Abstract: A turbine rotor consisting of a wheel made of a TiAl alloy of good heat resistance and a rotor shaft made of a steel with good bonding strength is disclosed. As the shaft material a structural steel or a martensitic heat resistant steel is used. A TiAl turbine wheel made by precision casting is butted to the shaft with insertion of a brazing filler in the butted interfaces and stress of 0.01 kgf/mm.sup.2 or higher but lower than yield stress of the shaft is applied on the butted interfaces under heating by high frequency induction heating in atmosphere of an inert gas or a reducing gas to a temperature higher than the liquidus temperature of the brazing metal but not exceeding 100.degree. C. above the liquidus temperature.

Abstract: A heat resisting alloy for use in exhaust valves low in price and excellent in the cold workability and possible to be formed into valve shapes through the cold or warm working, which consists by weight percentage of C: 0.01.about.0.1%, Si.ltoreq.2%, Mn.ltoreq.2%, Cr: 12.about.25%, Nb+Ta: 0.2.about.2.0%, Ti.ltoreq.3.5%, Al: 0.5.about.3.0%, Ni: 25.about.45%, Cu: 0.1.about.5.0%, optionally at least one element selected from W.ltoreq.3%, Mo.ltoreq.3%, and V.ltoreq.1% with (1/2W+Mo+V).ltoreq.3%, Co.ltoreq.5% with Ni+Co: 25.about.45%, Ca+Mg: 0.001.about.0.01%, one or both of B.ltoreq.0.01% and Zr: 0.001.about.0.1%, and the balance of Fe and incidental impurities.

Abstract: A heat resisting steel consists essentially of 0.005-0.20% of C, 0.01-2.0% of Si, 0.1-2.0% of Mn, 20-30% of Ni, 10-20% of Cr, 3.0-4.5% of Ti and 0.1-0.7% of Al with the ratio Ti/Al being 5-20, and the balance being substantially Fe, which is excellent in the tensile properties at the room temperature and 700.degree. C., and the creep rupture properties at the temperature of 700.degree. C.

Abstract: A titanium alloy having improved heat resistance in addition to the inherent properties of lightness and corrosion resistance. The alloy consists essentially of, by weight %, Al: 5.0-7.0%, Sn: 3.0-5.0%, Zr: 2.5-6.0%, Mo: 2.0-4.0%, Si: 0.05-0.80%, C: 0.001-0.200%, O: 0.05-0.20%, optionally further one or two of Nb and Ta: 0.3-2.0%, and the balance of Ti and inevitable impurities. A method of producing parts from this alloy comprises subjecting the titanium alloy of the above described alloy composition to heat treatment at a temperature of .beta.-region, combination of rapid cooling and slow cooling or combination of water quenching and annealing, hot processing in .alpha.+.beta. region, solution treatment and aging treatment.

Abstract: A heat resisting alloy of Fe--Cr--Ni type for exhaust valves, knit meshes for the catalyzer and the like which is low in price and excellent in high temperature properties, which consists essentially by weight percentage of C:0.01.about.0.10%, S:.ltoreq.2.0%, Mn .ltoreq.2.0%, Cr:14.about.18%, Nb+Ta:0.5.about.1.5%, Ti:2.0.about.3.0%, Al:0.8.about.1.5%, Ni:30.about.35%,B:0.001.about.0.01%, Ca+Mg:0.001.about.0.01%,Cu.ltoreq.0.5%, P.ltoreq.0.02%, S.ltoreq.0.01%, O.ltoreq.0.01%, N.ltoreq.0.01%, and the balance of Fe, additionally the total atomic percentage of Al, Ti, Nb and Ta:5.0.about.7.0%, and atomic percentage ratio of Ti/Al:1.0.about.1.5, and M-value calculated from the following equation .ltoreq.0.95;M=?0.717 Ni(at. %)+0.858 Fe(at. %)+1.142 Cr(at. %)+1.90 Al(at. %)+2.271 Ti(at. %)+2.117 Nb(at. %)+2.224 Ta(at. %)+1.001 Mn(at. %)+1.90 Si(at. %)!/100.

Abstract: A heat resisting alloy for use in exhaust valves and the like low in price and excellent in structural stability, high-temperature strength and hot workability, which consists essentially by weight percentage of C: 0.01.about.0.10%, Si.ltoreq.2.0%, Mn.ltoreq.2.0%, Cr: 14.about.20%, Nb+Ta: 0.3.about.1.5%, Ti: 1.5.about.3.5%, Al: 0.5.about.1.5%, Ni+Co: 35.about.45%, B: 0.001.about.0.01%, one or both of Ca: 0.001.about.0.03% and Mg: 0,001.about.0.03%, and the balance of Fe, additionally the total atomic percentage of Al, Ti, Nb, and Ta: 4.5.about.6.0%, an atomic percentage ratio of Ti/Al: 1.0.about.2.0, and M-value obtained through the following equation.ltoreq.0.925;M=0.717 Ni (atomic fraction)+0.858 Fe (atomic fraction)+1.142 Cr (atomic fraction)+1.90 Al (atomic fraction)+2.271 Ti (atomic fraction)+2.117 Nb (atomic fraction)+1.001 Mn (atomic fraction)+1.90 Si (atomic fraction)+0.777 Co (atomic fraction)+2.224 Ta (atomic fraction).

Abstract: A Ti-Al type lightweight heat-resistant consists essentially of 32 to 36% w of Al, 0.1 to 2.0% w of Si, 0.1 to 5.0% w of Nb, 0.1 to 3.0% w of Cr, and optionally 0.005 to 0.200% w of B, the balance being substantially Ti. The alloy has improved oxidation resistance together with excellent ductility and strength at room temperature and high temperature.

Abstract: Disclosed is a method of jointing a member of Ti-Al alloy which mainly consists of an intermetallic compound, TiAl, and a member of structural steel. The jointing uses an intermediate member made of an austenitic stainless steel or a heat resistant steel, or a Ni-based or Co-based superalloy, between the above two members, and the jointing of the intermediate member and the structural steel member at least is carried out by friction welding. A typical example of the jointed machine part manufactured by this method is an engine valve.

Abstract: A compound of the formula ##STR1## wherein Y is sulfur or methylene and A is Asn or Asp, or a pharmaceutically acceptable salt thereof is useful for the treatment of calcium metabolic disorders, cardiac disease and ulcers, and for the improvement of cranial circulation.

Abstract: A compound of the formula ##STR1## wherein R is H or H-Ala-NH- and when A is Asp, B is Asp or Glu, C is Leu and D is Val; when A is Asn and B is Gly, C is Phe and D is Gly; when A is Asn, B is Asp or Glu and C is Leu, D is Gly; and when A is Asn, B is Asp or Glu, and C is Phe, D is Val, or a pharmaceutically acceptable salt thereof, is useful for the treatment of calcium metabolic disorders, cardiac disease and ulcers, and for the improvement of cerebral circulation.

Abstract: Disclosed are Ti-Al alloys having increased ductility and Ti-Al alloys having increased ductility and lowered melting points, in both of which the main constituent phase is an intermetallic compound, TiAl.The Ti-Al alloys having increased ductility essentially consisting of Al: 28-38%, and B: 0.005-0.3%, the balance being Ti and inevitable impurities.Since the alloys of this type have good processability, they are suitable as materials for mechanical parts of rotating or reciprocating systems, where high heat-resistance and high specific strength are required.The Ti-Al alloys having increased ductility as well as lowered melting points essentially consisting of Al: 28-38%, one or two of Ni: 0.05-3.0% and Si: 0.05-3.0%, and the balance being Ti and inevitable impurities. Optionally, this alloy further contains B: 0.005-0.3%.The alloy of this type is, in addition to the above use, suitable for producing machine parts made by precision casting technology.

Abstract: A peptide represented by the following formula: ##STR1## wherein Y means a sulfur atom or methylene group, A stands for Asp or Asn, B denotes Val or Met and C is Asn or Ser, or a salt thereof.

Abstract: A peptide of the formula ##STR1## wherein A is Tyr or Phe, or a pharmaceutically acceptable salt thereof, is useful for the diagnosis of parathyroid gland function. When A is Tyr, the peptide can be labelled with iodine-125 without losing its PTH activity and without undergoing oxidation upon storage.

Abstract: A novel peptide of the formulaH--Ser--Arg--Arg--Ala--Gln--Asp--Phe--Val--Gln--Trp--Leu--Met--Asn--Thr--OHis the 16-29 fragment of glucagon and can be conjugated with a protein such as albumin or modified albumin using glutaraldehyde or 3-(2'-benzothiazolyl-dithio) propionate succinimide ester as a conjugation reagent. The conjugated peptide can be used to sensitize a mammal by administering the conjugated peptide subcutaneously, after which the blood is collected from the mammal and antibodies concentrated from the blood, which antibodies are then useful in assay methods for trace amounts of glucagon in human blood.

Abstract: A peptide of the formulaR--Lys--Lys--Glu--Asp--Asn--Val--Leu--Val--Glu--Ser--His--Glu--Lys--Ser--Le u--Gly--Glu--Ala--Asp--Lys--Ala--Asp--Val--Asp--Val--Leu--Thr--Lys--Ala--Ly s--Ser--Gln--Ohwherein R is H, H--Tyr-- or R.sub.1 --Pro--Arg--, R.sub.1 is H, H--Tyr-- or R.sub.2 --Ala--Gly--Ser--Gln--Arg--, and R.sub.

Abstract: A peptide of the formulaR-SER-LEU-PRO-SER-PRO-SER-ARG-LEU-PRO-GLY-PRO-SER-ASP-THR-PRO-ILE-LEU-PRO-G LN-OHwhereinR: H or R.sub.1 -Ser-Ser-Ser-Ser-Lys-Ala-Pro-Pro-Pro group,R.sub.1 : H or R.sub.2 -R.sub.3 -Asp-Asp-Pro-Arg-Phe-Gln-Asp group,R.sub.2 : H or R.sub.4 -Asp-His-Pro-Leu-Thr group,R.sub.4 : H-R.sub.5 -Gly-Gly-Pro-Lys group,R.sub.5 : Cys or Tyr group, andR.sub.3 : Cys or S-acetamidemethyl-Cys group,or salt thereof, has utility for the preparation of antibodies for assaying human chorionic gonadotropin or as a labelling reagent.

Abstract: Novel amine compounds of the formula ##STR1## wherein R.sub.1 is lower alkyl and R.sub.2 is substituted methyl amino or D-amino acid residue, or a salt thereof. R.sub.1 can typically be isobutyl or methyl; and R.sub.2 can be methylamino of the formula--NH--CH.sub.2 --R.sub.3in which R.sub.3 is organic, more particularly methyl, ethyl, n-propyl, isopropyl, n-butyl, amyl, p-hydroxybenzyl, 3,4-di-hydroxybenzyl, 5-imidazolemethyl, 3-imidazolemethyl or phenyl. R.sub.2 can also be D-amino acid residue of the formula ##STR2## in which one of R.sub.4 and R.sub.5 is carboxyl and the other is organic, more particularly methylthioethyl, isobutyl, methyl or phenyl, and C* is a D-asymmetric carbon atom. The compounds are useful in an assay method for leucine and aminopeptidase which comprises reacting a substrate amide as above, or a salt thereof, with a sample for leucine aminopeptidase assay, incubating the reaction product produced thereby, and measuring the thus-consumed oxygen or liberated hydrogen peroxide.

Abstract: Polypeptides of the formula ##STR1## wherein A.sub.1 is Ser or Gly, A.sub.7 is Val or Met, A.sub.10 is Lys or Thr, A.sub.11 is Leu or Tyr, A.sub.12 is Ser or Thr, A.sub.14 is Glu or Asp, A.sub.15 is Leu or Phe, A.sub.16 is His or Asn, A.sub.18 is Leu or Phe, A.sub.19 is Gln or His, A.sub.21 is Tyr or Phe, A.sub.23 is Arg or Gln, A.sub.25 is Asp or Asn or Ala, A.sub.26 is Val or Thr or Ile, A.sub.28 is Ala or Ser or Val, and A.sub.30 is Thr or Val or Ala, and pharmaceutically acceptable acid addition salts and complexes, have serum calcium reducing activity.

Abstract: A polypeptide having calcitonin activity of the formula ##EQU1## and the salts thereof with pharmaceutically acceptable acids.

Abstract: A peptide of the formulaR--Lys--Lys--Glu--Asp--Asn--Val--Leu--Val--Glu--Ser--His--Glu--Lys--Ser--Le u--Gly--Glu--Ala--Asp--Lys--Ala--Asp--Val--Asp--Val--Leu--Thr--Lys--Ala--Ly s--Ser--Gln--OHwherein R is H, H--Tyr-- or R.sub.1 --Pro--Arg--, R.sub.1 is H, H--Tyr-- or R.sub.2 --Ala--Gly--Ser--Gln--Arg--, and R.sub.2 is H, H--Cys-- or H--Tyr--, or a salt thereof, is useful for assaying human parathyroid hormone (h-PTH).