2a) to (2d) connecting the columns (1a) to (1d) in series, and third and fourth flow passages (5) and (6) for discharging a mobile phase from any position of the endless flowpassage (2). Regulators (5d) and (6d) and flow control valves (5e) and (6e) as flow rate adjusters for opening and closing main pipes (5a) and (6a) on the downstream side of the regulators (5d) and (6d) are provided each of in the third and fourth flow passages (5) and (6). Thus, the discharge of the mobile phase from the endless flow passage (2) can be controlled by a simple and highly durable structure.

Abstract: This invention provides a concentrator capable of drawing out a concentrate of a constant concentration. The concentrator includes a heater having a heating medium that has been heated to a temperature not less than the boiling point of a solution fed to the concentrator—whereby said heater heats the solution to evaporate the solvent to a vapor to make a mixture of the vapor and a liquid—and a gas-liquid separator for dividing the mixture into the liquid and the vapor. The concentrator provides for returning the liquid separated in the gas-liquid separator to the heater, for drawing out a portion of the liquid separated in the gas-liquid separator, for detecting the concentration of an intended component in the drawn out liquid, and for controlling the liquid draw-out so that when the concentration is above a predetermined threshold, liquid draw-out commences, and when the concentration is below the threshold, liquid draw-out stops.

Abstract: This invention provides a concentrator capable of drawing out a concentrate of a constant concentration.