Patents by Inventor Toshihide Kokura

Toshihide Kokura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 3-aminoquinuclidines
    Patent number: 5852038
    Type: Grant
    Filed: November 18, 1996
    Date of Patent: December 22, 1998
    Assignee: Pfizer Inc
    Inventors: Fumitaka Ito, Toshihide Kokura, Masami Nakane, Kunio Satake, Hiroaki Wakabayashi
  • Substituted quinuclidines as substance P antagonists
    Patent number: 5837711
    Abstract: Certain novel substituted quinuclidine compounds having the ability to antagonize substance P and having the following formula: ##STR1## wherein Ar.sup.1 and Ar.sup.2 are each, independently, thienyl, phenyl, fluorophenyl, chlorophenyl or bromophenyl;X is --CONR.sup.3 R.sup.4, --CO.sub.2 R.sup.3, --CH.sub.2 OR.sup.3, --CH.sub.2 NR.sup.3 R.sup.4 or --CONR.sup.3 OR.sup.4 ;R.sup.1, R.sup.3 and R.sup.4 are each, independently, hydrogen or alkyl having 1 to 4 carbon atoms;R.sup.
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: November 17, 1998
    Assignee: Pfizer Inc.
    Inventors: Fumitaka Ito, Toshihide Kokura, Masami Nakane, Kunio Satake, Hiroaki Wakabayashi
  • Substituted 3-aminoquinuclidines
    Patent number: 5716965
    Abstract: Compounds of the formula ##STR1## wherein W, Ar.sup.1, Ar.sup.2 and Ar.sup.3 are defined as below; and the pharmaceutically acceptable salts of such compounds.These compounds are substance P antagonists and useful in the treatment of gastrointestinal disorders, inflammatory disorders, central nervous system disorders and pain.
    Type: Grant
    Filed: December 20, 1993
    Date of Patent: February 10, 1998
    Assignee: Pfizer Inc.
    Inventors: Fumitaka Ito, Toshihide Kokura, Masami Nakane, Kunio Satake, Hiroaki Wakabayashi
  • 1,3-dicarbonyl compounds and their use
    Patent number: 5166161
    Abstract: 3-Oxo-4-acyl or carbamyl-bicyclic aromatic and heterocyclic compounds as inhibitors of cyclooxygenase and lipoxygenase and useful as antiallergy and antiinflammatory agents.
    Type: Grant
    Filed: January 22, 1991
    Date of Patent: November 24, 1992
    Assignee: Pfizer Inc.
    Inventors: Toshihide Kokura, Kazunari Nakao, Fumitaka Ito, Masami Nakane