Patents by Inventor Toshihiko Kaneko
Toshihiko Kaneko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5475024Abstract: A new benzodioxole derivative has a substituent in the phenyl ring which is a carboxyalkylthioalkyl or the like and is effective to treat a liver disease.Type: GrantFiled: October 14, 1993Date of Patent: December 12, 1995Assignee: Eisai Co., Ltd.Inventors: Yoshitake Ogata, Makoto Ikeda, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Takashi Yamanaka, Ieharu Hishinuma, Junichi Nagakawa, Kazuo Hirota, Kaname Miyamoto, Toru Horie, Tsuneo Wakabayashi
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Patent number: 5298649Abstract: A naphthalene derivative having the formula is new and useful for medicine. ##STR1## wherein R.sup.1 represents a hydrogen atom, a lower alkyl group or an acyl group;R.sup.2 independently represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogen atom, a cycloalkyl group, a cycloalkylalkyl group, a hydroxyl group, an aryl group which may be substituted, an arylalkyl group whose aryl group may be substituted, a heteroaryl group, or a heteroarylalkyl group;R.sup.3 and R.sup.4 are the same or different and represent a hydrogen atom, a lower alkyl group, a lower alkenyl group, an aryl group which may have a substituent, an arylalkyl group whose aryl group may be substituted, an arylalkenyl group whose aryl group may be substituted, a cycloalkyl group, an alkoxyalkyl group, a heteroaryl group, a heteroarylalkyl group, a carboxyl group, a carboxyalkyl group, an aminoalkyl group, or a cyano group;R.sup.5 represents a group of the formula, --OR.sup.7, (wherein R.sup.Type: GrantFiled: October 10, 1991Date of Patent: March 29, 1994Assignee: Eisai Co., Ltd.Inventors: Makoto Okita, Hiroshi Shirota, Masayuki Tanaka, Toshihiko Kaneko, Katsuya Tagami, Shigeki Hibi, Yasushi Okamoto, Seiichiro Nomoto, Takeshi Suzuki, Kenichi Chiba, Masaki Goto, Ryoichi Hashida, Hideki Ono, Hideto Ohhara, Hideki Sakurai, Shigeru Souda, Yoshimasa Machida, Kouichi Katayama, Isao Yamatsu
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Patent number: 5292901Abstract: A new benzodioxole derivative has a substituent in the phenyl ring which is a carboxyalkylthioalkyl or the like and is effective to treat a liver disease.Type: GrantFiled: February 6, 1992Date of Patent: March 8, 1994Assignee: Eisai Co., Ltd.Inventors: Yoshitake Ogata, Makoto Ikeda, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Takashi Yamanaka, Ieharu Hishinuma, Junichi Nagakawa, Kazuo Hirota, Kaname Miyamoto, Toru Horie, Tsuneo Wakabayashi
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Patent number: 5251690Abstract: An apparatus for collecting cleaning bodies in a tubular heat exchanger capable of collecting the cleaning bodies with a high collection efficiency against the temporary introduction of a large amount foreign matter such as falling tools in a cooling water system and against the deflected flow of the cooling water from the upstream side. A rectifying member rectifies or regulates the deflected flow of the cooling water from the upstream side whereby it is possible to collect the cleaning bodies without any adhesion and stagnation of the cleaning bodies in the cooling water on V-shaped collection lattices. It is also possible to trap a large article such as a falling tool between a guide member disposed downstream of the collection lattices and the collection lattices, and to introduce only the cleaning bodies into the guide member. Furthermore, the downstream port of a cleaning body discharge pipe opens toward the downstream side to thereby prevent the clogging of the port with the foreign matter or the like.Type: GrantFiled: May 14, 1991Date of Patent: October 12, 1993Assignees: Hitachi, Ltd., Hitachi Machinery and Engineering, Ltd.Inventors: Katsumoto Otake, Yoshio Sumiya, Yasuo Fujitani, Shigeo Oda, Tokunori Matsushima, Takuya Sasaki, Keizo Ishida, Hideki Kon, Hiroshi Satoh, Toshihiko Kaneko, Makoto Yanagihara
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Patent number: 5239079Abstract: A pyridinium salt is useful as an antiulcer and is defined by the following formula. It includes a sulphenamide compound and a pyridinium compound. J is benzoimidazole, K is --S-- or --SSR, Z is hydroxy or oxyalkyl.Type: GrantFiled: August 13, 1992Date of Patent: August 24, 1993Assignee: Eisai Co., Ltd.Inventors: Shigeru Souda, Shuhei Miyazawa, Norihiro Ueda, Katsuya Tagami, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Masatoshi Fujimoto, Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki, Hisashi Shibata, Tsuneo Wakabayashi
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Patent number: 5207267Abstract: A stroke-end position of an injection cylinder of the die cast machine is detected and a position of the injection cylinder for sending a boosting-signal is set. This position is a predetermined standard boost stroke distance from the stroke-end position. When the injection cylinder reaches the position for sending the boosting-signal in the casting cycle, an oil-pressure intensifier is advanced. In this method, before casting is performed, a value representing a stroke after slowing-down and a setting value of the plunger stopping position are determined and the start point for slowing-down is calculated by subtracting the value of the stroke after slowing down from the setting value.Type: GrantFiled: August 9, 1991Date of Patent: May 4, 1993Assignee: Toshiba Kikai Kabushiki KaishaInventors: Norihiro Iwamoto, Masayuki Takamura, Toshihiko Kaneko
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Patent number: 5162317Abstract: A pyridinium salt useful as an antiulcer agent, defined by formula (I) is disclosed. It includes a sulphenamide compound and a pyridinium compound. J is benzimidazole, K is --S-- or --SSR-- and Z is hydroxy or alkoxy.Type: GrantFiled: December 5, 1989Date of Patent: November 10, 1992Assignee: Esai Co., Ltd.Inventors: Shigeru Souda, Shuhei Miyazawa, Norihiro Ueda, Katsuya Tagami, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Masatoshi Fujimoto, Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki, Hisashi Shibata, Tsuneo Wakabayashi
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Patent number: 5134111Abstract: A naphthalene derivative having the formula is new and useful for medicine. ##STR1## [wherein R.sup.1 represents a hydrogen atom, a lower alkyl group or an acyl group;R.sup.2 independently represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogen atom, a cycloalkyl group, a cycloalkylalkyl group, a hydroxyl group, an aryl group which may be substituted, an arylalkyl group whose aryl group may be substituted, a heteroaryl group, or a heteroarylalkyl group;R.sup.3 and R.sup.4 are the same or different and represent a hydrogen atom, a lower alkyl group, a lower alkenyl group, an aryl group which may have a substituent, an arylalkyl group whose aryl group may be substituted, an arylalkenyl group whose aryl group may be substituted, a cycloalkyl group, an alkoxyalkyl group, a heteroaryl group, a heteroarylalkyl group, a carboxy group, a carboxyalkyl group, an aminoalkyl group, or a cyano group;R.sup.5 represents a group of the formula, --OR.sup.7, (wherein R.sup.Type: GrantFiled: December 15, 1989Date of Patent: July 28, 1992Assignee: Eisai Co., Ltd.Inventors: Makoto Okita, Hiroshi Shirota, Masayuki Tanaka, Toshihiko Kaneko, Katsuya Tagami, Shigeki Hibi, Yasushi Okamoto, Seiichiro Nomoto, Takeshi Suzuki, Kenichi Chiba, Masaki Goto, Ryoichi Hashida, Hideki Ono, Hideto Ohhara, Hideki Sakurai, Shigeru Souda, Yoshimasa Machida, Kouichi Katayama, Isao Yamatsu
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Patent number: 5110956Abstract: A new benzodioxole derivative has a substituent in the phenyl ring which is a carboxyalkylthioalkyl or the like and is effective to treat a liver disease.Type: GrantFiled: April 23, 1990Date of Patent: May 5, 1992Assignee: Eisai Co., Ltd.Inventors: Yoshitake Ogata, Makoto Ikeda, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Takashi Yamanaka, Ieharu Hishinuma, Junichi Nagakawa, Kazuo Hirota, Kaname Miyamoto, Toru Horie, Tsuneo Wakabayashi
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Patent number: 5089035Abstract: A dehumidifier for removing moisture contained in air upon discharging the air which has been introducing from outside, comprises a container body, a meshed receptacle which is suspended through a receiving mouth formed on top of the container body and accommodates therein a deliquescent moisture absorbent, and a cover which covers the top end of the container body excluding the receiving mouth. On the top end of the container body, there are provided a receiving tube which is suspended therein and the bottom portion of a battery chamber. In the cover, there are provided an air sending tube which forms a vent passage together with the receiving tube being located within the receiving tube and is suspended lower than the receiving tube and a cover which forms the battery chamber together with the bottom portion of the battery chamber of the container body. Further, on the top of the air sending tube, a fan and its driving source are provided.Type: GrantFiled: December 27, 1989Date of Patent: February 18, 1992Assignee: Esute Chemical CorporationInventor: Toshihiko Kaneko
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Patent number: 5045552Abstract: Pyridine derivatives useful for preventing or treating peptic ulcers, pharmaceutical preparations and methods of treating peptic ulcers are described.Type: GrantFiled: December 28, 1989Date of Patent: September 3, 1991Assignee: Eisai Co., Ltd.Inventors: Shigeru Souda, Norihiro Ueda, Shuhei Miyazawa, Katsuya Tagami, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Masatoshi Fujimoto, Manabu Murakami, Kiyoshi Oketani, Hideaki Fujisaki, Hisashi Shibata, Tsuneo Wakabayashi
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Patent number: 5022457Abstract: This invention relates to a casting control system of a die cast machine, and more particularly to a system for controlling a high speed injection real stroke of an injection plunger and controlling valve closing timing for degassing gas in a mold cavity. The high speed injection real stroke is measured by an arithmetic unit from a signal output from a position detector, and the high speed injection real stroke is then compared with a certain preset value. When arithmetic unit determines that the high speed injection real stroke and the preset value do not coincide with each other, a pretest action delay time of the injection plunger is .+-. incrementally or decrementally corrected until both values coincide.Type: GrantFiled: January 30, 1989Date of Patent: June 11, 1991Assignee: Toshiba Machine Co., Ltd.Inventors: Norihiro Iwamoto, Hiroyuki Tsuboi, Toshihiko Kaneko
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Patent number: 4932458Abstract: A method of and a system for operating a squeeze plunger in a die cast machine. When the fill-up of molten metal in a cavity is completed by an injection plunger, the moving speed of the injection plunger is rapidly decreased. When the speed at this time becomes lower than a preset value, a preset delay time is measured. After a lapse of this delay time, the squeeze plunger is operated to press a molding material in the cavity, so that plastic flows are caused in the molding material.Type: GrantFiled: January 25, 1989Date of Patent: June 12, 1990Assignee: Toshiba Machine Co., Ltd.Inventors: Norihiro Iwamoto, Hiroyuki Tsuboi, Toshihiko Kaneko
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Patent number: 4907190Abstract: In a computer system suitable for effecting a sequence control and a servo-control, programs are prepared by using three types of parallel processing instructions consisting of an open instruction, a close instruction is issued from a first program for parallelly processing a second program. The close instruction is issued from the first program to terminate the first or second program. The pause instruction is issued from the first program to stop execution of the first program for a definite interval.Type: GrantFiled: August 8, 1986Date of Patent: March 6, 1990Assignee: Toshiba Kikai Kabushiki KaishaInventors: Yoshinari Sasaki, Etsuji Oda, Naoki Kurita, Toshihiko Kaneko
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Patent number: 4768676Abstract: A container for volatile liquid aromatics to perfume the air is disclosed, in which a cylindrical tube having a closed lower end and accomodating the absorbing core portion of a volatilizing structure extends downward from the top of the container into liquid aromatics stored in the main container body. Thus, the volatilizing structure is kept dry prior to use. The container also comprises an opener for the lower end of the tube receiving the absorbing core portion of the volatilizing structure. The opener may consist of a needle-shaped pin extending in the tube. Simple activation of the opener by the user of the container is sufficient to commence vaporization. The volatilizing portion of the volatilizing structure is preferably in the form of an elongated strip whose widthwise direction is vertically disposed and which is curved lengthwise into a fold.Type: GrantFiled: December 7, 1987Date of Patent: September 6, 1988Assignee: S.T. Chemical Co., Ltd.Inventor: Toshihiko Kaneko